Patents by Inventor Michael J. Siciliano

Michael J. Siciliano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Markers for detection of chromosome 16 rearrangements
    Patent number: 5869611
    Abstract: The breakpoints of the pericentric inversion of chromosome 16 have been cloned. Two genes, one at each breakpoint, have also been identified, as well as several forms of the inversion 16 fusion gene. Diagnostic applications for chromosome 16 abnormalities and, particularly acute myeloid leukemia are also within the scope of the present invention.
    Type: Grant
    Filed: November 1, 1996
    Date of Patent: February 9, 1999
    Assignees: The Regents Of The University Of Michigan and The Board of Regents, University of Texas System
    Inventors: Pu Liu, Francis S. Collins, Michael J. Siciliano, David Claxton
  • Markers for detection of chromosome 16 rearrangements
    Patent number: 5837457
    Abstract: The breakpoints of the pericentric inversion of chromosome 16 have been cloned. Two genes, one at each breakpoint, have also been identified, as well as several forms of the inversion 16 fusion gene. Diagnostic applications for chromosome 16 abnormalities and, particularly acute myeloid leukemia are also within the scope of the present invention.
    Type: Grant
    Filed: September 25, 1995
    Date of Patent: November 17, 1998
    Assignees: The Regents of the University of Michgan, The Board of Regents University of Texas System
    Inventors: Pu Liu, Francis S. Collins, Michael J. Siciliano, David Claxton
  • In-situ hybridization probes for identification and banding of specific human chromosomes and regions
    Patent number: 5538869
    Abstract: The invention relates to novel primer sets useful in preparing DNA probes specific for any chromosome or part of a chromosome, particularly human chromosomes. The DNA probes so produced may be used to paint individual chromosomes or portions of chromosomes in metephase cell spreads and in interphase nuclei. When used to paint chromosomes in metephase spreads, R-bands are readily detectable. The method is sensitive and has been shown to paint R-bands on chromosomes pieces having as few as several hundred kilobases.
    Type: Grant
    Filed: June 1, 1993
    Date of Patent: July 23, 1996
    Assignee: Board of Regents, The University of Texas System
    Inventors: Michael J. Siciliano, Pu Liu