Patents by Inventor Michael J. Loughran

Michael J. Loughran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240076291
    Abstract: The present invention relates to compounds of Formula (I): and pharmaceutically acceptable salts or prodrug thereof. The present invention also relates to compositions comprising at least one compound of Formula (I), and methods of using the compounds of Formula (I) for treatment or prophylaxis of lysosomal storage diseases, neurodegenerative disease, cystic disease, cancer, or a diseases or disorders associated with elevated levels of glucosylceramide (GlcCer), glucosylsphingosine (GlcSph) and/or other glucosylceramide-based glycosphingolipids (GSLs).
    Type: Application
    Filed: November 18, 2021
    Publication date: March 7, 2024
    Applicant: MERCK SHARP & DOHME LLC
    Inventors: Michael J. Breslin, Mark E. Fraley, H. Marie Loughran, James J. Mulhearn, Anthony J. Roecker, Kathy M. Schirripa, Shawn J. Stachel
  • Patent number: 10733175
    Abstract: This invention relates to a system, method and computer program product for a data warehouse model validation system, said data warehouse model validation system having an ETL model and a corresponding data warehouse model, said data ETL system comprising: an element group locator for locating an element group across the ETL model and the data warehouse model, whereby the element group comprises ETL elements and related data warehouse elements; an inconsistency determiner for determining inconsistencies between the ETL elements and data warehouse elements, whereby one or more elements are missing from the data warehouse model or one or more elements in the data warehouse model do not correspond to expected elements or features of elements; and an inconsistency recorder for recording any located missing elements or unexpected elements from the located element group.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: August 4, 2020
    Assignee: International Business Machines Corporation
    Inventors: Gary Denner, Paul Kilroy, Michael J. Loughran
  • Patent number: 10585875
    Abstract: This invention relates to a system, method and computer program product for a data warehouse model validation system, said data warehouse model validation system having an ETL model and a corresponding data warehouse model, said data ETL system comprising: an element group locator for locating an element group across the ETL model and the data warehouse model, whereby the element group comprises ETL elements and related data warehouse elements; an inconsistency determiner for determining inconsistencies between the ETL elements and data warehouse elements, whereby one or more elements are missing from the data warehouse model or one or more elements in the data warehouse model do not correspond to expected elements or features of elements; and an inconsistency recorder for recording any located missing elements or unexpected elements from the located element group.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: March 10, 2020
    Assignee: International Businses Machines Corporation
    Inventors: Gary Denner, Paul Kilroy, Michael J. Loughran
  • Patent number: 9946989
    Abstract: Techniques are disclosed for managing development of a model set comprised of one or more object models by a plurality of model developers. Each model developer may be considered an interested party. For example, when a model developer changes an area of the model, that person becomes the most interested party in other changes made to the same area. An automated mechanism is provided to track changes made to the model set and informs interested parties as changes are made or after changes are made to the model based on a weighting system. In one embodiment, the weighting system may be based on a distance from the changed portions and on the amount of time since a party last made a change to the same area.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: April 17, 2018
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Saurabh Bhola, Gary Denner, Paula M. Keohan, Michael J. Loughran, John Meade
  • Patent number: 9946988
    Abstract: Techniques are disclosed for managing development of a model set comprised of one or more object models by a plurality of model developers. Each model developer may be considered an interested party. For example, when a model developer changes an area of the model, that person becomes the most interested party in other changes made to the same area. An automated mechanism is provided to track changes made to the model set and informs interested parties as changes are made or after changes are made to the model based on a weighting system. In one embodiment, the weighting system may be based on a distance from the changed portions and on the amount of time since a party last made a change to the same area.
    Type: Grant
    Filed: September 28, 2011
    Date of Patent: April 17, 2018
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Saurabh Bhola, Gary Denner, Paula M. Keohan, Michael J. Loughran, John Meade
  • Publication number: 20170293667
    Abstract: This invention relates to a system, method and computer program product for a data warehouse model validation system, said data warehouse model validation system having an ETL model and a corresponding data warehouse model, said data ETL system comprising: an element group locator for locating an element group across the ETL model and the data warehouse model, whereby the element group comprises ETL elements and related data warehouse elements; an inconsistency determiner for determining inconsistencies between the ETL elements and data warehouse elements, whereby one or more elements are missing from the data warehouse model or one or more elements in the data warehouse model do not correspond to expected elements or features of elements; and an inconsistency recorder for recording any located missing elements or unexpected elements from the located element group.
    Type: Application
    Filed: April 27, 2017
    Publication date: October 12, 2017
    Inventors: Gary Denner, Paul Kilroy, Michael J. Loughran
  • Publication number: 20170293641
    Abstract: This invention relates to a system, method and computer program product for a data warehouse model validation system, said data warehouse model validation system having an ETL model and a corresponding data warehouse model, said data ETL system comprising: an element group locator for locating an element group across the ETL model and the data warehouse model, whereby the element group comprises ETL elements and related data warehouse elements; an inconsistency determiner for determining inconsistencies between the ETL elements and data warehouse elements, whereby one or more elements are missing from the data warehouse model or one or more elements in the data warehouse model do not correspond to expected elements or features of elements; and an inconsistency recorder for recording any located missing elements or unexpected elements from the located element group.
    Type: Application
    Filed: April 6, 2016
    Publication date: October 12, 2017
    Inventors: Gary Denner, Paul Kilroy, Michael J. Loughran
  • Publication number: 20130080349
    Abstract: Techniques are disclosed for managing development of a model set comprised of one or more object models by a plurality of model developers. Each model developer may be considered an interested party. For example, when a model developer changes an area of the model, that person becomes the most interested party in other changes made to the same area. An automated mechanism is provided to track changes made to the model set and informs interested parties as changes are made or after changes are made to the model based on a weighting system. In one embodiment, the weighting system may be based on a distance from the changed portions and on the amount of time since a party last made a change to the same area.
    Type: Application
    Filed: September 28, 2011
    Publication date: March 28, 2013
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Saurabh Bhola, Gary Denner, Paula M. Keohan, Michael J. Loughran, John Meade
  • Publication number: 20130080350
    Abstract: Techniques are disclosed for managing development of a model set comprised of one or more object models by a plurality of model developers. Each model developer may be considered an interested party. For example, when a model developer changes an area of the model, that person becomes the most interested party in other changes made to the same area. An automated mechanism is provided to track changes made to the model set and informs interested parties as changes are made or after changes are made to the model based on a weighting system. In one embodiment, the weighting system may be based on a distance from the changed portions and on the amount of time since a party last made a change to the same area.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 28, 2013
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Saurabh Bhola, Gary Denner, Paula M. Keohan, Michael J. Loughran, John Meade