Patents by Inventor Michael J. Iammarino

Michael J. Iammarino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL PROCESSES FOR PREPARING CONJUGATES OF THE IL-2 PROTEIN
    Publication number: 20230272001
    Abstract: Disclosed herein are novel processes for preparing IL-2 conjugates with one or more water-soluble polymers. In one embodiment, the IL-2 conjugate comprises five poly(ethylene glycol) polymers each of which is covalently attached to the IL-2 moiety via a releasable linkage to an amino group of the IL-2 moiety.
    Type: Application
    Filed: May 17, 2021
    Publication date: August 31, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Joshua Lee, Gregory F. Pirrone, Michael J. Iammarino, David J. Roush
  • Process for preparing recombinant insulin using microfiltration
    Patent number: 10562951
    Abstract: The use of two tandem microfiltration (MF) steps in a process for making recombinant insulin is described. The two MF steps in a single downstream purification unit operation reduce both soluble and insoluble impurities and exchange the insulin product into a suitable buffer for downstream purification.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: February 18, 2020
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Sean S. Gant, Michael J. Iammarino, Kristi Kerchner, Michael A. Rauscher, David J. Roush, Christopher H. Smith, Martin Chandler, Matthew Petroff
  • PROCESS FOR PREPARING RECOMBINANT INSULIN USING MICROFILTRATION
    Publication number: 20180044395
    Abstract: The use of two tandem microfiltration (MF) steps in a process for making recombinant insulin is described. The two MF steps in a single downstream purification unit operation reduce both soluble and insoluble impurities and exchange the insulin product into a suitable buffer for downstream purification.
    Type: Application
    Filed: March 3, 2016
    Publication date: February 15, 2018
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Sean S. Gant, Michael J. Iammarino, Kristi Kerchner, Michael A. Rauscher, David J. Roush, Christopher H. Smith, Martin Chandler, Matthew Petroff