Patents by Inventor Michael J. Cope
Michael J. Cope has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230405043Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: August 28, 2023Publication date: December 21, 2023Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
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Patent number: 11738041Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: GrantFiled: April 19, 2022Date of Patent: August 29, 2023Assignee: RENOSIS, INC.Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
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Publication number: 20220339186Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: April 19, 2022Publication date: October 27, 2022Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
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Patent number: 11406661Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: GrantFiled: May 5, 2017Date of Patent: August 9, 2022Assignee: TRICIDA, INC.Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
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Patent number: 11311571Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: GrantFiled: December 10, 2015Date of Patent: April 26, 2022Assignee: TRICIDA, INC.Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
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Publication number: 20220096534Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: December 9, 2021Publication date: March 31, 2022Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
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Publication number: 20220062328Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: September 24, 2021Publication date: March 3, 2022Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
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Patent number: 11197887Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: GrantFiled: August 16, 2019Date of Patent: December 14, 2021Assignee: TRICIDA, INC.Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
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Publication number: 20210205351Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: March 4, 2021Publication date: July 8, 2021Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
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Patent number: 10905711Abstract: The present invention provides methods and compositions for the treatment of ion imbalances using core-shell composites and compositions comprising such core-shell composites. In particular, the invention provides core-shell particles and compositions comprising potassium binding polymers, and core-shell particles and compositions comprising sodium binding polymers, and in each case, pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are also disclosed. The compositions and methods of the invention offer improved approaches for treatment of hyperkalemia and other indications related to potassium ion homeostasis, and for treatment of hypertension and other indicates related to sodium ion homeostasis.Type: GrantFiled: January 12, 2018Date of Patent: February 2, 2021Assignee: Vifor (International) Ltd.Inventors: Michael J. Cope, Paul Mansky, Futian Liu, Han-Ting Chang, Dominique Charmot, Eric Connor, Kalpesh Biyani, Mingjun Liu, Tony Kwok-Kong Mong, Yan Chen
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Publication number: 20200206260Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: August 16, 2019Publication date: July 2, 2020Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
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Publication number: 20200054669Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: May 5, 2017Publication date: February 20, 2020Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
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Patent number: 10391118Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: GrantFiled: June 7, 2018Date of Patent: August 27, 2019Assignee: TRICIDA, INCInventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
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Patent number: 10369169Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: GrantFiled: April 4, 2019Date of Patent: August 6, 2019Assignee: TRICIDA, INC.Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
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Publication number: 20190231812Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: April 4, 2019Publication date: August 1, 2019Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
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Patent number: 10363268Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: GrantFiled: June 7, 2018Date of Patent: July 30, 2019Assignee: TRICIDA, INC.Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
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Publication number: 20190209607Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: May 5, 2017Publication date: July 11, 2019Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
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Publication number: 20190134076Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: May 5, 2017Publication date: May 9, 2019Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
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Publication number: 20190134075Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: June 7, 2018Publication date: May 9, 2019Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
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Publication number: 20180280428Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.Type: ApplicationFiled: June 7, 2018Publication date: October 4, 2018Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN