Patents by Inventor Michael J. Zuscik

Michael J. Zuscik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protecting and repairing cartilage and musculoskeletal soft tissues
    Patent number: 9192653
    Abstract: Provided herein are compositions and methods related to promoting protection or repair of articular cartilage and/or musculoskeletal soft tissue by contacting the cartilage, tissues or cellular components thereof with a parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) receptor agonist or releasing factor.
    Type: Grant
    Filed: August 20, 2013
    Date of Patent: November 24, 2015
    Assignee: University of Rochester
    Inventors: Randy N. Rosier, Michael J. Zuscik, Erik Sampson, Susan V. Bukata, J. Edward Puzas, Hani Awad
  • PROTECTING AND REPAIRING CARTILAGE AND MUSCULOSKELETAL SOFT TISSUES
    Publication number: 20140066376
    Abstract: Provided herein are compositions and methods related to promoting protection or repair of articular cartilage and/or musculoskeletal soft tissue by contacting the cartilage, tissues or cellular components thereof with a parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) receptor agonist or releasing factor.
    Type: Application
    Filed: August 20, 2013
    Publication date: March 6, 2014
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Randy N. Rosier, Michael J. Zuscik, Erik Sampson, Susan V. Bukata, J. Edward Puzas, Hani Awad
  • Protecting and repairing cartilage and musculoskeletal soft tissues
    Patent number: 8513193
    Abstract: Provided herein are compositions and methods related to promoting protection or repair of articular cartilage and/or musculoskeletal soft tissue by contacting the cartilage, tissues or cellular components thereof with a parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) receptor agonist or releasing factor.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: August 20, 2013
    Assignee: University of Rochester
    Inventors: Randy N. Rosier, Michael J. Zuscik, Erik Sampson, Susan V. Bukata, J. Edward Puzas, Hani Awad
  • PROTECTING AND REPAIRING CARTILAGE AND MUSCULOSKELETAL SOFT TISSUES
    Publication number: 20120021986
    Abstract: Provided herein are compositions and methods related to promoting protection or repair of articular cartilage and/or musculoskeletal soft tissue by contacting the cartilage, tissues or cellular components thereof with a parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) receptor agonist or releasing factor.
    Type: Application
    Filed: October 13, 2009
    Publication date: January 26, 2012
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Randy N. Rosier, Michael J. Zuscik, Erik Sampson, Susan V. Bukata, J. Edward Puzas, Hani Awad
  • Model systems for neuordegenerative and cardiovascular disorders
    Publication number: 20020133832
    Abstract: New tools for determining the role the &agr;1B adrenergic receptor plays in the physiology and pathology of the brain and the cardiovascular system are provided The tools are transgenic non-human mammalian animals, particularly transgenic mice, that have integrated into the genomes of their somatic cells a transgene encoding an exogenous, wild-type &agr;1B adrenergic receptor or a variant thereof. The transgenic animals of the present invention exhibit phenotypical symptoms similar to those exhibited by individuals with neurodegenerative diseases, particularly Parkinson's disease or epilepsy. Such mammals also exhibit phenotypical symptoms similar to individuals with cardiovascular diseases such as hypertrophy of the heart and hypotension. Accordingly, these transgenic mammals are also useful for screening for drugs that ameliorate these cardiovascular conditions. Also provided is a method of determining the ability of a test agent or compound to modulate or block function of the &agr;1B adrenergic receptor.
    Type: Application
    Filed: January 18, 2002
    Publication date: September 19, 2002
    Inventors: Dianne M. Perez, Michael J. Zuscik