Abstract: An ergonomic and unobtrusive cardiac monitoring and treatment device for continuous wear includes a band configured to be worn about a thoracic region of a patient within a T1 thoracic vertebra region to a T12 thoracic vertebra region. The band includes a vertical span of between 1 to 15 centimeters along at least 50 percent of a length of the band and is configured to be immobilized relative to a skin surface of the thoracic region by exerting one or more compression forces. The device also includes electrodes and associated circuitry disposed about the band, one or more sensor ports for receiving one or more physiological sensors separate from ECG sensing electrodes, and a controller. The controller includes an ingress-protected housing and a processor configured to analyze ECG information of the patient, detect one or more treatable arrhythmias based on the ECG information, and cause delivery of electrotherapy.

Abstract: A cardiac monitoring and treatment system includes a controller, a first wearable portion, and a second wearable portion separate from the first wearable portion. The first wearable portion includes an elongated strap configured to encircle a thoracic region of a patient, a plurality of ECG sensing electrodes disposed about the elongated strap, one or more receiving ports configured to receive one or more additional components including a treatment electrode and/or an additional sensor, and a plurality of conductive wires configured to couple the plurality of ECG sensing electrodes and the one or more receiving ports with the controller. The second wearable portion is configured to be worn over at least one shoulder of the patient and includes a wearable substrate, one or more treatment electrodes disposed on the wearable substrate, and at least one conductive wire configured to releasably connect the one or more treatment electrodes to the controller.

Abstract: A cardiac monitoring and treatment system includes a controller, a first wearable portion, and a second wearable portion separate from the first wearable portion. The first wearable portion includes an elongated strap configured to encircle a thoracic region of a patient, a plurality of ECG sensing electrodes disposed about the elongated strap, one or more receiving ports configured to receive one or more additional components including a treatment electrode and/or an additional sensor, and a plurality of conductive wires configured to couple the plurality of ECG sensing electrodes and the one or more receiving ports with the controller. The second wearable portion is configured to be worn over at least one shoulder of the patient and includes a wearable substrate, one or more treatment electrodes disposed on the wearable substrate, and at least one conductive wire configured to releasably connect the one or more treatment electrodes to the controller.

Abstract: An ergonomic and unobtrusive cardiac monitoring and treatment device for continuous wear includes a band, ECG sensing electrodes and treatment electrodes configured to deliver an electrotherapy, one or more sensor ports for receiving one or more physiological sensors, and a controller for analyzing an ECG signal of a patient and causing a delivery of electro therapy. The band is configured to be worn about a thoracic region and has a vertical span of between about 1 to about 15 centimeters. The band is configured to be immobilized relative to a skin surface of the thoracic region of the patient by exerting one or more compression forces against the thoracic region. The device can include at least two separate wearable portions comprising a band portion including ECG sensing electrodes and/or other physiological sensors, and a second wearable portion optionally separable from the band portion, the second wearable portion including treatment electrodes.

Abstract: An ergonomic and unobtrusive cardiac monitoring and treatment device for continuous wear includes a band, ECG sensing electrodes and treatment electrodes configured to deliver an electrotherapy, one or more sensor ports for receiving one or more physiological sensors, and a controller for analyzing an ECG signal of a patient and causing a delivery of electro therapy. The band is configured to be worn about a thoracic region and has a vertical span of between about 1 to about 15 centimeters. The band is configured to be immobilized relative to a skin surface of the thoracic region of the patient by exerting one or more compression forces against the thoracic region. The device can include at least two separate wearable portions comprising a band portion including ECG sensing electrodes and/or other physiological sensors, and a second wearable portion optionally separable from the band portion, the second wearable portion including treatment electrodes.

Abstract: The present invention provides methods for predicting or modeling a chemotherapy outcome for a given patient, to assist physicians in the selection of chemotherapeutic agents for individualized cancer treatment.