Patents by Inventor Michael J. Gumkowski

Michael J. Gumkowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUG AND NEUTRAL POLYMERS
    Publication number: 20160374945
    Abstract: In one aspect, pharmaceutical compositions comprising dispersions of an acid-sensitive drug and a neutral dispersion polymer are disclosed. The acid-sensitive drug has improved chemical stability relative to dispersions of the drug and acidic polymers. In another aspect, pharmaceutical compositions of low-solubility drugs and amphiphilic, hydroxy-functional vinyl copolymers are disclosed.
    Type: Application
    Filed: September 7, 2016
    Publication date: December 29, 2016
    Applicant: Bend Research, Inc.
    Inventors: Dwayne T. Friesen, Michael J. Gumkowski, Rodney James Ketner, Douglas A. Lorenz, James A. S. Nightingale, Ravi M. Shanker, James B. West
  • Pharmaceutical compositions of dispersions of drug and neutral polymers
    Patent number: 9468604
    Abstract: In one aspect, pharmaceutical compositions comprising dispersions of an acid-sensitive drug and a neutral dispersion polymer are disclosed. The acid-sensitive drug has improved chemical stability relative to dispersions of the drug and acidic polymers. In another aspect, pharmaceutical compositions of low-solubility drugs and amphiphilic, hydroxy-functional vinyl copolymers are disclosed.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: October 18, 2016
    Assignee: Bend Research, Inc.
    Inventors: Dwayne T. Friesen, Michael J. Gumkowski, Rodney James Ketner, Douglas A. Lorenz, James A. S. Nightingale, Ravi M. Shanker, James B. West
  • PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUG AND NEUTRAL POLYMERS
    Publication number: 20140210117
    Abstract: In one aspect, pharmaceutical compositions comprising dispersions of an acid-sensitive drug and a neutral dispersion polymer are disclosed. The acid-sensitive drug has improved chemical stability relative to dispersions of the drug and acidic polymers. In another aspect, pharmaceutical compositions of low-solubility drugs and amphiphilic, hydroxy-functional vinyl copolymers are disclosed.
    Type: Application
    Filed: April 1, 2014
    Publication date: July 31, 2014
    Applicant: BEND RESEARCH, INC.
    Inventors: Dwayne T. Friesen, Michael J. Gumkowski, Rodney James Ketner, Douglas A. Lorenz, James A. S. Nightingale, Ravi M. Shanker, James B. West
  • Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors
    Patent number: 8197848
    Abstract: A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer.
    Type: Grant
    Filed: April 30, 2007
    Date of Patent: June 12, 2012
    Assignee: Bend Research, Inc.
    Inventors: Marshall D. Crew, William J. Curatolo, Dwayne T. Friesen, Michael J. Gumkowski, Douglas A. Lorenz, James A. S. Nightingale, Roger B. Ruggeri, Ravi M. Shanker
  • Pharmaceutical compositions of cholesteryl ester transfer protein inhibitor
    Patent number: 8048452
    Abstract: A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: November 1, 2011
    Assignee: Bend Research, Inc.
    Inventors: William J. Curatolo, Dwayne T. Friesen, Michael J. Gumkowski, Douglas A. Lorenz, James A. S. Nightingale, Roger B. Ruggeri, Ravi M. Shanker
  • Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors
    Patent number: 7115279
    Abstract: A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: October 3, 2006
    Inventors: William J. Curatolo, Dwayne T. Friesen, Michael J. Gumkowski, Douglas A. Lorenz, James A. S. Nightingale, Roger B. Ruggeri, Ravi M. Shanker
  • Self-emulsifying formulations of cholesteryl ester transfer protein inhibitors
    Patent number: 6962931
    Abstract: CETP Inhibitors have improved solubility and bioavailability in a lipophilic vehicle comprising a digestible oil, a lipophilic solvent, or a surfactant. Preferred such compositions are self-emulsifying or self-microemulsifying, and comprise 1. a CETP inhibitor; 2. a cosolvent; 3. a surfactant having an HLB of 1 to 8; 4. a surfactant having an HLB of over 8 to 20; and 5. optionally, a digestible oil.
    Type: Grant
    Filed: June 19, 2002
    Date of Patent: November 8, 2005
    Assignee: Pfizer Inc.
    Inventors: Michael J. Gumkowski, Lombardo Franco, Sharad B. Murdande, Michael E. Perlman
  • Pharmaceutical compositions of dispersions of drugs and neutral polymers
    Publication number: 20030091643
    Abstract: In one aspect, pharmaceutical compositions comprising dispersions of an acid-sensitive drug and a neutral dispersion polymer are disclosed. The acid-sensitive drug has improved chemical stability relative to dispersions of the drug and acidic polymers. In another aspect, pharmaceutical compositions of low-solubility drugs and amphiphilic, hydroxy-functional vinyl copolymers are disclosed.
    Type: Application
    Filed: June 18, 2002
    Publication date: May 15, 2003
    Inventors: Dwayne T. Friesen, Michael J. Gumkowski, Rodney J. Ketner, Douglas A. Lorenz, James A. S. Nightingale, Ravi M. Shanker, James B. West
  • Self-emulsifying formulations of cholesteryl ester transfer protein inhibitors
    Publication number: 20030022944
    Abstract: CETP Inhibitors have improved solubility and bioavailability in a lipophilic vehicle comprising a digestible oil, a lipophilic solvent, or a surfactant.
    Type: Application
    Filed: June 19, 2002
    Publication date: January 30, 2003
    Inventors: Michael J. Gumkowski, Lombardo Franco, Sharad B. Murdande, Michael E. Perlman
  • Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors
    Publication number: 20020103225
    Abstract: A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer.
    Type: Application
    Filed: July 30, 2001
    Publication date: August 1, 2002
    Inventors: William J. Curatolo, Dwayne T. Friesen, Michael J. Gumkowski, Douglas A. Lorenz, James A. S. Nightingale, Roger B. Ruggeri, Ravi M. Shanker