Patents by Inventor Michael J. Dart

Michael J. Dart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF
    Publication number: 20100093814
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, R4, and L1 are defined in the specfication, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. The present invention also relates to compounds of formula (II), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1a, R2a, Rx, and n are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: November 19, 2008
    Publication date: April 15, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Alan S. Florjancic, Michael J. Dart, Keith B. Ryther, Arturo Perez-Medrano, William A. Carroll, Meena V. Patel, Karin Rosemarie Tietje, Tongmei Li, Teodozyj Kolasa, Megan E. Gallagher, Sridhar Peddi, Jennifer M. Frost, Derek W. Nelson
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20100069348
    Abstract: Disclosed herein are cannabinoid receptor ligands of formula (I) wherein A1, A5, Rx, X4, and z are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
    Type: Application
    Filed: September 16, 2009
    Publication date: March 18, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: William A. Carroll, Michael J. Dart, Jennifer M. Frost, Steven P. Latshaw, Teodozyj Kolasa, Tongmei Li, Sridhar Peddi, Bo Liu, Arturo Perez-Medrano, Meena Patel, Xueqing Wang, Derek W. Nelson
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20100069349
    Abstract: Disclosed herein are cannabinoid receptor ligands of formula (I) wherein A1, A5, Rx, X4, and z are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
    Type: Application
    Filed: September 16, 2009
    Publication date: March 18, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: William A. Carroll, Michael J. Dart, Jennifer M. Frost, Steven P. Latshaw, Teodozyj Kolasa, Tongmei Li, Sridhar Peddi, Bo Liu, Arturo Perez-Medrano, Meena Patel, Xueqing Wang, Derek W. Nelson
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20100063022
    Abstract: The present application relates to cannabinoid receptor ligands of formula (I) wherein X1, A1, Rx, R2, R3, R4, and z are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: September 4, 2009
    Publication date: March 11, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: William A. Carroll, Michael J. Dart, Jennifer M. Frost, Teodozyj Kolasa, Tongmei Li, Bo Liu, Arturo Perez-Medrano, Meena Patel, Xueqing Wang, Sridhar Peddi
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20100041720
    Abstract: Disclosed herein are cannabinoid receptor ligands of formula (I) wherein Y, X1, X2, X3, R1, and R2 are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
    Type: Application
    Filed: August 11, 2009
    Publication date: February 18, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: William A. Carroll, Michael J. Dart, Jennifer M. Frost, Teodozyj Kolasa, Steven P. Latshaw, Bo Liu, Meena V. Patel, Arturo Perez-Medrano, Xueqing Wang
  • Indoles are cannabinoid receptor ligands
    Patent number: 7560481
    Abstract: The present invention provides novel compounds of Formula (I) which are CB2 selective ligands useful for the treatment of pain.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: July 14, 2009
    Assignee: Abbott Laboratories
    Inventors: Jennifer M. Frost, Karin R. Tietje, Michael J. Dart, Michael D. Meyer
  • NOVEL INDOLES ARE CANNABINOID RECEPTOR LIGANDS
    Publication number: 20090149501
    Abstract: The present invention provides novel compounds of Formula (I) which are CB2 selective ligands useful for the treatment of pain.
    Type: Application
    Filed: February 13, 2009
    Publication date: June 11, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Jennifer M. Frost, Karin R. Tietje, Michael J. Dart, Michael D. Meyer
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20090105306
    Abstract: The present invention relates compounds of formula (I) wherein A and R1 are as defined in the specification, pharmaceutical compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and pharmaceutical compositions.
    Type: Application
    Filed: October 7, 2008
    Publication date: April 23, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: William A. Carroll, Michael J. Dart, Arturo Perez-Medrano, Derek W. Nelson, Tongmei Li, Sridhar Peddi, Jennifer Frost, Teodozyj Kolasa, Bo Liu, Steven P. Latshaw, Xueqing Wang
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20090023789
    Abstract: The present application relates to isothiazolylidene containing compounds of Formula (I) wherein R1, R2, R3, R4, and L are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: April 10, 2008
    Publication date: January 22, 2009
    Applicant: Abbott Laboratories
    Inventors: William A. Carroll, Michael J. Dart, Teodozyj Kolasa, Tongmei Li, Derek W. Nelson, Meena V. Patel, Sridhar Peddi, Arturo Perez-Medrano, Xueqing Wang
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20090018114
    Abstract: The present application relates to cannabinoid receptor ligands containing compounds of formula (I) wherein A, R1, R2, and R3 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: July 8, 2008
    Publication date: January 15, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: William A. Carroll, Michael J. Dart, Arturo Perez-Medrano, Derek W. Nelson
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20080287510
    Abstract: The present application relates to thiazolylidene containing compounds of formula (I) wherein R1, R2, R3, and R4 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: May 15, 2008
    Publication date: November 20, 2008
    Applicant: Abbott Laboratories
    Inventors: William A. Carroll, Michael J. Dart, Arturo Perez-Medrano, Jennifer M. Frost, Sridhar Peddi
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20080255123
    Abstract: The present invention relates to compounds of formula (I) wherein A, E, L2, R1, R3, R4 and R5 are as defined in the herein, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: October 12, 2007
    Publication date: October 16, 2008
    Applicant: Abbott Laboratories
    Inventors: Michael D. Meyer, Michael J. Dart, William A. Carroll, Meena V. Patel, Tedozyi Kolasa, Xueqing Wang
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20080242654
    Abstract: The present application relates to thiazolylidene containing compounds of formula (I) wherein R1, R2, R3, R4, L2 and A are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
    Type: Application
    Filed: March 19, 2008
    Publication date: October 2, 2008
    Applicant: ABBOTT LABORATORIES
    Inventors: Teodozyj Kolasa, Jennifer M. Frost, Meena V. Patel, Steven P. Latshaw, Arturo Perez-Medrano, Xueqing Wang, Sridhar Peddi, William A. Carroll, Michael J. Dart
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF
    Publication number: 20080153883
    Abstract: The present invention relates to thiazolidinylidene containing compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, and X are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: December 12, 2007
    Publication date: June 26, 2008
    Applicant: ABBOTT LABORATORIES
    Inventors: William A. Carroll, Michael J. Dart, Tongmei Li, Arturo V. Perez-Medrano, Sridhar Peddi
  • Diazabicyclic CNS active agents
    Patent number: 7265115
    Abstract: Compounds of formula I: or pharmaceutically acceptable salts thereof, are useful for controlling synaptic transmission in mammals.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: September 4, 2007
    Assignee: Abbott Laboratories
    Inventors: William H. Bunnelle, Daniela Barlocco Cristina, Jerome F. Daanen, Michael J. Dart, Michael D. Meyer, Keith B. Ryther, Michael R. Schrimpf, Kevin B. Sippy, Richard B. Toupence
  • Azabicyclic compounds are central nervous system active agents
    Patent number: 7135484
    Abstract: Compounds of formula (I) are novel CNS active agents that are useful for treating pain and for treating other disorders associated with the cholinergic system.
    Type: Grant
    Filed: August 12, 2003
    Date of Patent: November 14, 2006
    Assignee: Abbott Laboratories
    Inventors: Michael J. Dart, Xenia B. Searle, Karin R. Tietje, Richard B. Toupence
  • Fused cycloalkyl amides and acids and their therapeutic applications
    Publication number: 20040209859
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: October 22, 2003
    Publication date: October 21, 2004
    Inventors: Youssef L. Bennani, Sou-Jen Chang, Sanjay R. Chemburkar, Michael J. Dart, Dilinie P. Fernando, Timothy A. Grieme
  • Cycloalkylamides and their therapeutic applications
    Publication number: 20040209858
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: October 22, 2003
    Publication date: October 21, 2004
    Inventors: Youssef L. Bennani, Steve A. Chamberlin, Sanjay R. Chemburkar, Jinhua Chen, Michael J. Dart, Ashok K. Gupta, Lei Wang
  • Spirocyclopropyl amides and acids and their therapeutic applications
    Publication number: 20040204396
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: October 22, 2003
    Publication date: October 14, 2004
    Inventors: Youseff L. Bennani, William H. Bunnelle, Sou-Jen Chang, Sanjay R. Chemburkar, Jinhua Chen, Michael J. Dart, Dilinie Fernando, Yi-Yin Ku, Mark Lockwood, Lei Wang
  • Azabicyclic compounds are central nervous system active agents
    Publication number: 20040152724
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: August 12, 2003
    Publication date: August 5, 2004
    Inventors: Michael J. Dart, Xenia B. Searle, Karin R. Tietje, Richard B. Toupence