Patents by Inventor Michael J. Cooke

Michael J. Cooke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240067657
    Abstract: The present invention relates to novel Amido-Substituted Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R7, and R8 are as defined herein. The present invention also relates to compositions comprising at least one Amido-Substituted Heterocycle Compound, and methods of using the Amido-Substituted Heterocycle Compounds for treating or preventing a herpesvirus infection in a patient.
    Type: Application
    Filed: December 21, 2021
    Publication date: February 29, 2024
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Kira A. Armacost, Richard Thaddeus Berger, Jr., Andrew J. Cooke, Christopher Douglas Cox, Brendan M. Crowley, Marc Labroli, Michael Aaron Plotkin, Izzat Tiedje Raheem, Anthony W. Shaw, Kelly-Ann S. Schlegel, Jason W. Skudlarek, Ling Tong
  • Publication number: 20220249744
    Abstract: A method of reducing or limiting tissue adhesion comprises contacting the tissue with an effective amount of a hydrogel composition comprising: 2% to 6% by weight hyaluronan, and 3% to 18% by weight methylcellulose, wherein the combined total amount of hyaluronan and methylcellulose in the hydrogel is between 8 and 24% by weight; and wherein the ratio of hyaluronan:methylcellulose is between 1:1 and 1:5 w/w. The hydrogel composition and may be used to reduce or limit tissue adhesion that is correlated with surgery, and may be used in surgeries wherein the surgery is performed through a small incision or opening.
    Type: Application
    Filed: May 18, 2020
    Publication date: August 11, 2022
    Inventors: Molly SHOICHET, Michael J. COOKE
  • Publication number: 20220202793
    Abstract: A bioresorbable, sustained release pharmaceutical composition comprising: 1.8 wt % to 3.0 wt % methylcellulose and 0.1 wt % to 3.0 wt % hyaluronan in the form of a gel polymer matrix, and at least one local anesthetic agent, suitably ropivacaine, which may be administered by injection.
    Type: Application
    Filed: May 18, 2020
    Publication date: June 30, 2022
    Inventors: Molly SHOICHET, Michael J. COOKE, Sonja ING
  • Patent number: 10008369
    Abstract: There is provided an apparatus for cyclical plasma etching of a substrate, the apparatus comprising: a process chamber; a support within the process chamber for receiving the substrate to be etched; a controller for repeatedly applying a dosing step and a bombardment steps respectively; a dosing controller for controlling the flow of a process gas in the dosing step such that the substrate is exposed to a maximum dose of process gas in use of 1000 Langmuirs and said dose is controllable within an accuracy of 1 Langmuir; and a first signal generator coupled to the process chamber and a second signal generator coupled to the support within the process chamber, the first and second signal generators being configured such that in use positions ions of an plasma active species within the process chamber have a substrate bombardment energy in the range of 10 eV to 100 eV which is controllable within an accuracy of 5 eV. There is also provided a method for cyclical plasma etching of a substrate using said apparatus.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: June 26, 2018
    Assignee: Oxford Instruments Nanotechnology Tools Limited
    Inventors: Andrew L. Goodyear, Michael J. Cooke
  • Publication number: 20170069469
    Abstract: There is provided an apparatus for cyclical plasma etching of a substrate, the apparatus comprising: a process chamber; a support within the process chamber for receiving the substrate to be etched; a controller for repeatedly applying a dosing step and a bombardment steps respectively; a dosing controller for controlling the flow of a process gas in the dosing step such that the substrate is exposed to a maximum dose of process gas in use of 1000 Langmuirs and said dose is controllable within an accuracy of 1 Langmuir; and a first signal generator coupled to the process chamber and a second signal generator coupled to the support within the process chamber, the first and second signal generators being configured such that in use positions ions of an plasma active species within the process chamber have a substrate bombardment energy in the range of 10 eV to 100 eV which is controllable within an accuracy of 5 eV. There is also provided a method for cyclical plasma etching of a substrate using said apparatus.
    Type: Application
    Filed: August 26, 2016
    Publication date: March 9, 2017
    Inventors: Andrew L. GOODYEAR, Michael J. COOKE
  • Patent number: 5183402
    Abstract: An apparatus for supporting a workpiece has an enclosure, a means for reducing the pressure and a platen on which the workpiece is mounted. A heating mechanism is located within the platen and the platen is coated with a high emissivity material, which facilitates the radiative heat transfer between the platen and the workpiece. Consequently, the workpiece can be rapidly raised to a specific temperature. This apparatus is particularly applicable to the supporting of a semiconductor wafer within a vacuum system.
    Type: Grant
    Filed: May 14, 1991
    Date of Patent: February 2, 1993
    Assignee: Electrotech Limited
    Inventors: Michael J. Cooke, Arthur J. McGeown
  • Patent number: 4488506
    Abstract: An apparatus for depositing metal or alloy films by a thermal decomposition process on a substrate includes a furnace having a number of selectively heated zones. The temperature of each zone is controllable so as to provide compensation for changes in the concentration of reactant materials in the different regions of the furnace. Means are provided for the safe handling of highly pyrophoric organometallic reactants. The apparatus may be used for the deposition of aluminium/silicon alloy films on semiconductor wafers in the manufacture of integrated circuits.
    Type: Grant
    Filed: June 15, 1982
    Date of Patent: December 18, 1984
    Assignee: ITT Industries, Inc.
    Inventors: Rudolf A. H. Heinecke, Ronald C. Stern, Michael J. Cooke
  • Patent number: 4475931
    Abstract: This invention relates to a method for the production of gases free from particulate contaminants, for use in driving gas turbines without causing fouling or corrosion of the blading.The method comprises feeding a gas contaminated with particulate material, for instance produced by the combustion or gasification of coal, and a tackifying material, such as a crackable hydrocarbon or an inorganic compound, to a collection medium, preferably a fluidized particle bed, maintained at a temperature whereat the tackifying material becomes sticky and is deposited on the collection medium. The contaminants are removed by becoming stuck thereon.
    Type: Grant
    Filed: October 14, 1980
    Date of Patent: October 9, 1984
    Assignee: Coal Industry (Patents) Limited
    Inventors: Roland Clift, Mojtaba Ghadiri, Michael J. Cooke