Abstract: Disclosed herein is a point determination and projection device configured to automatically detect the location of a point of interest, such as a midpoint or other intermediate point on a surface, and to project light or another image onto such point of interest to indicate its location to a user. In accordance with certain aspects of an embodiment of the invention, the device includes remote distance measurement devices, such as laser distance measurement devices, that measure the distance to, for example, corners of a wall surface, and a digital protractor that measures the angle between the two remote distance measurement devices. Based on those measurements, a processor calculates the location of a predesignated point of interest, such as a midpoint or other intermediate point between the two wall corners, and projects a light or other image toward the location of such midpoint or other intermediate point to indicate such location to a user.

Abstract: A display may have a pixel array such as a liquid crystal pixel array. The pixel array may be illuminated with backlight illumination from a direct-lit backlight unit. The backlight unit may include an array of light-emitting diodes (LEDs) on a printed circuit board. The display may have a notch to accommodate an input-output component. Reflective layers may be included in the notch. The backlight may include a color conversion layer with a property that varies as a function of position. The light-emitting diodes may be covered by a slab of encapsulant with recesses in an upper surface.

Abstract: The disclosure relates to barcoded polymer nanoparticles for in vivo screening and for in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticles, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, associated with polynucleotide barcodes, for therapeutic delivery, and for high throughput in vivo screening of drug delivery nanoparticles.

Abstract: A sterilization enclosure to be placed within a sterilizer, the sterilization enclosure defining an interior for accommodating at least one surgical instrument and maintaining sterility of the at least one surgical instrument after the sterilization enclosure is removed from the sterilizer. The enclosure comprising a light source and a transparent window. The light source to illuminate the interior and the transparent window positioned such that the interior and the at least one surgical instrument are visible through the transparent window. A process indicator that is either disposed within the interior or coupled to an external surface of the sterilization enclosure. The process indicator in fluid communication with the interior of the sterilization enclosure such that the process indicator is exposed to a sterilant agent disposed within the interior of the sterilization enclosure to measure a characteristic within the interior during a sterilization process.

Abstract: Presented are a method and apparatus for surgical procedures. An exemplary apparatus includes a body having a longitudinal axis, the body comprising a hollow passageway extending through the longitudinal axis from an inlet at a distal end to a port at a proximal end. The apparatus further includes an electrode extending from the distal end of the body adjacent to the inlet. The apparatus also includes a swivel portion moveably coupled to the port, the swivel portion having a second hollow passageway fluidly coupled to the hollow conduit extending from the port to an outlet, wherein the swivel portion comprises a first swivel element operable to rotate around the longitudinal axis relative to the body, and wherein the swivel portion comprises a second swivel element operable to rotate relative to the first swivel element and the body.

Abstract: A redox flow battery (RFB) system with a low-cost online turbidity sensor to detect the early stages of electrolyte precipitate formation is described. The inline turbidity sensor can be used in either absorption or scattering mode. The RFB system may optionally include an RGB color sensor to monitor the charge-discharge cycles by detecting color change in the electrolyte.

Abstract: Provided herein are energy storage devices. In some cases, the energy storage devices are capable of being transported on a vehicle and storing a large amount of energy. An energy storage device is provided comprising at least one liquid metal electrode, an energy storage capacity of at least about 1 MWh and a response time less than or equal to about 100 milliseconds (ms).

Abstract: Various methods and systems are provided for a shift assembly for a vehicle transmission. In one example, a shift assembly for a transmission includes a first barrel cam including a first cam track; a second barrel cam arranged coaxially with the first barrel cam and including a second cam track; a first motor configured to drive the first barrel cam independent of the second barrel cam; and a second motor configured to drive the second barrel cam independent of the first barrel cam.

Abstract: The invention relates to barcoded nucleic acid nanostructure delivery compositions for in vivo screening for subsequent use in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to nucleic acid nanostructure delivery compositions, such as DNA origami structures, associated with barcodes for high throughput in vivo screening of the nucleic acid nanostructure delivery compositions for subsequent use in drug delivery, and methods therefor.

Abstract: A surgical stapler, or fastening instrument, may generally comprise a layer, such as a tissue thickness compensator, for example, releasably attached to a fastener cartridge and/or anvil by a flowable attachment portion. The flowable attachment portion may be indefinitely flowable. The flowable attachment portion may be flowable from the time that layer is installed to the fastener cartridge to the time in which the layer is implanted to patient tissue. The flowable attachment portion may comprise a pressure sensitive adhesive. The flowable attachment portion may comprise an adhesive laminate comprising a base layer comprising the tissue thickness compensator and an adhesive layer on at least a portion of a surface of the base layer comprising the pressure sensitive adhesive. Articles of manufacture comprising flowable attachment portion and methods of making and using the flowable attachment portion are also described.

Abstract: A boot comprising a central axis and an inner surface and an outer surface. The boot having a first fastening region the inner surface of which is adapted to seal against a first component and a second fastening region the inner surface of which is adapted to seal against a second component. The boot having an interior volume between the first fastening region and the second fastening region. The boot having an intermediate region connected at a first end to the first fastening region and connected at a second end to the second fastening region. The intermediate region having a convolution located between the first end and second end, wherein the outer surface of the convolution is convex.

Abstract: Presented are a method and apparatus for surgical procedures. An exemplary apparatus includes a body having a longitudinal axis, the body comprising a hollow passageway extending through the longitudinal axis from an inlet at a distal end to a port at a proximal end. The apparatus further includes an electrode extending from the distal end of the body adjacent to the inlet. The apparatus also includes a swivel portion moveably coupled to the port, the swivel portion having a second hollow passageway fluidly coupled to the hollow conduit extending from the port to an outlet, wherein the swivel portion comprises a first swivel element operable to rotate around the longitudinal axis relative to the body, and wherein the swivel portion comprises a second swivel element operable to rotate relative to the first swivel element and the body.

Abstract: A system may include one, two or more magnetic field systems. The magnetic field system may be configured to provide a magnetic field in a first direction to the tissue. The magnetic field system may include at least one magnetic field source to produce the magnetic field. The magnetic field produced by the at least one magnetic field source may include a magnetic field produced by at least one of a permanent magnet, a temporary magnet or electric current flow through a conductor. The same or a second magnetic field system may be configured to provide a second magnetic field in a second direction to the tissue. The magnetic field system may include two or more sources to provide the magnetic field in a second, third or fourth direction that is non-parallel to the first direction.

Abstract: A device used in conjunction with fixation hardware to provide a two-stage process to address the competing needs of immobilization and re-establishment of normal stress-strain trajectories in grafted bone. A method of determining a patient-specific stress/strain pattern that utilizes a model based on 3D CT data of the relevant structures and cross-sectional data of the three major chewing muscles. The forces on each of the chewing muscles are determined based on the model using predetermined bite forces such that a stiffness of cortical bone in the patient's mandible is determined. Based on the stiffness data, suitable implantation hardware can be designed for the patient by adjusting external topological and internal porous geometries that reduce the stiffness of biocompatible metals to thereby restore normal bite forces of the patient. A method of 3D printing nitinol to create a patient-specific device to facilitate the establishment of a normal stress-strain trajectory in grafted bone.

Abstract: Disclosed herein is a point determination and projection device configured to automatically detect the location of a point of interest, such as a midpoint or other intermediate point on a surface, and to project light or another image onto such point of interest to indicate its location to a user. In accordance with certain aspects of an embodiment of the invention, the device includes remote distance measurement devices, such as laser distance measurement devices, that measure the distance to, for example, corners of a wall surface, and a digital protractor that measures the angle between the two remote distance measurement devices. Based on those measurements, a processor calculates the location of a predesignated point of interest, such as a midpoint or other intermediate point between the two wall corners, and projects a light or other image toward the location of such midpoint or other intermediate point to indicate such location to a user.

Abstract: A device used in conjunction with fixation hardware to provide a two-stage process to address the competing needs of immobilization and re-establishment of normal stress-strain trajectories in grafted bone. A method of determining a patient-specific stress/strain pattern that utilizes a model based on 3D CT data of the relevant structures and cross-sectional data of the three major chewing muscles. The forces on each of the chewing muscles are determined based on the model using predetermined bite forces such that a stiffness of cortical bone in the patient's mandible is determined. Based on the stiffness data, suitable implantation hardware can be designed for the patient by adjusting external topological and internal porous geometries that reduce the stiffness of biocompatible metals to thereby restore normal bite forces of the patient.

Abstract: Presented is a method and apparatus for aiding medical procedures. An apparatus includes a housing defining a first opening, a second opening, and a interior, and a first cleaning element maintained within the interior relative to the first opening, the first cleaning element comprising at least one cleaning agent operable to remove extraneous debris from an object. The apparatus further includes a second cleaning element maintained with the interior relative to the second opening, the second cleaning element comprising at least one cleaning material and at least one white reference material, the at least one cleaning material operable to remove debris from an object. The apparatus also includes a conduit defining a passage from a first end of the housing to a second end of the housing.

Abstract: An electrosurgical device having an electrode with a first portion whose exterior is electrically uninsulated, a second portion whose exterior is electrically insulated, and a third portion. An elongated hollow body has an internal cavity, a front end, a rear end, an external surface. An electrical circuit is arranged within the body. The second portion of the electrode is not surrounded by the hollow body. A first button is arranged on the external surface of the body for controlling a current flow at a first level. A vacuum tube is slidably engaged by the body. A vacuum outlet port is arranged near the rear end, and the outlet port, internal cavity, and vacuum inlet are in fluid communication with each other.

Abstract: Presented are an apparatus, method and electrosurgical device for surgical procedures. An exemplary apparatus includes a body comprising a longitudinal axis and an electrical wire maintained within the body extending along the longitudinal axis, and an electrode extending from a distal end of the body operably coupled to the electrical wire, the electrode with the electrical wire operable to conduct a flow of current at a plurality of levels. The apparatus further includes a first button arranged on an external surface of the body, the first button operable for selecting the flow of current at each one of the plurality of levels through the electrical wire and the electrode, and a second button arranged on the external surface of the body adjacent the first button, the second button operable activate and deactivate the flow of current to the electrode.

Abstract: A sterilization enclosure to be placed within a sterilizer, the sterilization enclosure defining an interior for accommodating at least one surgical instrument and maintaining sterility of the at least one surgical instrument after the sterilization enclosure is removed from the sterilizer. The enclosure comprising a light source and a transparent window. The light source to illuminate the interior and the transparent window positioned such that the interior and the at least one surgical instrument are visible through the transparent window. A process indicator that is either disposed within the interior or coupled to an external surface of the sterilization enclosure. The process indicator in fluid communication with the interior of the sterilization enclosure such that the process indicator is exposed to a sterilant agent disposed within the interior of the sterilization enclosure to measure a characteristic within the interior during a sterilization process.