Patents by Inventor Michael J. Kinch

Michael J. Kinch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EPHA2 T-CELL EPITOPE AGONISTS AND USES THEREFORE
    Publication number: 20240101625
    Abstract: EphA2 T-cell epitope are provided herein. The epitopes include peptides corresponding to specific fragments of human EphA2 protein containing one or more T-cell epitopes, and conservative derivatives thereof. The EphA2 T-cell epitopes are useful in an assay, such as an ELISPOT assay, that may be used to determine and/or quantify a patient's immune responsiveness to EphA2. The epitopes also are useful in methods of modulating a patient's immune reactivity to EphA2, which has substantial utility as a treatment for cancers that overexpress EphA2, such as renal cell carcinoma (RCC). The EphA2 epitopes also can be used to vaccinate a patient against EphA2, by in vivo or ex vivo methods.
    Type: Application
    Filed: September 6, 2023
    Publication date: March 28, 2024
    Applicant: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Walter J. Storkus, Michael S. Kinch
  • Process for preparing test elements
    Patent number: 6093546
    Abstract: The invention relates to a process for making a test element, such as an analytical test element. Compositions of matter, such as analyte specific receptors, are treated to carry a charge. These are then applied to test carriers treated to carry a charge opposite that of the composition of matter. Interaction of charge fixes the composition of matter to the test element.
    Type: Grant
    Filed: September 3, 1992
    Date of Patent: July 25, 2000
    Assignee: Roche Diagnostics
    Inventors: David J. Ledden, David R. Moorman, Michael J. Kinch, Harvey B. Buck