Patents by Inventor Michael J. Wannemuehler

Michael J. Wannemuehler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8173104
    Abstract: Single-dose controlled-release immunogenic formulations, such as vaccines, based on bioerodible polyanhydride copolymer or homopolymer microparticles for the control of immune response mechanisms are provided. The copolymer or homopolymer microparticles degrade by surface-erosion from in vivo hydrolysis of anhydride linkages at the surface of the microparticle, which results in controlled release of immunogen(s) to a patient.
    Type: Grant
    Filed: September 4, 2009
    Date of Patent: May 8, 2012
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Matthew J. Kipper, Balaji Narasimhan, Jennifer H. Wilson, Michael J. Wannemuehler
  • Patent number: 7858093
    Abstract: Single-dose controlled-release immunogenic formulations, such as vaccines, based on bioerodible polyanhydride copolymer or homopolymer microparticles for the control of immune response mechanisms are provided. The copolymer or homopolymer microparticles degrade by surface-erosion from in vivo hydrolysis of anhydride linkages at the surface of the microparticle, which results in controlled release of immunogen(s) to a patient.
    Type: Grant
    Filed: October 28, 2005
    Date of Patent: December 28, 2010
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Matthew J. Kipper, Balaji Narasimhan, Jennifer H. Wilson, Michael J. Wannemuehler
  • Publication number: 20100021546
    Abstract: Single-dose controlled-release immunogenic formulations, such as vaccines, based on bioerodible polyanhydride copolymer or homopolymer microparticles for the control of immune response mechanisms are provided. The copolymer or homopolymer microparticles degrade by surface-erosion from in vivo hydrolysis of anhydride linkages at the surface of the microparticle, which results in controlled release of immunogen(s) to a patient.
    Type: Application
    Filed: September 4, 2009
    Publication date: January 28, 2010
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Matthew J. Kipper, Balaji Narasimhan, Jennifer H. Wilson, Michael J. Wannemuehler
  • Patent number: 5236708
    Abstract: The effectiveness of parenteral vaccination of swine with Treponema hyodysenteriae preparations is increased by reducing the protein content of the Treponema hyodysenteriae cells and subcellular components in the vaccine.
    Type: Grant
    Filed: November 3, 1989
    Date of Patent: August 17, 1993
    Assignees: Iowa State University Research Foundation, Inc., Ambico, Inc.
    Inventors: Anthony G. Ostle, Michael J. Wannemuehler