Abstract: A representative method for coordinating and optimizing resources in the completion of a set of tasks includes providing multiple task types defined for a scenario and task priorities; combining multiple solutions of the respective multiple task types into multiple candidate decisions; determining candidate scores for the respective multiple candidate decisions based on the combined multiple solutions of the respective multiple task types; determining an optimal candidate score based on the candidate scores from the respective multiple candidate decisions and task priorities; and selecting an optimal response to a given scenario based on the candidate decision based on having the determined optimal candidate score.

Abstract: In some embodiments, the present invention provides methods of detecting a molecule in a sample, such as an explosive. In some embodiments, the method comprises: associating the sample with an antigen/binding agent complex; measuring a rate of displacement of the binding agent from the antigen by the molecule in the sample; and correlating the measured rate of displacement to the presence of the molecule in the sample. In some embodiments, the measuring step comprises a determination of a change in frequency of the sample and a change in energy dissipation of the sample over a time interval. In some embodiments, the correlating step comprises a calculation of a ratio of a change in energy dissipation of the sample over a change in frequency of the sample over the time interval. In some embodiments, the method is used to determine the molecule concentration in the sample.