Patents by Inventor Michael J. Singer

Michael J. Singer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Geo-boundary triggered messaging and schedule system and method of use
    Patent number: 8170580
    Abstract: A location based system is provided is configured to provide messages to a recipient based on time and location based information. The a method includes detecting when a mobile user has crossed within a predefined geo-boundary. The method further includes sending a message to the mobile user when the mobile user has crossed within the predefined geo-boundary during a predetermined time period set by an originator of the message.
    Type: Grant
    Filed: November 4, 2008
    Date of Patent: May 1, 2012
    Assignee: International Business Machines Corporation
    Inventors: John R. Dingler, Pramodh D. Narayan, Sri Ramanathan, Michael J. Singer, Matthew A. Terry, Matthew B. Trevathan
  • Systems and methods for predicting oligonucleotide melting temperature (TS)
    Patent number: 7715989
    Abstract: Software systems and methods for predicting the melting temperature (Tm) and other characteristics of oligonucleotides, including modified oligonucleotides. Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.
    Type: Grant
    Filed: June 18, 2002
    Date of Patent: May 11, 2010
    Assignee: Elitech Holding B.V.
    Inventors: Robert O. Dempcy, Alexander A. Gall, Sergey G. Lokhov, Irina A. Afonina, Michael J. Singer, Karen M. Singer, legal representative, Igor V. Kutyavin, Nicolaas M. J. Vermeulen
  • GEO-BOUNDARY TRIGGERED MESSAGING AND SCHEDULE SYSTEM AND METHOD OF USE
    Publication number: 20100113066
    Abstract: A location based system is provided is configured to provide messages to a recipient based on time and location based information. The a method includes detecting when a mobile user has crossed within a predefined geo-boundary. The method further includes sending a message to the mobile user when the mobile user has crossed within the predefined geo-boundary during a predetermined time period set by an originator of the message.
    Type: Application
    Filed: November 4, 2008
    Publication date: May 6, 2010
    Applicant: International Business Machines Corporation
    Inventors: John R. DINGLER, Pramodh D. Narayan, Sri Ramanathan, Michael J. Singer, Matthew A. Terry, Matthew B. Trevathan
  • Tleveling compositions
    Patent number: 7368549
    Abstract: Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.
    Type: Grant
    Filed: April 19, 2005
    Date of Patent: May 6, 2008
    Assignee: Epoch Biosciences, Inc.
    Inventors: Robert O. Dempcy, Alexander A Gall, Sergey G. Lokhov, Irina A. Afonina, Michael J. Singer, Igor V. Kutyavin, Nicolaas M. J. Vermeulen
  • Modified oligonucleotides for mismatch discrimination
    Patent number: 7045610
    Abstract: Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: May 16, 2006
    Assignee: Epoch Biosciences, Inc.
    Inventors: Robert O. Dempcy, Alexander A. Gall, Sergey G. Lokhov, Irina A. Afonina, Michael J. Singer, Igor V. Kutyavin, Nicolaas M. J. Vermeulen
  • Modified oligonucleotides for mismatch discrimination
    Patent number: 6949367
    Abstract: Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: September 27, 2005
    Assignee: Epoch Pharmaceuticals, Inc.
    Inventors: Robert O. Dempcy, Irina A. Afonina, Michael J. Singer, Igor V. Kutyavin
  • Tm leveling methods
    Patent number: 6683173
    Abstract: Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: January 27, 2004
    Assignee: Epoch Biosciences, Inc.
    Inventors: Robert O. Dempcy, Alexander A. Gall, Sergey G. Lokhov, Irina A. Afonina, Michael J. Singer, Igor V. Kutyavin, Nicolaas M. J. Vermeulen
  • Systems and methods for predicting oligonucleotide melting temperature (TmS)
    Publication number: 20030235822
    Abstract: Software systems and methods for predicting the melting temperature (Tm) and other characteristics of oligonucleotides, including modified oligonucleotides. Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.
    Type: Application
    Filed: June 18, 2002
    Publication date: December 25, 2003
    Applicant: Epoch Biosciences, Inc.
    Inventors: Sergey G. Lokhov, Igor V. Kutyavin, Robert O. Dempcy, Alexander A. Gall, Irina A. Afonina, Michael J. Singer, Nicolaas M.J. Vermeulen
  • TMLEVELING METHODS
    Publication number: 20030224359
    Abstract: Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.
    Type: Application
    Filed: December 21, 2001
    Publication date: December 4, 2003
    Applicant: Epoch Biosciences, Inc.
    Inventors: Robert O. Dempcy, Alexander A. Gall, Sergey G. Lokhov, Irina A. Afonina, Michael J. Singer, Igor V. Kutyavin, Nicolaas M.J. Vermeulen
  • Heat-dissipating aluminum silicon carbide composite manufacturing method
    Patent number: 6250127
    Abstract: A process for low cost manufacturing light-weight, heat-dissipating structures such as heatsinks, heat spreaders, and covers or lids for microelectronic components such as flip-chip integrated circuits from difficult-to-machine metal matrix composites such as aluminum silicon carbide (generically referred to as “Al—SiC” or “AlSiC”). The process involves selecting a mass produced quantity of Al—SiC material, forming that material into a thin ribbon, then stamping/coining the ribbon into the structures. The ribbon can be formed by extruding a thin strip from a billet of the Al—SiC material, then plurally rolling it. In this way, commonly available AlSiC composites manufactured in high volume for use in other applications such as cast automotive parts may be used.
    Type: Grant
    Filed: October 11, 1999
    Date of Patent: June 26, 2001
    Assignee: Polese Company, Inc.
    Inventors: Frank J. Polese, Jack A. Rubin, Michael J. Singer, Walter V. Chichra, Anthony P. Grodio, Vlad Ocher, Henry Escalante, William Dixon, David L. Rose, Stuart Weinshanker