Patents by Inventor Michael J. Imperiale

Michael J. Imperiale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Replication deficient adenovirus vectors and methods of making and using them
    Patent number: 6867022
    Abstract: The invention provides novel replication deficient adenovirus vectors and methods for making and using these viruses. The invention also provides vector systems and kits using a serotype specific strategy for making adenoviral vector preparations substantially free of replication competent “helper” virus. The helper virus-free preparations provide novel pharmaceutical compositions substantially free of helper virus for use in gene transfer and gene therapy.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: March 15, 2005
    Assignee: Regents of the University of Michigan
    Inventor: Michael J. Imperiale
  • Novel replication deficient adenovirus vectors and methods for making and using them
    Publication number: 20020187128
    Abstract: The invention provides novel replication deficient adenovirus vectors and methods for making and using these viruses. The invention also provides vector systems and kits using a serotype specific strategy for making adenoviral vector preparations substantially free of replication competent “helper” virus. The helper virus-free preparations provide novel pharmaceutical compositions substantially free of helper virus for use in gene transfer and gene therapy.
    Type: Application
    Filed: April 29, 2002
    Publication date: December 12, 2002
    Applicant: University of Michigan
    Inventor: Michael J. Imperiale