Patents by Inventor Michael Jaye

Michael Jaye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240156568
    Abstract: Apparatuses, systems, and methods are disclosed for a bite-safe dental care apparatus. The apparatus includes a three-dimensional body. The three-dimensional body is comprised of a substantially robust and flexible material. The apparatus includes at least one protruding member extending from the three-dimensional body. The at least one protruding member is configured to act as a bite block when inserted into a user's mouth. A width of the at least one protruding member is different than a thickness of the at least one protruding member such that the at least one protruding member props the user's mouth open at different positions when used as a bite block.
    Type: Application
    Filed: October 11, 2023
    Publication date: May 16, 2024
    Inventor: MICHAEL JAY PERRY
  • Publication number: 20170166842
    Abstract: Described are compositions and methods relating to the removal of oily stains from fabrics and other surfaces using a lipase in combination with a selected surfactant to mediate the release of fatty acids generated by the lipase. The compositions and methods have application in, e.g., laundry cleaning and dishwashing.
    Type: Application
    Filed: December 20, 2016
    Publication date: June 15, 2017
    Inventors: CHRISTIAN ADAMS, KATHERINE D. COLLIER, MICHAEL JAY PEPSIN, BRIAN SCHMIDT
  • Publication number: 20130140327
    Abstract: A colorant dispenser for use with bagged colorants includes a canister including a base and a top section. A switch is connected to the canister. A pump is adapted to be connected to the switch. The top section of the canister is configured to receive a bag containing a colorant or a cartridge for open colorants. The top section is configured to store a solvent. The pump is configured to dispense solvent or colorant depending on a position of the switch.
    Type: Application
    Filed: December 2, 2011
    Publication date: June 6, 2013
    Inventor: MICHAEL JAY MURPHY
  • Publication number: 20130059361
    Abstract: Compositions and methods for raising the level of HDL cholesterol and apolipoprotein AI in a patient and for lowering the levels of VLDL cholesterol and LDL cholesterol in a patient, including compositions and methods which effect the expression of a gene, LIPG, which encodes a lipase enzyme that is a member of the triacylglycerol lipase family or which effect the enzymatic activity of the enzyme.
    Type: Application
    Filed: December 12, 2011
    Publication date: March 7, 2013
    Inventors: Michael Jaye, Kim-Anh Thi Doan, John A. Krawiec, Kevin J. Lynch, Dilip V. Amin, Victoria J. South, Dawn Marchadier, Cyrille Maugeais, Daniel J. Rader
  • Publication number: 20110020880
    Abstract: Described are compositions and methods relating to starch processing without a phytase pretreatment step and without adjustment of the slurry pH adjustment.
    Type: Application
    Filed: April 2, 2010
    Publication date: January 27, 2011
    Inventors: SUZANNE BRENEMAN, THOMAS S. GREEN, MICHAEL JAY PEPSIN, VIVEK SHARMA, JAYARAMA K. SHETTY
  • Publication number: 20100114601
    Abstract: Systems and methods are disclosed for aiding physicians and other healthcare workers in setting prescriptions of therapeutic and/or preventive regimens. In certain embodiments the invention compares patient genotype, phenotype, proteomic, molecular, and/or other profile information with a database of information that associates third party profiles with third party responses to therapeutic and preventive regimens. The comparison information may be used by a physician or other healthcare provider to identify potential safety and/or efficacy effects of a prescribed regimen if undertaken by the patient. The systems and methods provide for the secure storage and directed access of the patient profiles.
    Type: Application
    Filed: December 29, 2009
    Publication date: May 6, 2010
    Applicant: CERNER INNOVATION, INC.
    Inventors: PENELOPE MANASCO, MICHAEL JAY WAGNER, ARTHUR L. HOLDEN, DAVID G. WANG
  • Publication number: 20090208479
    Abstract: Compositions and methods for raising the level of HDL cholesterol and apolipoprotein AI in a patient and for lowering the levels of VLDL cholesterol and LDL cholesterol in a patient, including compositions and methods which effect the expression of a gene, LIPG, which encodes a lipase enzyme that is a member of the triacylglycerol lipase family or which effect the enzymatic activity of the enzyme.
    Type: Application
    Filed: August 25, 2008
    Publication date: August 20, 2009
    Inventors: Michael Jaye, Kim-Anh Thi Doan, John A. Krawiec, Kevin J. Lynch, Dilip V. Amin, Victoria J. South, Dawn Marchadier, Cyrille Maugeais, Daniel J. Rader
  • Publication number: 20070101451
    Abstract: Lipoprotein Lipase like polypeptides, nucleic acids encoding said polypeptides, antisense sequences, and antibodies to said polypeptides are disclosed. Also disclosed are methods for the preparation of said polypeptides in a recombinant system and for the use of said polypeptides to screen for agonists and or antagonists of said polypeptides. Also disclosed are methods and compositions for the treatment of disorders of lipid metabolism.
    Type: Application
    Filed: March 7, 2006
    Publication date: May 3, 2007
    Applicant: Aventis Pharmaceuticals Products Inc.
    Inventors: Michael Jaye, Kim-Anh Doan, John Krawiec, Kevin Lynch, Dilip Amin, Victoria South
  • Publication number: 20060088504
    Abstract: Compositions and methods for raising the level of HDL cholesterol and apolipoprotein AI in a patient and for lowering the levels of VLDL cholesterol and LDL cholesterol in a patient, including compositions and methods which effect the expression of a gene, LIPG, which encodes a lipase enzyme that is a member of the triacylglycerol lipase family or which effect the enzymatic activity of the enzyme.
    Type: Application
    Filed: October 19, 2005
    Publication date: April 27, 2006
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Michael Jaye, Kim-Anh Doan, John Krawiec, Kevin Lynch, Dilip Amin, Victoria South, Dawn Marchadier, Cyrille Maugeais, Daniel Rader
  • Patent number: 7008776
    Abstract: The present invention relates to compositions for use in raising or lowering the level of LIPG polypeptide in a patient. Embodiments of the composition include compositions comprising: an anti-sense nucleic acid; a neutralizing antibody; an intracellular binding protein; an inhibitor which inhibits the enzymatic activity of LIPG polypeptide; an inhibitor which inhibits the expression of LIPG gene; a ribozyme; an LIPG polypeptide; an enhancer which increases the enzymatic activity of LIPG polypeptide; or an enhancer which increases the expression of LIPG gene. The invention relates also to methods for using the above compositions. In addition, the invention relates to a method for diagnosing a predisposition to lower cholesterol, a method for determining whether a test compound can inhibit the enzymatic reaction between LIPG polypeptide and HDL cholesterol, and methods for determining whether a test compound can enhance the enzymatic reaction between LIPG polypeptide and LDL or VLDL cholesterol.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: March 7, 2006
    Assignees: Aventis Pharmaceuticals Inc., The Trustees of the University of Pennsylvania
    Inventors: Michael Jaye, Kim-Anh Thi Doan, John A. Krawiec, Kevin J. Lynch, Dilip V. Amin, Victoria J. South, Dawn Marchadier, Cyrille Maugeais, Daniel J. Rader
  • Publication number: 20030220373
    Abstract: Use of PPAR mediators, and their pharmaceutical compositions, as ATP binding cassette transporter 1 (ABC-1) expression modulators, wherein the PPAR ligand receptor agonists of this invention are useful as inducers of ABC-1 expression.
    Type: Application
    Filed: September 9, 2002
    Publication date: November 27, 2003
    Inventors: Michael Jaye, Nicolas Duverger, George Searfoss, Anne Minnich
  • Patent number: 6635197
    Abstract: A method and apparatus for casting a molten material using a phase-change material. A funnel means is provided that includes a reservoir containing a phase-change material. The funnel means is used in conjunction with a mold. The phase-change material is heated to a temperature above its melting point. A molten material is poured into the mold, and an excess amount of the molten material is retained in the funnel means after the mold is filled. The latent heat of fusion of the phase-change material provides heat to the funnel means as the phase-change material changes from a liquid to a solid. The heat from the phase-change material maintains the temperature of the molten material within the funnel above its melting point as the molten material within the mold begins to solidify and contract, thereby permitting the excess material within the funnel means to feed into the mold and fill any voids or porosities formed by the contraction of the material within the mold.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: October 21, 2003
    Assignee: American Ordinance LLC
    Inventors: John David Cortum, Michael Jaye Mathiasmeier, Louis William Stoecker
  • Publication number: 20020195733
    Abstract: A method and apparatus for casting a molten material using a phase-change material. A funnel means is provided that includes a reservoir containing a phase-change material. The funnel means is used in conjunction with a mold. The phase-change material is heated to a temperature above its melting point. A molten material is poured into the mold, and an excess amount of the molten material is retained in the funnel means after the mold is filled. The latent heat of fusion of the phase-change material provides heat to the funnel means as the phase-change material changes from a liquid to a solid. The heat from the phase-change material maintains the temperature of the molten material within the funnel above its melting point as the molten material within the mold begins to solidify and contract, thereby permitting the excess material within the funnel means to feed into the mold and fill any voids or porosities formed by the contraction of the material within the mold.
    Type: Application
    Filed: June 25, 2001
    Publication date: December 26, 2002
    Inventors: John David Cortum, Michael Jaye Mathiasmeier, Louis William Stoecker
  • Patent number: 5849538
    Abstract: The present invention is directed to DNA encoding human endothelial cell growth factors, and to plasmids comprising said DNA. In particular, the invention relates to DNA encoding a cleavable signal peptide and an endothelial cell growth factor, wherein removal of said signal peptide yields a mature form of the growth factor.
    Type: Grant
    Filed: April 11, 1997
    Date of Patent: December 15, 1998
    Assignee: Rhone-Poulenc Rorer Pharmaceuticals Inc.
    Inventors: Michael Jaye, Wilson Burgess, Thomas Maciag, William N. Drohan
  • Patent number: 5827826
    Abstract: The present invention is directed to compositions comprising endothelial cell growth factor, an acceptable carrier and, optionally, an extracellular matrix protein, a glycosaminoglycan or serum albumin. The compositions are useful for wound repair.
    Type: Grant
    Filed: November 4, 1996
    Date of Patent: October 27, 1998
    Assignee: Rhone-Poulenc Rorer Pharmaceuticals Inc.
    Inventors: Michael Jaye, Wilson Burgess, Thomas Maciag, William N. Drohan
  • Patent number: 5571790
    Abstract: Endothelial cell growth factor is achieved through the application of recombinant DNA technology to prepare cloning vehicles encoding the ECGF protein and procedures are disclosed for recovering ECGF protein essentially free of other proteins of human origin. The product is useful for, among other purposes, diagnostic applications and as potential in the treatment of damaged blood vessels or other endothelial cell-lined structures.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 5, 1996
    Assignee: Rhone-Poulenc Rorer Pharmaceuticals, Inc.
    Inventors: Michael Jaye, Wilson Burgess, Thomas Maciag, William N. Drohan
  • Patent number: 5270452
    Abstract: Pure homogeneous glia maturation factor is disclosed with methods for producing it from neutral sources and by molecular cloning and genetic engineering.
    Type: Grant
    Filed: October 31, 1991
    Date of Patent: December 14, 1993
    Assignee: Rhone-Poulenc Rorer Pharmaceuticals Inc.
    Inventors: Ramon Lim, Ruth Kaplan, Michael Jaye
  • Patent number: 4868113
    Abstract: Endothelial cell growth factor is achieved through the application of recombinant DNA technology to prepare cloning vehicles encoding the ECGF protein and procedures are disclosed for recovering ECGF protein essentially free of other proteins of human origin. The product is useful for, among other purposes, diagnostic applications and as potential in the treatment of damaged blood vessels or other endothelial cell-line structures.
    Type: Grant
    Filed: March 3, 1986
    Date of Patent: September 19, 1989
    Assignee: Rorer Biotechnology, Inc.
    Inventors: Michael Jaye, Wilson Burgess, Thomas Maciag, William Drohan