Patents by Inventor Michael J. Seo
Michael J. Seo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240109802Abstract: A controller, process, and glass manufacturing apparatus can be configured to minimize defects. Embodiments can be adapted to control injection of nitrogen and/or argon and a mixture of nitrogen and hydrogen or nitrogen, hydrogen, and argon during glass float manufacturing to facilitate a pre-selected hydrogen concentration within a tin bath furnace while also minimizing glass surface defects that can be caused from tin condensation and tin bath impurity concentrations. Empirical use data can also be collected and provided to a pre-defined machine learning element of a host device to update a pre-defined control scheme of a controller for adapting the operational condition set points or other target values to account for furnace operation history and performance.Type: ApplicationFiled: June 27, 2023Publication date: April 4, 2024Applicant: Air Products and Chemicals, Inc.Inventors: Eric R. Seo, Liang He, Reed Jacob Hendershot, Michael J. Gallagher, Ranajit Ghosh
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Patent number: 9528989Abstract: The use of an imaging system, cell compartment markers, and molecular markers in methods for correlating the movement of molecules within a cell to a particular compartment are provided, including measuring and correlating molecule movement in adherent and non-adherent cells.Type: GrantFiled: March 30, 2012Date of Patent: December 27, 2016Assignee: Amnis CorporationInventors: Thaddeus C. George, David A. Basiji, Keith Frost, Brian E. Hall, William E. Ortyn, Michael J. Seo
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Patent number: 8953866Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.Type: GrantFiled: April 30, 2012Date of Patent: February 10, 2015Assignee: Amnis CorporationInventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
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Patent number: 8824770Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.Type: GrantFiled: March 13, 2013Date of Patent: September 2, 2014Assignee: Amnis CorporationInventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
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Patent number: 8571295Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.Type: GrantFiled: March 13, 2013Date of Patent: October 29, 2013Assignee: Amnis CorporationInventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
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Publication number: 20130251234Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.Type: ApplicationFiled: March 13, 2013Publication date: September 26, 2013Inventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
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Publication number: 20120328177Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.Type: ApplicationFiled: April 30, 2012Publication date: December 27, 2012Applicant: AMNIS CORPORATIONInventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
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Publication number: 20120244550Abstract: The use of an imaging system, cell compartment markers, and molecular markers in methods for correlating the movement of molecules within a cell to a particular compartment are provided, including measuring and correlating molecule movement in adherent and non-adherent cells.Type: ApplicationFiled: March 30, 2012Publication date: September 27, 2012Applicant: AMNIS CORPORATIONInventors: Thaddeus C. George, David A. Basiji, Keith Frost, Brian E. Hall, William E. Ortyn, Michael J. Seo
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Publication number: 20120100532Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.Type: ApplicationFiled: November 22, 2011Publication date: April 26, 2012Applicant: AMNIS CORPORATIONInventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
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Patent number: 8150136Abstract: The use of an imaging system, cell compartment markers, and molecular markers in methods for correlating the movement of molecules within a cell to a particular compartment are provided, including measuring and correlating molecule movement in adherent and non-adherent cells.Type: GrantFiled: March 16, 2005Date of Patent: April 3, 2012Assignee: Amnis CorporationInventors: Thaddeus C. George, David A. Basiji, Keith Frost, Brian E. Hall, William E. Ortyn, Michael J. Seo
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Patent number: 8103080Abstract: Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.Type: GrantFiled: March 16, 2005Date of Patent: January 24, 2012Assignee: Amnis CorporationInventors: Thaddeus C George, David A Basiji, Brian E Hall, William E Ortyn, Michael J Seo, Philip J Morrissey, Cathleen A Zimmerman
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Publication number: 20110280467Abstract: Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.Type: ApplicationFiled: July 26, 2011Publication date: November 17, 2011Applicant: Amnis CorporationInventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
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Publication number: 20090202130Abstract: The use of an imaging system, cell compartment markers, and molecular markers in methods for correlating the movement of molecules within a cell to a particular compartment are provided, including measuring and correlating molecule movement in adherent and non-adherent cells.Type: ApplicationFiled: March 16, 2005Publication date: August 13, 2009Applicant: AMNIS CORPORATIONInventors: Thaddeus C. George, David A. Basiji, Keith Frost, Brian E. Hall, William E. Ortyn, Michael J. Seo
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Publication number: 20080240539Abstract: Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.Type: ApplicationFiled: March 16, 2005Publication date: October 2, 2008Applicant: Amins CorporationInventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
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Patent number: 7087877Abstract: A pair of optical gratings are used to modulate light from an object, and the modulated light from either grating is used to determine the velocity of the object. Each optical grating is offset from a reference focal point by the same distance, one grating being offset in a positive direction, the other in a negative direction. Signals produced in response to the modulated light can be processed to determine a direction in which a primary collection lens should be moved in order to improve a focus of the imaging system on the object. The lens is moved incrementally in the direction so determined, and the process is repeated until an optimal focus is achieved. In a preferred embodiment, the signals are weighted, so that the optical grating disposed closest to the optimal focus position contributes the most to velocity detection.Type: GrantFiled: January 28, 2005Date of Patent: August 8, 2006Assignee: Amnis CorporationInventors: William E. Ortyn, Michael J. Seo, David A. Basiji, Keith L. Frost, David J. Perry
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Patent number: 6906792Abstract: When utilized in a flow imaging instrument, calibration beads provide a known data source that can be employed in various self-diagnostic, calibration and quality metric applications for the both the optical system of the flow imaging instrument, as well as the flow cell of the flow imaging instrument. Such data can be used to determine point spread functions associated with an imaging system, to determine a sensitivity of an imaging system, and to determine a focal point of the imaging system. Imagery collected from calibration beads can be used to determine core size and stability and TDI/flow speed synchronization. Calibration beads can be beneficially employed to enable stable system operation, even when very low sample concentration, or very small sample sizes are to be analyzed.Type: GrantFiled: June 10, 2004Date of Patent: June 14, 2005Assignee: Amnis CorporationInventors: William E. Ortyn, David A. Basiji, Keith L. Frost, Brian E. Hall, Michael J. Seo
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Patent number: 6875973Abstract: A pair of optical gratings are used to modulate light from an object, and the modulated light from either optical is used to determine the velocity of the object. Each optical grating is offset from a reference focal point by the same distance, one grating being offset in a positive direction, the other in a negative direction. Signals produced in response to the modulated light can be processed to determine a direction in which a primary collection lens should be moved in order to improve a focus of the imaging system on the object. The lens is moved incrementally in the direction so determined, and the process is repeated until an optimal focus is achieved. In a preferred embodiment, the signals are weighted, so that the optical grating disposed closest to the optimal focus position contributes the most to velocity detection.Type: GrantFiled: April 9, 2004Date of Patent: April 5, 2005Assignee: Amnis CorporationInventors: William E. Ortyn, Michael J. Seo, David A. Basiji, Keith L. Frost, David J. Perry
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Publication number: 20040223135Abstract: When utilized in a flow imaging instrument, calibration beads provide a known data source that can be employed in various self-diagnostic, calibration and quality metric applications for the both the optical system of the flow imaging instrument, as well as the flow cell of the flow imaging instrument. Such data can be used to determine point spread functions associated with an imaging system, to determine a sensitivity of an imaging system, and to determine a focal point of the imaging system. Imagery collected from calibration beads can be used to determine core size and stability and TDI/flow speed synchronization. Calibration beads can be beneficially employed to enable stable system operation, even when very low sample concentration, or very small sample sizes are to be analyzed.Type: ApplicationFiled: June 10, 2004Publication date: November 11, 2004Applicant: Amnis CorporationInventors: William E. Ortyn, David A. Basiji, Keith L. Frost, Brian E. Hall, Michael J. Seo
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Publication number: 20040217256Abstract: A pair of optical gratings are used to modulate light from an object, and the modulated light from either optical is used to determine the velocity of the object. Each optical grating is offset from a reference focal point by the same distance, one grating being offset in a positive direction, the other in a negative direction. Signals produced in response to the modulated light can be processed to determine a direction in which a primary collection lens should be moved in order to improve a focus of the imaging system on the object. The lens is moved incrementally in the direction so determined, and the process is repeated until an optimal focus is achieved. In a preferred embodiment, the signals are weighted, so that the optical grating disposed closest to the optimal focus position contributes the most to velocity detection.Type: ApplicationFiled: April 9, 2004Publication date: November 4, 2004Applicant: Amnis CorporationInventors: William E. Ortyn, Michael J. Seo, David A. Basiji, Keith L. Frost, David J. Perry
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Patent number: 6778263Abstract: When utilized in a flow imaging instrument, calibration beads provide a known data source that can be employed in various self-diagnostic, calibration and quality metric applications for the both the optical system of the flow imaging instrument, as well as the flow cell of the flow imaging instrument. Such data can be used to determine point spread functions associated with an imaging system, to determine a sensitivity of an imaging system, and to determine a focal point of the imaging system. Imagery collected from calibration beads can be used to determine core size and stability and TDI/flow speed synchronization. Calibration beads can be beneficially employed to enable stable system operation, even when very low sample concentration, or very small sample sizes are to be analyzed.Type: GrantFiled: January 16, 2003Date of Patent: August 17, 2004Assignee: Amnis CorporationInventors: William E. Ortyn, David A. Basiji, Keith L. Frost, Brian E. Hall, Michael J. Seo