Patents by Inventor Michael J. Collins, Sr.
Michael J. Collins, Sr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210116336Abstract: An extraction method for preparing samples for analytical analysis is disclosed. The method includes the steps of placing a sample matrix containing one or more analytes in a heat conductive sample cup, positioning the heat conductive sample cup in a pressure-resistant reaction chamber, dispensing solvent into the heat conductive sample cup, dispersing the solvent and the sample matrix in the sample cup in the reaction chamber, heating the sample matrix and the extraction solvent in the heat conductive sample cup in the reaction chamber to a temperature at which the dispensed solvent generates an above-atmospheric pressure, and releasing the extraction solvent extract from the sample cup at atmospheric pressure.Type: ApplicationFiled: January 16, 2020Publication date: April 22, 2021Applicant: CEM CorporationInventors: Michael J. Collins, SR., Joseph J. Lambert, Matthew N. Beard, Paul C. Elliott
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Patent number: 10677696Abstract: An extraction method for preparing samples for analytical analysis is disclosed. The method includes the steps of placing a sample matrix containing one or more analytes in a heat conductive sample cup, positioning the heat conductive sample cup in a pressure-resistant reaction chamber, dispensing solvent into the heat conductive sample cup, dispersing the solvent and the sample matrix in the sample cup in the reaction chamber, heating the sample matrix and the extraction solvent in the heat conductive sample cup in the reaction chamber to a temperature at which the dispensed solvent generates an above-atmospheric pressure, and releasing the extraction solvent extract from the sample cup at atmospheric pressure.Type: GrantFiled: August 22, 2018Date of Patent: June 9, 2020Assignee: CEM CorporationInventors: Michael J. Collins, Sr., Joseph J. Lambert, Matthew N. Beard, Paul C. Elliott
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Publication number: 20190291070Abstract: A combination for carrying out microwave assisted reactions is disclosed, such as acid digestion and solvent extraction. The combination includes a microwave transparent pressure-resistant reaction vessel and a flexible film fluoropolymer liner inside the reaction vessel. The flexible film liner has a size and shape that substantially conforms to the inner walls of the reaction vessel. A pressure-relief closure is positioned on the reaction vessel and the flexible film liner, and an infrared temperature detector that operates in wavelengths (frequencies) to which both the reaction vessel and the flexible liner are transparent, so that an exact fit and conductive heating to the outside of the reaction vessel are not required.Type: ApplicationFiled: March 23, 2018Publication date: September 26, 2019Applicant: CEM CorporationInventors: Wyatt P. Hargett, JR., Michael J. Collins, SR.
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Publication number: 20190257726Abstract: An energized dispersive extraction method for sample preparation for analysis is disclosed. The method includes the steps of placing an extraction solvent, sorbent particles, and a sample matrix containing an analyte in a heat conductive sample cup; positioning the sample cup in a pressure-resistant reaction chamber; dispersing the solvent and the sample matrix in the sample cup in the reaction chamber; heating the sample matrix and the solvent in the sample cup in the reaction chamber to a temperature that generates an above-atmospheric pressure; draining the solvent extract from the sample cup at atmospheric pressure; and collecting the solvent extract for analysis.Type: ApplicationFiled: March 20, 2019Publication date: August 22, 2019Applicant: CEM CorporationInventors: Michael J. Collins, SR., Joseph J. Lambert, Matthew N. Beard, Paul C. Elliott
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Patent number: 10330573Abstract: An extraction method for preparing samples for analytical analysis is disclosed. The method includes the steps of placing a sample matrix containing one or more analytes in a heat conductive sample cup, positioning the heat conductive sample cup in a pressure-resistant reaction chamber, dispensing solvent into the heat conductive sample cup, dispersing the solvent and the sample matrix in the sample cup in the reaction chamber, heating the sample matrix and the extraction solvent in the heat conductive sample cup in the reaction chamber to a temperature at which the dispensed solvent generates an above-atmospheric pressure, and releasing the extraction solvent extract from the sample cup at atmospheric pressure.Type: GrantFiled: July 10, 2017Date of Patent: June 25, 2019Assignee: CEM CorporationInventors: Michael J. Collins, Sr., Joseph J. Lambert, Matthew N. Beard, Paul C. Elliott
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Patent number: 10295447Abstract: An energized dispersive extraction method for sample preparation for analysis is disclosed. The method includes the steps of placing an extraction solvent, sorbent particles, and a sample matrix containing an analyte in a heat conductive sample cup; positioning the sample cup in a pressure-resistant reaction chamber; dispersing the solvent and the sample matrix in the sample cup in the reaction chamber; heating the sample matrix and the solvent in the sample cup in the reaction chamber to a temperature that generates an above-atmospheric pressure; draining the solvent extract from the sample cup at atmospheric pressure; and collecting the solvent extract for analysis.Type: GrantFiled: July 10, 2017Date of Patent: May 21, 2019Assignee: CEM CorporationInventors: Michael J. Collins, Sr., Joseph J. Lambert, Matthew N. Beard, Paul C. Elliott
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Patent number: 10241014Abstract: An instrument for extraction based molecular sample preparation and related processes is disclosed. The instrument includes a thermally conductive pressure resistant heating chamber and a thermally conductive sample cup positioned in the thermally conductive pressure resistant healing chamber for heating liquids and solids together in the thermally conductive sample cup. A liquid delivery inlet fixture in the thermally conductive pressure resistant heating chamber delivers liquids (solvent) from a supply to the thermally conductive sample cup in the thermally conductive pressure resistant heating chamber, and a chiller in liquid communication with the thermally conductive sample cup in the thermally conductive pressure resistant heating chamber receives heated liquids from the thermally conductive pressure resistant heating chamber when the chamber is opened to atmospheric pressure.Type: GrantFiled: July 10, 2017Date of Patent: March 26, 2019Assignee: CEM CorporationInventors: Michael J. Collins, Sr., Joseph J. Lambert, Matthew N. Beard, Paul C. Elliott
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Publication number: 20190011337Abstract: An extraction method for preparing samples for analytical analysis is disclosed. The method includes the steps of placing a sample matrix containing one or more analytes in a heat conductive sample cup, positioning the heat conductive sample cup in a pressure-resistant reaction chamber, dispensing solvent into the heat conductive sample cup, dispersing the solvent and the sample matrix in the sample cup in the reaction chamber, heating the sample matrix and the extraction solvent in the heat conductive sample cup in the reaction chamber to a temperature at which the dispensed solvent generates an above-atmospheric pressure, and releasing the extraction solvent extract from the sample cup at atmospheric pressure.Type: ApplicationFiled: July 10, 2017Publication date: January 10, 2019Applicant: CEM CorporationInventors: Michael J. Collins, Sr., Joseph J. Lambert, Matthew N. Beard, Paul C. Elliott
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Publication number: 20190011339Abstract: An energized dispersive extraction method for sample preparation for analysis is disclosed. The method includes the steps of placing an extraction solvent, sorbent particles, and a sample matrix containing an analyte in a heat conductive sample cup; positioning the sample cup in a pressure-resistant reaction chamber; dispersing the solvent and the sample matrix in the sample cup in the reaction chamber; heating the sample matrix and the solvent in the sample cup in the reaction chamber to a temperature that generates an above-atmospheric pressure; draining the solvent extract from the sample cup at atmospheric pressure; and collecting the solvent extract for analysis.Type: ApplicationFiled: July 10, 2017Publication date: January 10, 2019Applicant: CEM CorporationInventors: Michael J. Collins, SR., Joseph J. Lambert, Matthew N. Beard, Paul C. Elliott
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Publication number: 20190011338Abstract: An instrument for extraction based molecular sample preparation and related processes is disclosed. The instrument includes a thermally conductive pressure resistant heating chamber and a thermally conductive sample cup positioned in the thermally conductive pressure resistant heating chamber for heating liquids and solids together in the thermally conductive sample cup. A liquid delivery inlet fixture in the thermally conductive pressure resistant heating chamber delivers liquids (solvent) from a supply to the thermally conductive sample cup in the thermally conductive pressure resistant heating chamber, and a chiller in liquid communication with the thermally conductive sample cup in the thermally conductive pressure resistant heating chamber receives heated liquids from the thermally conductive pressure resistant heating chamber when the chamber is opened to atmospheric pressure.Type: ApplicationFiled: July 10, 2017Publication date: January 10, 2019Applicant: CEM CorporationInventors: Michael J. Collins, SR., Joseph J. Lambert, Matthew N. Beard, Paul C. Elliott
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Publication number: 20190011341Abstract: An extraction method for preparing samples for analytical analysis is disclosed. The method includes the steps of placing a sample matrix containing one or more analytes in a heat conductive sample cup, positioning the heat conductive sample cup in a pressure-resistant reaction chamber, dispensing solvent into the heat conductive sample cup, dispersing the solvent and the sample matrix in the sample cup in the reaction chamber, heating the sample matrix and the extraction solvent in the heat conductive sample cup in the reaction chamber to a temperature at which the dispensed solvent generates an above-atmospheric pressure, and releasing the extraction solvent extract from the sample cup at atmospheric pressure.Type: ApplicationFiled: August 22, 2018Publication date: January 10, 2019Applicant: CEM CorporationInventors: Michael J. Collins, SR., Joseph J. Lambert, Matthew N. Beard, Paul C. Elliott
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Publication number: 20190011340Abstract: An instrument for extraction based molecular sample preparation and related processes is disclosed. The instrument includes a thermally conductive pressure resistant heating chamber and a thermally conductive sample cup positioned in the thermally conductive pressure resistant heating chamber for heating liquids and solids together in the thermally conductive sample cup. A liquid delivery inlet fixture in the thermally conductive pressure resistant heating chamber delivers liquids (solvent) from a supply to the thermally conductive sample cup in the thermally conductive pressure resistant heating chamber, and a chiller in liquid communication with the thermally conductive sample cup in the thermally conductive pressure resistant heating chamber receives heated liquids from the thermally conductive pressure resistant heating chamber when the chamber is opened to atmospheric pressure.Type: ApplicationFiled: May 25, 2018Publication date: January 10, 2019Applicant: CEM CorporationInventors: Michael J. Collins, SR., Joseph J. Lambert, Matthew N. Beard, Paul C. Elliott
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Patent number: 9921282Abstract: A method of measuring NMR response in an NMR instrument includes heating a sample at a heater temperature that is higher than the temperature of the interior of the NMR instrument, positioning the heated sample in the NMR instrument, and measuring the NMR response of the heat sample. Typically, the sample is dry and includes fat. Furthermore, a method of determining an amount of a component of a sample includes positioning a sample in an NMR instrument, applying a sequence of radio-frequency pulses to the sample, measuring the amplitudes of the signals produced by the application of the sequence of radio-frequency pulses, and determining the amount of a component in the sample using the measured amplitudes of the signals. The disclosed methods typically provide accurate analysis of samples in a shorter time period than traditional NMR techniques and solvent-based analysis techniques.Type: GrantFiled: April 9, 2013Date of Patent: March 20, 2018Assignee: CEM CorporationInventors: Michael J. Collins, Sr., Jonathan M. Collins, Colin L. Simpson
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Publication number: 20150301061Abstract: A dye binding method for protein analysis is disclosed. The method includes the steps of preparing an initial reference dye solution of unknown concentration from an initial reference dye concentrate and creating an electronic signal based upon the absorbance of the initial reference dye solution. Thereafter, an electronic signal is created based upon the absorbance of a dye filtrate solution prepared from the initial reference dye solution and an initial protein sample. The absorbance signals from the reference dye solution and the dye filtrate solution are sent to a processor that compares the respective absorbances and calculates the protein content of the protein sample based upon the difference between the absorbances.Type: ApplicationFiled: June 29, 2015Publication date: October 22, 2015Applicant: CEM CORPORATIONInventors: Michael J. Collins, SR., Joseph J. Lambert, Timothy A. Zawatsky, David L. Herman
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Patent number: 9091632Abstract: A dye binding method for protein analysis is disclosed. The method includes the steps of preparing an initial reference dye solution of unknown concentration from an initial reference dye concentrate and creating an electronic signal based upon the absorbance of the initial reference dye solution. Thereafter, an electronic signal is created based upon the absorbance of a dye filtrate solution prepared from the initial reference dye solution and an initial protein sample. The absorbance signals from the reference dye solution and the dye filtrate solution are sent to a processor that compares the respective absorbances and calculates the protein content of the protein sample based upon the difference between the absorbances.Type: GrantFiled: September 27, 2013Date of Patent: July 28, 2015Assignee: CEM CorporationInventors: Michael J Collins, Sr., Joseph J Lambert, Timothy A Zawatsky, David L Herman
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Patent number: 8852948Abstract: A protein analysis instrument and method are disclosed. The method includes mixing a binding dye composition and a protein sample using a homogenizer, measuring a parameter selected from the group consisting of the speed of the homogenizer and the resistance of the mixture to the homogenizer, adjusting the speed of the homogenizer based upon the measured parameter, pumping unreacted dye composition from the mixture and to a calorimeter, and measuring the absorbance of the dye composition in the calorimeter. Aspects of the invention also include inserting a spout into a sample cup at a position where the spout opening is positioned to avoid foam and precipitate generated by the mixing step and above the bottom of the sample cup and thereafter pumping the dye composition from the mixture in the sample cup through the spout and to a colorimeter.Type: GrantFiled: August 4, 2008Date of Patent: October 7, 2014Assignee: CEM CorporationInventors: Michael J. Collins, Sr., Joseph J. Lambert, Timothy A. Zawatsky, David L. Herman
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Patent number: 8663993Abstract: A dye binding method for protein analysis is disclosed. The method includes the steps of preparing an initial reference dye solution of unknown concentration from an initial reference dye concentrate and creating an electronic signal based upon the absorbance of the initial reference dye solution. Thereafter, an electronic signal is created based upon the absorbance of a dye filtrate solution prepared from the initial reference dye solution and an initial protein sample. The absorbance signals from the reference dye solution and the dye filtrate solution are sent to a processor that compares the respective absorbances and calculates the protein content of the protein sample based upon the difference between the absorbances.Type: GrantFiled: March 11, 2010Date of Patent: March 4, 2014Assignee: CEM CorporationInventors: Michael J Collins, Sr., Joseph J Lambert, Timothy A Zawatsky, David L Herman
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Publication number: 20140024120Abstract: A dye binding method for protein analysis is disclosed. The method includes the steps of preparing an initial reference dye solution of unknown concentration from an initial reference dye concentrate and creating an electronic signal based upon the absorbance of the initial reference dye solution. Thereafter, an electronic signal is created based upon the absorbance of a dye filtrate solution prepared from the initial reference dye solution and an initial protein sample. The absorbance signals from the reference dye solution and the dye filtrate solution are sent to a processor that compares the respective absorbances and calculates the protein content of the protein sample based upon the difference between the absorbances.Type: ApplicationFiled: September 27, 2013Publication date: January 23, 2014Applicant: CEM Corp.Inventors: Michael J Collins, Sr., Joseph J Lambert, Timothy A Zawatsky, David L Herman
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Publication number: 20130265051Abstract: A method of measuring NMR response in an NMR instrument includes heating a sample at a heater temperature that is higher than the temperature of the interior of the NMR instrument, positioning the heated sample in the NMR instrument, and measuring the NMR response of the heat sample. Typically, the sample is dry and includes fat. Furthermore, a method of determining an amount of a component of a sample includes positioning a sample in an NMR instrument, applying a sequence of radio-frequency pulses to the sample, measuring the amplitudes of the signals produced by the application of the sequence of radio-frequency pulses, and determining the amount of a component in the sample using the measured amplitudes of the signals. The disclosed methods typically provide accurate analysis of samples in a shorter time period than traditional NMR techniques and solvent-based analysis techniques.Type: ApplicationFiled: April 9, 2013Publication date: October 10, 2013Inventors: Michael J. Collins, SR., Jonathan M. Collins, Colin L. Simpson
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Patent number: 8147759Abstract: A direct rapid automated protein analyzer is disclosed. The protein analyzer includes means for reducing protein samples to small particles, a reaction vessel in material transfer communication with the homogenizer, a reservoir for binding dye composition in fluid communication with the reaction vessel, a metering pump in fluid communication with the reservoir and the reaction vessel for distributing discrete predetermined amounts of a binding dye composition to the reaction vessel, a filter in fluid communication with the reaction vessel for separating solids from filtrate after a dye binding reaction has taken place in the reaction vessel, and a calorimeter in fluid communication with the filter and the reaction vessel for measuring the absorbance of the filtrate from the reaction vessel and the filter. The rapid analyzer can be used in conjunction with a kit that includes a sample cup for mixing a protein sample with a dye-binding solution and a filter holder for being positioned in the sample cup.Type: GrantFiled: August 29, 2007Date of Patent: April 3, 2012Assignee: CEM CorporationInventors: Michael J. Collins, Sr., Joseph J. Lambert, Timothy A. Zawatsky, David L. Herman