Patents by Inventor Michael J. Konkel

Michael J. Konkel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of GAL3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods
    Publication number: 20090318504
    Abstract: This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
    Type: Application
    Filed: December 15, 2008
    Publication date: December 24, 2009
    Inventors: Thomas P. Blackburn, Michael J. Konkel, Lakmal W. Boteju, Ian Jamie Talisman, John M. Wetzel, Mathivanan Packiarajan, Heidi Chen, Hermo Jimenez
  • Use of GAL3 antagonist for treatment of depression and/or anxiety and compounds useful in such methods
    Patent number: 7465750
    Abstract: This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: December 16, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Thomas P. Blackburn, Michael J. Konkel, Lakmal W. Boteju, Ian Jamie Talisman, John M. Wetzel, Mathivanan Packiarajan, Heidi Chen, Hermo Jimenez
  • Use of GAL3 antagonist for treatment of depression
    Publication number: 20040127502
    Abstract: This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
    Type: Application
    Filed: November 26, 2003
    Publication date: July 1, 2004
    Applicant: Synaptic Pharmaceutical Corporation
    Inventors: Thomas P. Blackburn, Michael J. Konkel, Lakmal W. Boteju, Ian Jamie Talisman, John M. Wetzel, Mathivana Packiarajan, Heidi Chen, Hermo Jimenez
  • GAL3 receptor antagonists for the treatment of affective disorders
    Publication number: 20040110821
    Abstract: This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. This invention provides a method of treating a subject suffering from an affective disorder which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's affective disorder. This invention also provides a method of treating an affective disorder in a subject which comprises administering to the subject a composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a GAL3 receptor antagonist. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: August 7, 2003
    Publication date: June 10, 2004
    Inventors: Michael J. Konkel, Thomas P. Blackburn, John M. Wetzel
  • Compounds for the treatment of pain
    Publication number: 20030176314
    Abstract: This invention provides methods of treating pain, urinary incontinence and other abnormalities mediated by a NPFF receptor, which comprises administering to a subject a therapeutically effective amount of a chemical compound which acts at the NPFF1 receptor, the NPFF2 receptor, or at both the NPFF1 and NPFF2 receptors.
    Type: Application
    Filed: September 24, 2002
    Publication date: September 18, 2003
    Inventors: Carlos C. Forray, Joel Kawakami, Michael J. Konkel, Lakmal W. Boteju, John M. Wetzel, Stewart A. Noble, Honghe Wan
  • Molecules specific for NPFF receptors and uses thereof
    Publication number: 20030144310
    Abstract: This invention provides a compound having the structure: 1
    Type: Application
    Filed: September 24, 2002
    Publication date: July 31, 2003
    Inventors: Lakmal W. Boteju, Michael J. Konkel, Joel K. Kawakami, John Wetzel
  • Guanidines which are agonist/antagonist ligands for neuropeptide FF (NPFF) receptors
    Publication number: 20030139431
    Abstract: This invention provides compounds having the structure: 1
    Type: Application
    Filed: September 21, 2002
    Publication date: July 24, 2003
    Inventors: Joel K. Kawakami, John Wetzel, Lakmal W. Boteju, Michael J. Konkel, Honghe Wan, Stewart A. Noble
  • Use of GAL3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods
    Publication number: 20030078271
    Abstract: This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
    Type: Application
    Filed: January 31, 2002
    Publication date: April 24, 2003
    Inventors: Thomas P. Blackburn, Michael J. Konkel, Lakmal W. Boteju, Ian Jamie Talisman, John M. Wetzel, Mathivanan Packiarajan, Heidi Chen, Hermo Jimenez