Patents by Inventor Michael J. Loughran
Michael J. Loughran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240076291Abstract: The present invention relates to compounds of Formula (I): and pharmaceutically acceptable salts or prodrug thereof. The present invention also relates to compositions comprising at least one compound of Formula (I), and methods of using the compounds of Formula (I) for treatment or prophylaxis of lysosomal storage diseases, neurodegenerative disease, cystic disease, cancer, or a diseases or disorders associated with elevated levels of glucosylceramide (GlcCer), glucosylsphingosine (GlcSph) and/or other glucosylceramide-based glycosphingolipids (GSLs).Type: ApplicationFiled: November 18, 2021Publication date: March 7, 2024Applicant: MERCK SHARP & DOHME LLCInventors: Michael J. Breslin, Mark E. Fraley, H. Marie Loughran, James J. Mulhearn, Anthony J. Roecker, Kathy M. Schirripa, Shawn J. Stachel
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Patent number: 10733175Abstract: This invention relates to a system, method and computer program product for a data warehouse model validation system, said data warehouse model validation system having an ETL model and a corresponding data warehouse model, said data ETL system comprising: an element group locator for locating an element group across the ETL model and the data warehouse model, whereby the element group comprises ETL elements and related data warehouse elements; an inconsistency determiner for determining inconsistencies between the ETL elements and data warehouse elements, whereby one or more elements are missing from the data warehouse model or one or more elements in the data warehouse model do not correspond to expected elements or features of elements; and an inconsistency recorder for recording any located missing elements or unexpected elements from the located element group.Type: GrantFiled: April 27, 2017Date of Patent: August 4, 2020Assignee: International Business Machines CorporationInventors: Gary Denner, Paul Kilroy, Michael J. Loughran
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Patent number: 10585875Abstract: This invention relates to a system, method and computer program product for a data warehouse model validation system, said data warehouse model validation system having an ETL model and a corresponding data warehouse model, said data ETL system comprising: an element group locator for locating an element group across the ETL model and the data warehouse model, whereby the element group comprises ETL elements and related data warehouse elements; an inconsistency determiner for determining inconsistencies between the ETL elements and data warehouse elements, whereby one or more elements are missing from the data warehouse model or one or more elements in the data warehouse model do not correspond to expected elements or features of elements; and an inconsistency recorder for recording any located missing elements or unexpected elements from the located element group.Type: GrantFiled: April 6, 2016Date of Patent: March 10, 2020Assignee: International Businses Machines CorporationInventors: Gary Denner, Paul Kilroy, Michael J. Loughran
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Patent number: 9946989Abstract: Techniques are disclosed for managing development of a model set comprised of one or more object models by a plurality of model developers. Each model developer may be considered an interested party. For example, when a model developer changes an area of the model, that person becomes the most interested party in other changes made to the same area. An automated mechanism is provided to track changes made to the model set and informs interested parties as changes are made or after changes are made to the model based on a weighting system. In one embodiment, the weighting system may be based on a distance from the changed portions and on the amount of time since a party last made a change to the same area.Type: GrantFiled: September 14, 2012Date of Patent: April 17, 2018Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Saurabh Bhola, Gary Denner, Paula M. Keohan, Michael J. Loughran, John Meade
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Patent number: 9946988Abstract: Techniques are disclosed for managing development of a model set comprised of one or more object models by a plurality of model developers. Each model developer may be considered an interested party. For example, when a model developer changes an area of the model, that person becomes the most interested party in other changes made to the same area. An automated mechanism is provided to track changes made to the model set and informs interested parties as changes are made or after changes are made to the model based on a weighting system. In one embodiment, the weighting system may be based on a distance from the changed portions and on the amount of time since a party last made a change to the same area.Type: GrantFiled: September 28, 2011Date of Patent: April 17, 2018Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Saurabh Bhola, Gary Denner, Paula M. Keohan, Michael J. Loughran, John Meade
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Publication number: 20170293667Abstract: This invention relates to a system, method and computer program product for a data warehouse model validation system, said data warehouse model validation system having an ETL model and a corresponding data warehouse model, said data ETL system comprising: an element group locator for locating an element group across the ETL model and the data warehouse model, whereby the element group comprises ETL elements and related data warehouse elements; an inconsistency determiner for determining inconsistencies between the ETL elements and data warehouse elements, whereby one or more elements are missing from the data warehouse model or one or more elements in the data warehouse model do not correspond to expected elements or features of elements; and an inconsistency recorder for recording any located missing elements or unexpected elements from the located element group.Type: ApplicationFiled: April 27, 2017Publication date: October 12, 2017Inventors: Gary Denner, Paul Kilroy, Michael J. Loughran
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Publication number: 20170293641Abstract: This invention relates to a system, method and computer program product for a data warehouse model validation system, said data warehouse model validation system having an ETL model and a corresponding data warehouse model, said data ETL system comprising: an element group locator for locating an element group across the ETL model and the data warehouse model, whereby the element group comprises ETL elements and related data warehouse elements; an inconsistency determiner for determining inconsistencies between the ETL elements and data warehouse elements, whereby one or more elements are missing from the data warehouse model or one or more elements in the data warehouse model do not correspond to expected elements or features of elements; and an inconsistency recorder for recording any located missing elements or unexpected elements from the located element group.Type: ApplicationFiled: April 6, 2016Publication date: October 12, 2017Inventors: Gary Denner, Paul Kilroy, Michael J. Loughran
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Publication number: 20130080349Abstract: Techniques are disclosed for managing development of a model set comprised of one or more object models by a plurality of model developers. Each model developer may be considered an interested party. For example, when a model developer changes an area of the model, that person becomes the most interested party in other changes made to the same area. An automated mechanism is provided to track changes made to the model set and informs interested parties as changes are made or after changes are made to the model based on a weighting system. In one embodiment, the weighting system may be based on a distance from the changed portions and on the amount of time since a party last made a change to the same area.Type: ApplicationFiled: September 28, 2011Publication date: March 28, 2013Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Saurabh Bhola, Gary Denner, Paula M. Keohan, Michael J. Loughran, John Meade
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Publication number: 20130080350Abstract: Techniques are disclosed for managing development of a model set comprised of one or more object models by a plurality of model developers. Each model developer may be considered an interested party. For example, when a model developer changes an area of the model, that person becomes the most interested party in other changes made to the same area. An automated mechanism is provided to track changes made to the model set and informs interested parties as changes are made or after changes are made to the model based on a weighting system. In one embodiment, the weighting system may be based on a distance from the changed portions and on the amount of time since a party last made a change to the same area.Type: ApplicationFiled: September 14, 2012Publication date: March 28, 2013Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Saurabh Bhola, Gary Denner, Paula M. Keohan, Michael J. Loughran, John Meade