Patents by Inventor Michael J. McCluskie

Michael J. McCluskie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugates for the Prevention or Treatment of Nicotine Addiction
    Publication number: 20150157708
    Abstract: The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment and/or prevention of nicotine addiction.
    Type: Application
    Filed: February 5, 2015
    Publication date: June 11, 2015
    Inventors: Alan Daniel Brown, Heather Lynn Davis, David P. Gervais, Lyn Howard Jones, James R. Merson, David Cameron Pryde, David R. Stead, Michael J. McCluskie, Jennifer Marie Thorn, Paul Robert Mehelic, Parag Ashok Kolhe, Keshab Bhattacharya, Jari Ilmari Finneman, Erin Kristen Parsons, Nickolas Anastasiou
  • Conjugates for the prevention or treatment of nicotine addiction
    Patent number: 8980276
    Abstract: The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment and/or prevention of nicotine addiction.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: March 17, 2015
    Assignee: Pfizer Inc
    Inventors: Alan Daniel Brown, Heather Lynn Davis, David P. Gervais, Lyn Howard Jones, James R. Merson, David Cameron Pryde, David R. Stead, Michael J. McCluskie, Jennifer Marie Thorn, Paul Robert Mehelic, Parag Ashok Kolhe, Keshab Bhattacharya, Jari Ilmari Finneman, Erin Kristen Parsons, Nickolas Anastasiou
  • Methods and products for inducing mucosal immunity
    Patent number: 8574599
    Abstract: The invention relates methods and products for inducing mucosal immunity. In particular, the invention relates to the use of immunostimulatory oligonucleotides containing a CpG motif for inducing mucosal immunity. The CpG immunostimulatory oligonucleotides may be administered alone or in combination with antigen and/or with other adjuvants.
    Type: Grant
    Filed: May 21, 1999
    Date of Patent: November 5, 2013
    Assignee: Ottawa Hospital Research Institute
    Inventors: Michael J. McCluskie, Heather L. Davis
  • CONJUGATES FOR THE PREVENTION OR TREATMENT OF NICOTINE ADDICTION
    Publication number: 20110300174
    Abstract: The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment and/or prevention of nicotine addiction.
    Type: Application
    Filed: June 2, 2011
    Publication date: December 8, 2011
    Applicant: Pfizer Vaccines LLC
    Inventors: Alan Daniel BROWN, Heather Lynn DAVIS, David P. GERVAIS, Lyn Howard JONES, James R. MERSON, David Cameron PRYDE, David R. STEAD, Michael J. MCCLUSKIE, Jennifer Marie THORN, Paul Robert MEHELIC, Parag Ashok KOLHE, Keshab BHATTACHARYA, Jari Ilmari FINNEMAN, Erin Kristen PARSONS, Nickolas ANASTASIOU
  • IMMUNOSTIMULATORY NUCLEIC ACID OIL-IN-WATER FORMULATIONS AND RELATED METHODS OF USE
    Publication number: 20090155307
    Abstract: The invention involves methods and compositions of an immunostimulatory nucleic acid in oil-in-water emulsions for topical delivery. The compositions can be used to stimulate immune responses, particularly useful in the prevention and/or treatment of infectious disease and cancer.
    Type: Application
    Filed: August 21, 2008
    Publication date: June 18, 2009
    Applicant: Coley Pharmaceutical Group, Ltd.
    Inventors: Heather L. Davis, Michael J. McCluskie
  • Methods and compositions for inducing innate immune responses
    Publication number: 20090017021
    Abstract: The invention relates to TLR ligand formulations that comprise immune stimulating complexes and their use in inducing innate immunity.
    Type: Application
    Filed: April 17, 2008
    Publication date: January 15, 2009
    Applicants: Coley Pharmaceutical Group, Ltd., CSL Limited
    Inventors: Heather L. Davis, Michael J. McCluskie, Debra P. Drane
  • Methods and products for inducing mucosal immunity
    Publication number: 20040266719
    Abstract: The invention relates methods and products for inducing mucosal immunity. In particular, the invention relates to the use of immunostimulatory oligonucleotides containing a CpG motif for inducing mucosal immunity. The CpG immunostimulatory oligonucleotides may be administered alone or in combination with antigen and/or with other adjuvants.
    Type: Application
    Filed: July 9, 2004
    Publication date: December 30, 2004
    Inventors: Michael J. McCluskie, Heather L. Davis
  • Immunostimulatory nucleic acid oil-in-water formulations and related methods of use
    Publication number: 20040235770
    Abstract: The invention involves methods and compositions of an immunostimulatory nucleic acid in oil-in-water emulsions for topical delivery. The compositions can be used to stimulate immune responses, particularly useful in the prevention and/or treatment of infectious disease and cancer.
    Type: Application
    Filed: April 1, 2004
    Publication date: November 25, 2004
    Applicant: Coley Pharmaceutical Group, Ltd.
    Inventors: Heather L. Davis, Michael J. McCluskie
  • Immunostimulatory nucleic acids for inducing a Th2 immune response
    Publication number: 20010044416
    Abstract: The invention relates to methods and products for inducing an immune response using immunostimulatory nucleic acids. In particular the immunostimulatory nucleic acids preferentially induce a Th2 immune response. The invention is useful for treating and preventing disorders associated with a Th1 immune response or for creating a Th2 environment for treating disorders that are sensitive to Th2 immune responses.
    Type: Application
    Filed: January 22, 2001
    Publication date: November 22, 2001
    Inventors: Michael J. McCluskie, Heather L. Davis