Patents by Inventor Michael J. Wolkowicz

Michael J. Wolkowicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Identifying Sperm for Forensic Applications
    Publication number: 20080318250
    Abstract: Methods and compositions for identifying and isolating sperm cells from samples containing multiple cell types are described. The methods and compositions employ antibodies that specifically bind to sperm-specific antigens located on or internal to the sperm plasma membrane. A reporter molecule may be conjugated to the antibodies to aid in the detection of sperm. The antibodies may be targeted to sperm-specific antigens in the head and/or tail of sperm to facilitate the identification and isolation of sperm cells from forensic samples prepared from sexual assault evidence. Purified DNA from the isolated sperm cells can be amplified by polymerase chain reaction to assist forensic analysis in sexual assault cases.
    Type: Application
    Filed: February 7, 2005
    Publication date: December 25, 2008
    Inventors: Linda Gilmer, Arabinda Mandal, Michael J. Wolkowicz, Kenneth L. Klotz, John C. Herr
  • Sperm specific proteins
    Patent number: 7230073
    Abstract: The present invention relates to sperm specific surface proteins, nucleic acid sequences encoding those proteins and antibodies raised against those proteins. Compositions comprising the sperm specific proteins or inhibitors of said proteins can be used in contraceptive applications.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: June 12, 2007
    Assignee: University of Virginia Patent Foundation
    Inventors: Zhonglin Hao, John C. Herr, Friederike L. Jayes, Jagathpala Shetty, Michael J. Wolkowicz
  • Human sperm specific lysozyme-like proteins
    Patent number: 7125550
    Abstract: The present invention relates to two novel, testis-specific proteins (C19 and C23) that arc lysozyme paralogues. The proteins are believed to play a role in capacitation of sperm and the fertilization of the ovum. Therefore these compounds make ideal targets for the design of contraceptive agents. The C19 and C23 proteins can also be modified to establish lysozyme activity and the modified proteins can then be used in all applications that currently exist for lysozymes.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: October 24, 2006
    Assignee: University of Virginia Patent Foundation
    Inventors: John C. Herr, Friederike Jayes, Arabinda Mandal, Jagathpala Shetty, Michael J. Wolkowicz
  • Sperm specific proteins
    Patent number: 7094547
    Abstract: The present invention relates to sperm specific surface proteins, nucleic acid sequences encoding those proteins and antibodies raised against those proteins. Compositions comprising the sperm specific proteins or inhibitors of said proteins can be used in contraceptive applications.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: August 22, 2006
    Assignee: University of Virginia Patent Foundation
    Inventors: Zhonglin Hao, John C. Herr, Friederike L. Jayes, Jagathpala Shetty, Michael J. Wolkowicz
  • Sperm specific proteins
    Patent number: 6924121
    Abstract: The present invention relates to sperm specific surface proteins, nucleic acid sequences encoding those proteins and antibodies raised against those proteins. Compositions comprising the sperm specific proteins or inhibitors of said proteins can be used in contraceptive applications.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: August 2, 2005
    Assignee: University of Virginia Patent Foundation
    Inventors: Zhonglin Hao, John C. Herr, Friederike L. Jayes, Jagathpala Shetty, Michael J. Wolkowicz
  • Sperm specific proteins
    Publication number: 20040161824
    Abstract: The present invention relates to sperm specific surface proteins, nucleic acid sequences encoding those proteins and antibodies raised against those proteins. Compositions comprising the sperm specific proteins or inhibitors of said proteins can be used in contraceptive applications.
    Type: Application
    Filed: March 25, 2004
    Publication date: August 19, 2004
    Inventors: Zhonglin Hao, John C. Herr, Friederike L. Jayes, Jagathpala Shetty, Michael J. Wolkowicz
  • Sperm specific proteins
    Publication number: 20040161825
    Abstract: The present invention relates to sperm specific surface proteins, nucleic acid sequences encoding those proteins and antibodies raised against those proteins. Compositions comprising the sperm specific proteins or inhibitors of said proteins can be used in contraceptive applications.
    Type: Application
    Filed: March 25, 2004
    Publication date: August 19, 2004
    Inventors: Zhonglin Hao, John C. Herr, Friederike L. Jayes, Jagathpala Shetty, Michael J. Wolkowicz
  • Human sperm specific lysozyme-like proteins
    Publication number: 20030129652
    Abstract: The present invention relates to two novel, testis-specific proteins (C19 and C23) that arc lysozyme paralogues. The proteins are believed to play a role in capacitation of sperm and the fertilization of the ovum. Therefore these compounds make ideal targets for the design of contraceptive agents. The C19 and C23 proteins can also be modified to establish lysozyme activity and the modified proteins can then be used in all applications that currently exist for lysozymes.
    Type: Application
    Filed: July 18, 2002
    Publication date: July 10, 2003
    Inventors: John C. Herr, Friederike Jayes, Arabinda Mandal, Jagathpala Shetty, Michael J. Wolkowicz
  • Sperm specific proteins
    Publication number: 20030087375
    Abstract: The present invention relates to sperm specific surface proteins, nucleic acid sequences encoding those proteins and antibodies raised against those proteins. Compositions comprising the sperm specific proteins or inhibitors of said proteins can be used in contraceptive applications.
    Type: Application
    Filed: July 19, 2002
    Publication date: May 8, 2003
    Inventors: Zhonglin Hao, John C. Herr, Friederike L. Jayes, Jagathpala Shetty, Michael J. Wolkowicz