Patents by Inventor Michael J. Zaworotko

Michael J. Zaworotko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11439944
    Abstract: Embodiments of the present disclosure provide for metal-organic materials (MOMs), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of separating CO2 from a gas, and the like.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: September 13, 2022
    Assignees: University of South Florida, King Abdullah University of Science and Technology
    Inventors: Mohamed Eddaoudi, Michael J. Zaworotko, Patrick Nugent, Stephen Burd, Ryan Luebke, Youssef Belmabkhout, Osama Shekhah
  • Patent number: 10857517
    Abstract: A porous chiral material of formula [M(L)1.5(A)]+X? wherein M is a metal ion; L is a nitrogen-containing bidentate ligand; A is the anion of mandelic acid or a related acid; and X? is an anion.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: December 8, 2020
    Assignees: NANKAI UNIVERSITY, UNIVERSITY OF LIMERICK
    Inventors: Shi-Yuan Zhang, Cheng-Xiong Yang, Wei Shi, Xiu-Ping Yan, Peng Cheng, Michael J. Zaworotko
  • Patent number: 10633344
    Abstract: The subject invention concerns a method for identifying complementary chemical functionalities to form a desired supramolecular synthon. The subject invention also pertains to binary phase compositions comprising one or more pharmaceutical entities and methods for producing such compositions.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: April 28, 2020
    Assignees: University of South Florida, The Regents of the University of Michigan
    Inventors: Michael J. Zaworotko, Nair Rodriguez-Hornedo, Brian Moulton
  • Publication number: 20200114297
    Abstract: Embodiments of the present disclosure provide for metal-organic materials (MOMs), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of separating CO2 from a gas, and the like.
    Type: Application
    Filed: September 26, 2019
    Publication date: April 16, 2020
    Inventors: Mohamed Eddaoudi, Michael J. Zaworotko, Patrick Nugent, Stephen Burd, Ryan Luebke, Youssef Belmabkhout, Osama Shekhah
  • Publication number: 20200009531
    Abstract: A porous chiral material of formula [M(L)1.
    Type: Application
    Filed: August 22, 2016
    Publication date: January 9, 2020
    Inventors: Wei SHI, Peng CHENG, Xiu-Ping YAN, Cheng-Xiong YANG, Michael J. ZAWOROTKO, Shi-Yuan ZHANG
  • Publication number: 20190169130
    Abstract: The subject invention concerns a method for identifying complementary chemical functionalities to form a desired supramolecular synthon. The subject invention also pertains to multiple-component phase compositions comprising one or more pharmaceutical entities and methods for producing such compositions.
    Type: Application
    Filed: February 8, 2019
    Publication date: June 6, 2019
    Inventors: Michael J. Zaworotko, Nair Rodriguez-Hornedo, Brian Moulton
  • Patent number: 10112175
    Abstract: Embodiments of the present disclosure provide for metal-organic materials (MOMs), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of separating CO2 from a gas, and the like.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: October 30, 2018
    Assignee: University of South Florida
    Inventors: Mohamed Eddaoudi, Michael J. Zaworotko, Patrick Nugent, Stephen Burd, Youssef Belmabkhout, Osama Shekhah
  • Publication number: 20170362182
    Abstract: The subject invention concerns a method for identifying complementary chemical functionalities to form a desired supramolecular synthon. The subject invention also pertains to multiple-component phase compositions comprising one or more pharmaceutical entities and methods for producing such compositions.
    Type: Application
    Filed: June 30, 2017
    Publication date: December 21, 2017
    Inventors: Michael J. Zaworotko, Nair Rodriguez-Hornedo, Brian Moulton
  • Publication number: 20170144099
    Abstract: Embodiments of the present disclosure provide for metal-organic materials (MOMs), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of separating CO2 from a gas, and the like.
    Type: Application
    Filed: February 8, 2017
    Publication date: May 25, 2017
    Applicants: University of South Florida, King Abdullah University of Science and Technology
    Inventors: Mohamed Eddaoudi, Michael J. Zaworotko, Patrick Nugent, Stephen Burd, Youssef Belmabkhout, Osama Shekhah
  • Publication number: 20170113204
    Abstract: Embodiments of the present disclosure provide for metal-organic materials (MOMs), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of separating CO2 from a gas, and the like.
    Type: Application
    Filed: February 18, 2015
    Publication date: April 27, 2017
    Inventors: Mohamed EDDAOUDI, Michael J. ZAWOROTKO, Patrick NUGENT, Stephen BURD, Ryan LUEBKE, Youssef BELMABKHOUT, Osama SHEKHAH
  • Patent number: 9604195
    Abstract: Embodiments of the present disclosure provide for metal-organic materials (MOMs), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of separating CO2 from a gas, and the like.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: March 28, 2017
    Assignees: UNIVERSITY OF SOUTH FLORIDA, KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Mohamed Eddaoudi, Michael J. Zaworotko, Patrick Nugent, Stephen Burd, Youssef Belmabkhout, Osama Shekhah
  • Patent number: 9492778
    Abstract: Embodiments of the present disclosure provide for hydrophobic multi-component metal-organic materials (MOMs) (also referred to as “hydrophobic MOM”), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of separating CO2 from a gas, and the like.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: November 15, 2016
    Assignees: University of South Florida, King Abdullah University of Science and Technology
    Inventors: Mohamed Eddaoudi, Michael J. Zaworotko, Patrick Nugent, Stephen Burd, Ryan Luebke, Youssef Belmabkhout
  • Patent number: 9138719
    Abstract: Embodiments of the present disclosure provide for hydrophobic multi-component metal-organic materials (MOMs) (also referred to as “hydrophobic MOM”), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of separating CO2 from a gas, and the like.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: September 22, 2015
    Assignee: University of South Florida
    Inventors: Mohamed Eddaoudi, Michael J. Zaworotko, Patrick Nugent, Stephen Burd, Ryan Luebke, Youssef Belmabkhout
  • Publication number: 20150158013
    Abstract: Embodiments of the present disclosure provide for metal-organic materials (MOMs), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of separating CO2 from a gas, and the like.
    Type: Application
    Filed: February 18, 2015
    Publication date: June 11, 2015
    Applicants: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY, UNIVERSITY OF SOUTH FLORIDA
    Inventors: Mohamed Eddaoudi, Michael J. Zaworotko, Patrick Nugent, Stephen Burd, Ryan Luebke, Youssef Belmabkhout, Osama Shekhah
  • Publication number: 20140162989
    Abstract: The subject invention concerns a method for identifying complementary chemical functionalities to form a desired supramolecular synthon. The subject invention also pertains to binary phase compositions comprising one or more pharmaceutical entities and methods for producing such compositions.
    Type: Application
    Filed: February 13, 2014
    Publication date: June 12, 2014
    Applicants: The Regents of the University of Michigan, University of South Florida
    Inventors: Michael J. Zaworotko, Nair Rodriguez-Hornedo, Brian Moulton
  • Patent number: 8436029
    Abstract: Crystalline salts, polymorphs, solvates, and hydrates of bicalutamide, 5-fluorouracil, donepezil, anastrozole, nelfinavir, mirtazapine, lansoprazole, and tamsulosin, or derivatives thereof are provided by the subject invention. Methods of making and using the same are also provided.
    Type: Grant
    Filed: March 17, 2005
    Date of Patent: May 7, 2013
    Assignees: Transform Pharmaceuticals, Inc., University of South Florida
    Inventors: Magali Bourghol Hickey, Matthew L. Peterson, Örn Almarsson, Michael J. Zaworotko, Tanise Shattock, Julius F. Remenar, Mark Tawa
  • Publication number: 20130023403
    Abstract: A supramolecular assembly comprising a metal-organic molecular framework and a heterocyclic macrocycle guest molecule. The metal-organic molecular framework comprises cubicuboctahedral cavities, octahemioctahedral cavities and trigonal cavities in a 1:1:2 ratio, respectively, and the heterocyclic macrocycle guest molecule is hosted by the octahemioctahedral cavity. In a preferred embodiment, the heterocyclic macrocycle guest molecule is a heme.
    Type: Application
    Filed: March 5, 2012
    Publication date: January 24, 2013
    Applicant: University of South Florida
    Inventors: Randy W. Larsen, Carissa M. Vetromile, Jason A. Perman, Lukasz Wojtas, Michael J. Zaworotko, Mohamed Eddaoudi, Yunling Liu
  • Publication number: 20120015993
    Abstract: Crystalline salts, polymorphs, solvates, and hydrates of bicalutamide, 5-fluorouracil, donepezil, anastrozole, nelfinavir, mirtazapine, lansoprazole, and tamsulosin, or derivatives thereof are provided by the subject invention. Methods of making and using the same are also provided.
    Type: Application
    Filed: March 17, 2005
    Publication date: January 19, 2012
    Applicants: University of South Florida, TRANSFORM PHARMACEUTICALS, INC.
    Inventors: Magali Bourghol Hickey, Matthew L. Peterson, Örn Almarsson, Michael J. Zaworotko, Tanise Shattock, Jennifer McMahon, Joanna Bis, Julius F. Remenar, Mark Tawa
  • Patent number: 7927613
    Abstract: A pharmaceutical composition comprising a co-crystal of an API and a co-crystal former; wherein the API has at least one functional group selected from ether, thioether, alcohol, thiol, aldehyde, ketone, thioketone, nitrate ester, phosphate ester, thiophosphate ester, ester, thioester, sulfate ester, carboxylic acid, phosphonic acid, phosphinic acid, sulfonic acid, amide, primary amine, secondary amine, ammonia, tertiary amine, sp2 amine, thiocyanate, cyanamide, oxime, nitrile diazo, organohalide, nitro, s-heterocyclic ring, thiophene, n-heterocyclic ring, pyrrole, o-heterocyclic ring, furan, epoxide, peroxide, hydroxamic acid, imidazole, pyridine and the co-crystal former has at least one functional group selected from amine, amide, pyridine, imidazole, indole, pyrrolidine, carbonyl, carboxyl, hydroxyl, phenol, sulfone, sulfonyl, mercapto and methyl thio, such that the API and co-crystal former are capable of co-crystallizing from a solution phase under crystallization conditions.
    Type: Grant
    Filed: September 11, 2003
    Date of Patent: April 19, 2011
    Assignees: University of South Florida, The Regents of the University of Michigan, Transform Pharmaceuticals, Inc.
    Inventors: Örn Almarsson, Magali Bourghol Hickey, Matthew L. Peterson, Michael J. Zaworotko, Brian Moulton, Nair Rodriguez-Hornedo
  • Publication number: 20100331285
    Abstract: A polymorph of aspirin is provided by the present invention. Methods of making and using the same are also provided.
    Type: Application
    Filed: August 23, 2010
    Publication date: December 30, 2010
    Applicants: TRANSFORM PHARMACEUTICALS, INC., UNIVERSITY OF SOUTH FLORIDA
    Inventors: Orn Almarsson, Jennifer McMahon, Vishweshwar Peddy, Matthew Peterson, Michael J. Zaworotko