Abstract: Cutting instruments and related methods are disclosed herein in which the diameter of the retrograde cutting blade can be adjusted to any of a plurality of diameter settings, allowing the same instrument to be used to form holes of different diameters. The limit diameter can be preset such that, during the cutting operation, the user need not be concerned with selecting the appropriate diameter, but rather can simply deploy the cutting blade until the preset limit is reached. Cutting instruments are also disclosed in which the retrograde cutting blade is distinct from the forward drilling tip and protected within a cavity formed in the body of the instrument when not in use, as are instruments in which the user is given visual and/or tactile feedback to confirm desired positioning of the cutting blade.

Abstract: A computer system displays a first application user interface at a first location in a three-dimensional environment. While displaying the first application user interface at the first location in the three-dimensional environment, the computer system detects, at a first time, a first input corresponding to a request to close the first application user interface. In response to detecting the first input corresponding to a request to close the first application user interface: the computer system closes the first application user interface, including ceasing to display the first application user interface in the three-dimensional environment; and, in accordance with a determination that respective criteria are met, the computer system displays a home menu user interface at a respective home menu position that is determined based on the first location of the first application user interface in the three-dimensional environment.

Abstract: Devices, systems, and methods are provided for ligament repair procedures, and can be used to establish a location and trajectory for forming a bone tunnel in bone. One exemplary embodiment of a surgical guide for using in a ligament repair procedure includes a guide arm and a carriage that can be selectively locked along the guide arm to define an angle of the bone tunnel. The guide arm also defines a location of a distal end of the bone tunnel. In some embodiments the carriage is configured to have a bullet side-loaded into it, and the bullet can be used to define a location of a proximal end of the bone tunnel. The present disclosure also provides for a gage that limits the distance a drill pin that drills the bone tunnel can travel. A variety of other, devices, systems, and methods are also provided.

Abstract: Online learning of click-through rates on search result blocks from one or more federated sources may be provided. Click-through feedback for the search result blocks may be received from the one or more federated sources in response to a query. Weights may be assigned to each of the search result blocks based on the received click-through feedback. The search result blocks may then be ranked based on the assigned weights. Finally, a search results page may be generated for displaying the ranked search results blocks to a user.

Abstract: In some aspects, an auxetic structure includes a first sheet and a second sheet, the first sheet defining therein a plurality of first openings in a first pattern, the plurality of first openings providing a first porosity and the second sheet defining therein a plurality of second openings in a second pattern to provide a second porosity. The second sheet is positioned to overlay the first sheet so that the plurality of second openings at least partially occlude the plurality of first openings to define a plurality of third openings in a third pattern, the plurality of third openings defining a third porosity less than that of the first porosity or the second porosity. The second sheet is connected to the first sheet by a plurality of distinct connection elements.

Abstract: Online learning of click-through rates on search result blocks from one or more federated sources may be provided. Click-through feedback for the search result blocks may be received from the one or more federated sources in response to a query. Weights may be assigned to each of the search result blocks based on the received click-through feedback. The search result blocks may then be ranked based on the assigned weights. Finally, a search results page may be generated for displaying the ranked search results blocks to a user.

Abstract: Methods of preparing pancreatic islets that may comprise pancreatites are provided. The methods may involve subjecting a pancreas and/or pieces thereof to disruption, such as, for example, an enzyme digest, and seeding the recovered cellular product comprising islets in a culture medium comprising at least a detectable amount of endocrine tissue and/or exocrine tissue.

Abstract: Online learning of click-through rates on search result blocks from one or more federated sources may be provided. Click-through feedback for the search result blocks may be received from the one or more federated sources in response to a query. Weights may be assigned to each of the search result blocks based on the received click-through feedback. The search result blocks may then be ranked based on the assigned weights. Finally, a search results page may be generated for displaying the ranked search results blocks to a user.

Abstract: Auxetic structures, effusion-cooling auxetic sheets, systems and devices with auxetic structures, and methods of using and methods of making auxetic structures are disclosed. An auxetic structure is disclosed which includes an elastically rigid body with opposing top and bottom surfaces. First and second pluralities of elongated apertures extend through the elastically rigid body from the top surface to the bottom surface. The first plurality of elongated apertures extends transversely with respect to the second plurality of elongated apertures. The first and/or second pluralities of elongated apertures have distorted shapes projected through the elastically rigid body at an oblique angle. The elongated apertures are cooperatively configured to provide a desired stress performance while exhibiting negative Poisson's Ratio (NPR) behavior under macroscopic planar loading conditions.

Abstract: Methods of isolating cellular products, such as pancreatic islets, may be used in diabetes research and therapeutic transplantation. The methods may involve providing a donor tissue having desired cells and undesired cells, perfusing the donor tissue with a perfusion solution, developing edema during perfusion of the donor tissue to form a swelled tissue, and separating the desired cells from undesired cellular material to obtain a cellular product. The methods may also include disrupting the tissue, and separating the desired cells from undesired cellular material to obtain the cellular product. The methods may result in an increased yield of cellular product that retains sufficient functional integrity to be useful as a transplantation resource.

Abstract: Systems and methods of manufacturing printed circuit boards using blind and internal micro vias to couple subassemblies. An embodiment of the invention provides a method of manufacturing a printed circuit including attaching a plurality of metal layer carriers to form a first subassembly including at least one copper foil pad on a first surface, applying an encapsulation material onto the first surface of the first subassembly, curing the encapsulation material and the first subassembly; applying a lamination adhesive to a surface of the cured encapsulation material, forming at least one via in the lamination adhesive and the cured encapsulation material to expose the at least one copper foil pad, attaching a plurality of metal layer carriers to form a second subassembly, and attaching the first subassembly and the second subassembly.

Abstract: Merging search results is required, for example, where an information retrieval system issues a query to multiple sources and obtains multiple results lists. In an embodiment a search engine at an Enterprise domain sends a query to the Enterprise search engine and also to a public Internet search engine. In embodiments, results lists obtained from different sources are merged using a merging model which is learnt using a machine learning process and updates when click-through data is observed for example. In examples, user information available in the Enterprise domain is used to influence the merging process to improve the relevance of results. In some examples, the user information is used for query modification. In an embodiment a user is able to impersonate a user of a specified group in order to promote particular results.

Abstract: A method of manufacturing at least a portion of a printed circuit board. The method includes: applying a lamination adhesive on a first plural-layer substrate that includes a plurality of circuit layers with at least one first metal pad on a first side of the first plural-layer substrate; applying a protective film on the lamination adhesive; forming at least one via into the lamination adhesive to expose the at least one metal pad on the first side of the first plural-layer substrate; filling at least one conductive paste into the at least one via formed in the lamination adhesive; removing the protective film to expose the lamination adhesive on the first plural-layer substrate; and attaching the first plural-layer substrate with a second plural-layer substrate that includes a plurality of circuit layers with at least one second metal pad on a second side of the second plural-layer substrate.

Abstract: A method of manufacturing at least a portion of a printed circuit board. The method includes: applying a lamination adhesive on a first plural-layer substrate that includes a plurality of circuit layers with at least one first metal pad on a first side of the first plural-layer substrate; applying a protective film on the lamination adhesive; forming at least one via into the lamination adhesive to expose the at least one metal pad on the first side of the first plural-layer substrate; filling at least one conductive paste into the at least one via formed in the lamination adhesive; removing the protective film to expose the lamination adhesive on the first plural-layer substrate; and attaching the first plural-layer substrate with a second plural-layer substrate that includes a plurality of circuit layers with at least one second metal pad on a second side of the second plural-layer substrate.

Abstract: A method of manufacturing at least a portion of a printed circuit board. The method includes: applying a lamination adhesive on a first plural-layer substrate that includes a plurality of circuit layers with at least one first metal pad on a first side of the first plural-layer substrate; applying a protective film on the lamination adhesive; forming at least one via into the lamination adhesive to expose the at least one metal pad on the first side of the first plural-layer substrate; filling at least one conductive paste into the at least one via formed in the lamination adhesive; removing the protective film to expose the lamination adhesive on the first plural-layer substrate; and attaching the first plural-layer substrate with a second plural-layer substrate that includes a plurality of circuit layers with at least one second metal pad on a second side of the second plural-layer substrate.

Abstract: Methods of manufacturing printed circuit boards using parallel processes to interconnect with subassemblies are provided. In one embodiment, the invention relates to a method of manufacturing a printed circuit board including providing a core subassembly including at least one metal layer, providing a plurality of one-metal layer carriers after parallel processing each of the plurality of one-metal layer carriers, and attaching at least two of the plurality of one-metal layer carriers with each other and with the core subassembly.

Abstract: Content insertion elements to combine search results, for example, enable a user to search the internet and obtain relevant intranet search results integrated into the results page from the internet source. In embodiments enterprise search results, desktop search results, or paid for search results are combined with internet search results. For example, a public internet search engine maintains mapping data indicating which users or user computers are authorized to access content from a second source. In an embodiment, an internet search engine receives a query from a web browser and returns results together with a content insertion element only if mapping data requirements are met. A content insertion element may hold an address of a second content source, a query and optional parameters. A web browser is able to render a web page displaying results from more than one content source using the content insertion element.

Abstract: Event prediction using hierarchical event features is described. In an embodiment a search engine monitors search results presented to users and whether users click on those search results. For example, features describing the search result events are universal resource locator prefix levels which are inherently hierarchically related. In an embodiment a graphical data structure is created and stored and used to represent the hierarchical relationships between features. An online training process is used in examples which enables knowledge to be propagated through the graphical data structure according to the hierarchical relations between features. In an example, the graphical data structure is used to predict whether a user will click on a search result and those predictions are used by the search engine to rank search results for future searches. In another example the events are advertisement impressions and the predictions are used by an online advertisement system.

Abstract: Online learning of click-through rates on search result blocks from one or more federated sources may be provided. Click-through feedback for the search result blocks may be received from the one or more federated sources in response to a query. Weights may be assigned to each of the search result blocks based on the received click-through feedback. The search result blocks may then be ranked based on the assigned weights. Finally, a search results page may be generated for displaying the ranked search results blocks to a user.

Abstract: Systems and methods of manufacturing printed circuit boards using blind and internal micro vias to couple subassemblies. An embodiment of the invention provides a method of manufacturing a printed circuit including attaching a plurality of metal layer carriers to form a first subassembly including at least one copper foil pad on a first surface, applying an encapsulation material onto the first surface of the first subassembly, curing the encapsulation material and the first subassembly; applying a lamination adhesive to a surface of the cured encapsulation material, forming at least one via in the lamination adhesive and the cured encapsulation material to expose the at least one copper foil pad, attaching a plurality of metal layer carriers to form a second subassembly, and attaching the first subassembly and the second subassembly.