Abstract: A method of correcting spinal deformity, which includes locating pharmaceutical-loaded implants adjacent to targeted spinal growth plates, and then eluting the pharmaceutical onto the growth plates. Preferably, the method involves correcting spinal deformity by simply inserting a pharmaceutical-eluting pedicle screw onto the concave side of a scoliotic curve. In some embodiments, the screw has a cannulated internal reservoir that contains a growth-inhibiting pharmaceutical (such as a tetracycline) and at least one fenestration that allows the pharmaceutical to elute onto the vertebral body growth plate.

Abstract: The use of a memory metal mesh stent as a retractor in a lateral approach to the spine. The expanded stent is used as a conduit through which an implant can pass. This advance is predicated upon the appreciation that modern stent implants have diameters that are large enough to accommodate passage of an intervertebral spinal implant therethrough.

Abstract: Devices and methods for in situ drawing, filtering and seeding cells from the marrow of surrounding bone into a fusion cage without any of the challenges mentioned above. Various implants and devices with aspiration ports that enable in-situ harvesting and mixing of stem cells. These devices may include spinal fusion cages, long bone spacers, lateral grafts and joint replacement devices. Each device utilizes at least one aspiration port for harvesting of stem cell-containing marrow via aspiration from adjacent bony elements.

Abstract: The invention is generally related to an intervertebral implant for replacing an intervertebral disc of the human spine. The intervertebral implant includes a first conformable endplate, the first conformable endplate being conformable to a boney vertebral endplate under an anatomical load, a second endplate and a core between the endplates, wherein the first conformable endplate partitions the core from the boney vertebral endplate, whereby the core does not contact the boney vertebral endplate. The invention is also directed to a method of replacing an intervertebral disc.

Abstract: A system and method for manipulating intervertebral tissue in one embodiment includes a conduit, a segmented expansion media configured to pass through the conduit, and an expandable node comprising a plurality of abrading strands and operably connected to the intervertebral tissue removal system conduit so as to receive the segmented expansion media therein, the expandable node expandable from a first condition whereat the plurality of abrading strands define at least one opening having a first maximum diameter, to an expanded condition whereat the at least one opening has a second maximum diameter larger than the first maximum diameter, wherein the second maximum diameter is less than a minimum diameter of the segmented expansion media, such that insertion of the segmented expansion media through the intervertebral tissue removal system conduit and into the expandable node causes the expandable node to expand from the first condition to the expanded condition.

Abstract: Flexible shavers and curved access ports that reduce access and trajectory problems associated with conventional lateral approaches to the lower spine. These devices and methods allow for preparing a disc space in the lower spine at an angle that is parallel to the disc space. Consequently, these devices and methods allow for preparing with less endplate damage.

Abstract: A fusion cage has a first component that defines an outside surface that is configured to engage a vertebral endplate, and an interior surface. The fusion cage has a second component that defines first and second opposed surfaces. One of the first and second opposed surfaces can mate with the interior surface of the first component. The fusion cage can include vertical and lateral throughholes adapted to enhance fusion.

Abstract: Disclosed herein are devices and methods for removing tissue. In one aspect, a device for removing tissue includes a hollow elongate member having an outer wall and a lumen, a selectively deployable tissue-cutting element extending from the hollow elongate member, and an actuation member extending through the lumen and coupled to the hollow elongate member at a location that is distal to the tissue-cutting element. Movement of the actuation member can cause the tissue-cutting element to move from the insertion configuration where the tissue-cutting element is not deployed to a tissue-cutting configuration where the tissue-cutting element is deployed such that it is radially extended relative to the insertion configuration.

Abstract: Systems and methods are disclosed in which changes in the position and/or orientation of an anatomical structure or of a surgical tool can be measured quantitatively during surgery. In some embodiments, a surgical electronic module can be configured to attach to a surgical device, to continually detect changes in a position and/or orientation of the surgical device during surgery, and to communicate the changes to a user. In this way, where the surgical device is attached to a portion of a patient's anatomy and/or is used to manipulate the patient's anatomy, the surgical electronic module can detect changes in the position and/or orientation of said anatomy. In embodiments where more than one module is used during surgery, the modules can continually detect changes in their positions and/or orientations relative to one another, which correspond to changes in relative positions and/or orientations of the surgical devices to which the modules are attached.

Abstract: Systems and methods are disclosed in which changes in the position and/or orientation of an anatomical structure or of a surgical tool can be measured quantitatively during surgery. In some embodiments, a surgical electronic module can be configured to attach to a surgical device, to continually detect changes in a position and/or orientation of the surgical device during surgery, and to communicate the changes to a user. In this way, where the surgical device is attached to a portion of a patient's anatomy and/or is used to manipulate the patient's anatomy, the surgical electronic module can detect changes in the position and/or orientation of said anatomy. In embodiments where more than one module is used during surgery, the modules can continually detect changes in their positions and/or orientations relative to one another, which correspond to changes in relative positions and/or orientations of the surgical devices to which the modules are attached.

Abstract: Insertion and expansion devices for use in inserting motion discs, and associated methods of use.

Abstract: In intervertebral operative spinal procedures, using separate or pre-attached spreader blocks to control the directional growth of a distracting balloon.

Abstract: An intervertebral fusion device comprising inferior and superior fusion cage devices that provide an ability to correct spondylolisthesis via in-situ adjustment.

Abstract: A flexible auger design for low-torque transmitting drive shafts, which allows effective tissue material transport through curved, flexible tubes and channels. A hollow auger has a hollow center, so that the helical member hugs the inner wall of the tube and material is transported along the center axis and the inner wall of the tube. The hollow flexible auger allows for transportation of material from an operative location in the patient (material removal) as well as to operative location in the patient (material delivery).

Abstract: A spinal distractor for distracting opposed vertebrae in which a pair of elements are threadably connected by a screw having opposing threads, wherein actuating the screw spreads the elements apart and pushes the vertebrae apart.

Abstract: A spinal pedicle rod comprising an internally reinforced polymeric core that is at least partially encased within at least one polymeric coating. A dynamic stabilization device for bones in which flexible rods are combined with a pair of dynamic anchoring devices comprising i) a shank for anchoring into a bone or a vertebra, ii) a head connected to the shank, iii) a receiving part for the head and iv) a mobile element acting on the head.

Abstract: Surgical curettes or rakes with cutting edges conform or deflect to allow for contouring that follows the bony anatomy. The cutting tips can be pre-sterile, disposable and made from flexible materials including metals and polymers. The disposable tips ensure that a sharp cutting edge is exposed to the endplate for each procedure. The tips can also be adjusted to change the size of the cutting surface and window for retaining shaved disc material. The tips can pivot to provide for a self adjusting angle that allows the cutting edge to have full contact with the endplate at various angles like the pivot on a disposable razor blade.

Abstract: A surgical device. The surgical device may comprise a transducer configured to provide vibrations along a longitudinal axis and an end effector coupled to the transducer and extending from the transducer along the longitudinal axis. The surgical device also may comprise a lower jaw extending parallel to the end effector. The lower jaw may comprise a clamp face extending toward the longitudinal axis. Also, the lower jaw may be slidable relative to the end effector to bring the clamp face toward a distal end of the end effector.

Abstract: An optical trial implant device that can be used to determine an appropriate size for an intervertebral disc implant can be configured so that one or more portions of the device can be optically transparent or radiolucent. The device can include an imaging device that can be used to view and image the intervertebral space through the optically transparent portion(s) of the device. The device can be used to determine the extent and quality of preparation of an intervertebral space between adjacent vertebral bodies for a surgical procedure, such as a disc replacement or spinal fusion procedure. The acquired image information can be transmitted to a mobile computing device for display in real time and/or stored for future use. The information may also be used to determine parameters indicating the quality of endplate surface preparation.

Abstract: Disclosed herein are devices and methods for removing tissue. In one aspect, a device for removing tissue includes a hollow elongate member having an outer wall and a lumen, a selectively deployable tissue-cutting element extending from the hollow elongate member, and an actuation member extending through the lumen and coupled to the hollow elongate member at a location that is distal to the tissue-cutting element. Movement of the actuation member can cause the tissue-cutting element to move from the insertion configuration where the tissue-cutting element is not deployed to a tissue-cutting configuration where the tissue-cutting element is deployed such that it is radially extended relative to the insertion configuration.