Patents by Inventor Michael J. Demeure

Michael J. Demeure has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and kits used in classifying adrenocortical carcinoma
    Patent number: 10066270
    Abstract: The invention encompasses methods and kits used to detect biomarkers that may be used to predict disease outcome in adrenocortical carcinoma patients.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: September 4, 2018
    Assignee: The Translational Genomics Research Institute
    Inventors: Kimberly J. Bussey, Michael J. Demeure
  • Systems and methods for diagnosing and treating cancer
    Patent number: 9745634
    Abstract: This invention identifies and provides a recurrent translocation t(4;8) (p16.2; p23.1) associated with certain cancers and other abnormal cell growth disorders and diagnostic methods using the translocation by FISH hybridization or PCR based assays.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: August 29, 2017
    Assignee: The Translational Genomics Research Institute
    Inventors: Kimberly Bussey, Michael J. Demeure
  • METHODS AND KITS USED IN CLASSIFYING ADRENOCORTICAL CARCINOMA
    Publication number: 20170226592
    Abstract: The invention encompasses methods and kits used to detect biomarkers that may be used to predict disease outcome in adrenocortical carcinoma patients.
    Type: Application
    Filed: April 18, 2017
    Publication date: August 10, 2017
    Inventors: Kimberly J. Bussey, Michael J. Demeure
  • METHODS FOR THE TREATMENT OF CANCER
    Publication number: 20160038498
    Abstract: The present invention is directed to methods for treating cancer in a subject, such as a cancer of the endocrine system. In some aspects, the method includes administering to the subject one or more of a polo-like kinase 1 inhibitor, a mouse double minute 2 inhibitor, and/or a mitotic catastrophe inducing compound. In other aspects, the method includes measuring an expression level of one or more markers, including caspase 8 and caspase 9, to assess the functionality of the caspase cascade in the subject.
    Type: Application
    Filed: October 23, 2015
    Publication date: February 11, 2016
    Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
    Inventors: Kimberly J. Bussey, Michael J. Demeure, Aditi Bapat
  • Therapeutic targets for adrenocortical carcinoma
    Patent number: 9222138
    Abstract: This invention identifies and provides a recurrent translocation t(4;8) (p16.2; p23.1) associated with Adrenocortical Carcinoma, and diagnostic methods using the translocation by FISH hybridization or PCR based assays.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: December 29, 2015
    Assignees: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE, SCOTTSDALE HEALTHCARE CORPORATION
    Inventors: Kimberly Bussey, Michael J. Demeure
  • Methods for the treatment of cancer
    Patent number: 9198910
    Abstract: The present invention is directed to methods for treating cancer in a subject, such as a cancer of the endocrine system. In some aspects, the method includes administering to the subject one or more of a polo-like kinase 1 inhibitor, a mouse double minute 2 inhibitor, and/or a mitotic catastrophe inducing compound. In other aspects, the method includes measuring an expression level of one or more markers, including caspase 8 and caspase 9, to assess the functionality of the caspase cascade in the subject.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: December 1, 2015
    Assignee: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
    Inventors: Kimberly J. Bussey, Michael J. Demeure, Aditi Bapat
  • METHODS AND KITS USED IN CLASSIFYING ADRENOCORTICAL CARCINOMA
    Publication number: 20150329916
    Abstract: The invention encompasses methods and kits used to detect biomarkers that may be used to predict disease outcome in adrenocortical carcinoma patients.
    Type: Application
    Filed: July 23, 2015
    Publication date: November 19, 2015
    Inventors: Kimberly Bussey, Michael J. Demeure
  • SYSTEMS AND METHODS FOR DIAGNOSING AND TREATING CANCER
    Publication number: 20150072348
    Abstract: This invention identifies and provides a recurrent translocation t(4;8) (p16.2; p23.1) associated with certain cancers and other abnormal cell growth disorders and diagnostic methods using the translocation by FISH hybridization or FOR based assays.
    Type: Application
    Filed: November 20, 2014
    Publication date: March 12, 2015
    Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
    Inventors: Kimberly Bussey, Michael J. Demeure
  • METHODS FOR THE TREATMENT OF CANCER
    Publication number: 20140303120
    Abstract: The present invention is directed to methods for treating cancer in a subject, such as a cancer of the endocrine system. In some aspects, the method includes administering to the subject one or more of a polo-like kinase 1 inhibitor, a mouse double minute 2 inhibitor, and/or a mitotic catastrophe inducing compound. In other aspects, the method includes measuring an expression level of one or more markers, including caspase 8 and caspase 9, to assess the functionality of the caspase cascade in the subject.
    Type: Application
    Filed: April 4, 2014
    Publication date: October 9, 2014
    Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
    Inventors: Kimberly J. Bussey, Michael J. Demeure, Aditi Bapat