Patents by Inventor Michael J. Constant

Michael J. Constant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240108781
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Application
    Filed: October 6, 2023
    Publication date: April 4, 2024
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Patent number: 11801326
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Grant
    Filed: October 6, 2020
    Date of Patent: October 31, 2023
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Publication number: 20220273700
    Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Application
    Filed: May 13, 2022
    Publication date: September 1, 2022
    Inventors: Gregory M. Cruise, Michael J. Constant, Joshua Garretson
  • Patent number: 11331340
    Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: May 17, 2022
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Joshua Garretson
  • Patent number: 11160557
    Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: November 2, 2021
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Terrance Tran
  • Patent number: 10946100
    Abstract: Polymers are described herein comprising: a reaction product of a prepolymer solution including at least one macromer and at least one visualization agent; and an active agent electrostatically bound to the polymer filament or chemically bound to the at least one monomer; wherein the polymer filament does not include metallic support members.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: March 16, 2021
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Clayton G. Harris, Michael J. Constant
  • Publication number: 20210023261
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Application
    Filed: October 6, 2020
    Publication date: January 28, 2021
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Patent number: 10828388
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: November 10, 2020
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Publication number: 20200268789
    Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Application
    Filed: March 2, 2020
    Publication date: August 27, 2020
    Inventors: Gregory M. Cruise, Michael J. Constant, Joshua Garretson
  • Patent number: 10588923
    Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: March 17, 2020
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Joshua Garretson
  • Publication number: 20190192726
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Application
    Filed: February 27, 2019
    Publication date: June 27, 2019
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Publication number: 20190151452
    Abstract: Polymers are described herein comprising: a reaction product of a prepolymer solution including at least one macromer and at least one visualization agent; and an active agent electrostatically bound to the polymer filament or chemically bound to the at least one monomer; wherein the polymer filament does not include metallic support members.
    Type: Application
    Filed: January 17, 2019
    Publication date: May 23, 2019
    Inventors: Gregory M. Cruise, Clayton G. Harris, Michael J. Constant
  • Publication number: 20190150932
    Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.
    Type: Application
    Filed: January 17, 2019
    Publication date: May 23, 2019
    Inventors: Gregory M. Cruise, Michael J. Constant, Terrance Tran
  • Publication number: 20190134078
    Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Application
    Filed: December 26, 2018
    Publication date: May 9, 2019
    Inventors: Gregory M. Cruise, Michael J. Constant, Joshua Garretson
  • Patent number: 10258716
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: April 16, 2019
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Patent number: 10226258
    Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: March 12, 2019
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Terrance Tran
  • Patent number: 10226533
    Abstract: Polymers are described herein comprising: a reaction product of a prepolymer solution including at least one macromer and at least one visualization agent; and an active agent electrostatically bound to the polymer filament or chemically bound to the at least one monomer; wherein the polymer filament does not include metallic support members.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: March 12, 2019
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Clayton G. Harris, Michael J. Constant
  • Patent number: 10201562
    Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: February 12, 2019
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Joshua Garretson
  • Patent number: 10194915
    Abstract: Described are devices for implantation comprising a hydrogel filament wherein the hydrogel filament includes a low molecular weight ethylenically unsaturated macromer, an ethylenically unsaturated monomer, and a visualization agent. Methods of making and using these devices are also described.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: February 5, 2019
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Terrance T. Tran
  • Publication number: 20180200288
    Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Application
    Filed: March 16, 2018
    Publication date: July 19, 2018
    Inventors: Gregory M. Cruise, Michael J. Constant, Joshua Garretson