Abstract: An integrated compressor comprises an electric motor that is prone to high temperatures. In a first cooling feature, axial and/or radial cooling channels are provided through the stator of the motor to supply coolant to portions of the stator that are prone to high temperatures. In a second cooling feature, jets are used to spray coolant towards the end-windings of the motor, to thereby cool the end-windings.

Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 216, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 216, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: A mechanism for generating denoised basis images for a computed tomography scanner. An input dataset, comprising first and second basis image data, is processed using a machine-learning algorithm process to produce the denoised basis images. The first and second basis image data each comprise at least one basis image, wherein the type of image differs between the first and second basis image data.

Abstract: A system and method for operation of an autonomous vehicle (AV) yard truck is provided. A processor facilitates autonomous movement of the AV yard truck, and connection to and disconnection from trailers. A plurality of sensors are interconnected with the processor that sense terrain/objects and assist in automatically connecting/disconnecting trailers. A server, interconnected, wirelessly with the processor, that tracks movement of the truck around and determines locations for trailer connection and disconnection. A door station unlatches/opens rear doors of the trailer when adjacent thereto, securing them in an opened position via clamps, etc. The system computes a height of the trailer, and/or if landing gear of the trailer is on the ground and interoperates with the fifth wheel to change height, and whether docking is safe, allowing a user to take manual control, and optimum charge time(s). Reversing sensors/safety, automated chocking, and intermodal container organization are also provided.

Abstract: A transfer device for unloading a transport loading aid with stacked article carriers and for loading a target loading aid with the carriers includes a base frame, loading tongues independently movable by first drives between retracted initial and extended receiving positions, clamping jaws for gripping at least one carrier relatively movable by a second drive between retracted opened and abutting clamping positions, and a lifting frame movable by a third drive. The jaws are mounted on the lifting frame and are movable between lower and upper height positions such that for unloading the transport loading aid the at least one carrier is liftable by the jaws placed against the at least one carrier, and at least one tongue is at least partially slidable under the lifted at least one carrier to receive it in the receiving position. Further, an order fulfillment facility for picking carriers includes this transfer device.

Abstract: An embodiment includes use of a predictive model to ascertain a likelihood of a patient having expiratory flow limitation (EFL) to adjust the application of ventilator-based therapy. An embodiment may operate one or more predictive model on patient data alone to obtain a prediction of EFL for the patient, avoiding a need to perform invasive or ventilator based EFL detection, e.g., via a forced oscillation technique (FOT). An embodiment may be used in a system or method that adjusts ventilator settings for respiratory therapy, for example to abolish detected EFL in a patient having a positive classification for EFL.

Abstract: A system and method for operation of an autonomous vehicle (AV) yard truck is provided. A processor facilitates autonomous movement of the AV yard truck, and connection to and disconnection from trailers. A plurality of sensors are interconnected with the processor that sense terrain/objects and assist in automatically connecting/disconnecting trailers. A server, interconnected, wirelessly with the processor, that tracks movement of the truck around and determines locations for trailer connection and disconnection. A door station unlatches/opens rear doors of the trailer when adjacent thereto, securing them in an opened position via clamps, etc. The system computes a height of the trailer, and/or if landing gear of the trailer is on the ground and interoperates with the fifth wheel to change height, and whether docking is safe, allowing a user to take manual control, and optimum charge time(s). Reversing sensors/safety, automated chocking, and intermodal container organization are also provided.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: In a method for storing and picking stackable article carriers in an order fulfillment facility, in which transport loading aids are transported between a loading station with an automatically operated loading device, a storage zone and a removal station with an automatically operated unloading device by autonomously moveable, driverless transport vehicles, the transport loading aids are loaded with article carrier stacks in the loading station and the article carrier stacks are discharged from the transport loading aids in the unloading station. Subsequently, the article carriers for a picking order are reloaded onto one or multiple target loading aids. Further, an order fulfillment facility stores and stackable article carriers.

Abstract: The present invention is directed to a storage-stable formulation of long-chain RNA. In particular, the invention concerns a dry powder composition comprising a long-chain RNA molecule. The present invention is furthermore directed to methods for preparing a dry powder composition comprising a long-chain RNA molecule by spray-drying. The invention further concerns the use of such a dry powder composition comprising a long-chain RNA molecule in the preparation of pharmaceutical compositions and vaccines, to a method of treating or preventing a disorder or a disease, to first and second medical uses of such a dry powder composition comprising a long-chain RNA molecule and to kits, particularly to kits of parts, comprising such a dry powder composition comprising a long-chain RNA molecule.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: Methods and apparatus for managing the visual presentation of a back-end graphical flow model on a domain agnostic graphical flow interface are provided. An example method receives, from a back-end server, a back-end graphical flow node of a back-end graphical flow model additionally having one or more back-end graphical flow edges. An example method also presents at a graphical flow interface, a displayed node visual object representing the back-end graphical flow node. The method is configured to detect a user interaction with the displayed node visual object and transmit to the back-end server, a back-end graphical flow action message based at least in part on the user interaction. A back-end graphical flow update message comprising one or more back-end graphical flow update properties is received from the back-end server, causing an update to the visual presentation of the displayed node visual object.

Abstract: The invention provides a method for positioning a sensor over a target on a moveable object, comprising the following steps: a. moving the object to move the target to a desired position, b. moving the sensor in a direction towards a measured momentary position of the target, c. when the sensor is over the target. moving the sensor along with the target to the desired position of the target.

Abstract: Disclosed is an object table for holding an object, comprising: an electrostatic clamp arranged to clamp the object on the object table; a neutralizer arranged to neutralize a residual charge of the electrostatic clamp; a control unit arranged to control the neutralizer, wherein the residual charge is an electrostatic charge present on the electrostatic clamp when no voltage is applied to the electrostatic clamp.

Abstract: The present invention in particular relates to a method of producing an immunogenic composition exhibiting reduced virucidal activity, as well as to the immunogenic composition and uses thereof, wherein the method in particular comprises the steps of: (a) providing a mixture with a first liquid and a recombinant protein, (b) concentrating the recombinant protein in the mixture by removing a portion of the first liquid from the mixture, and (c) processing the solution resulting from step (b) by continuous diafiltration.

Abstract: Disclosed herein is a system for printing a three-dimensional object. The system can include at least one nozzle assembly configured to receive a continuous fiber and at least partially encase the continuous fiber with a polymer material to create a composite material. The nozzle assembly can also include a liquefier assembly that is operable coupled to a nozzle, which is configured to allow for the controlled deposit of the composite material while minimizing or eliminating tension exerted on the continuous fiber.

Abstract: The present invention concerns a potato protein composition comprising: patatin; and optionally insoluble fibers from potato and/or other potato proteins, wherein the protein, preferably the potato protein, has an aqueous solubility at pH=7.0 and 20° C. of at least 60%, and wherein the composition has an acetylcholinesterase (ACE) activity of less than 30 U/g, based on the dry weight of the protein, preferably the potato protein. The present invention further concerns a composition comprising fat or oil comprising at least one fatty acid group having 14 carbon atoms or less, and the said potato protein composition.

Abstract: Methods, devices, apparatus, systems and computer-readable storage media for assessing damages on vehicles are provided. In one aspect, a computer-implemented method includes: determining present damage data of at least one section of a vehicle based on an image of the at least one section of the vehicle using at least one machine learning model, comparing the present damage data of the at least one section of the vehicle to historical damage data of the at least one section of the vehicle to generate a comparison result, and determining whether there is a fraud event based on the comparison result. The present damage data includes information of a plurality of hail damage areas on the at least one section of the vehicle.

Abstract: A method for synthetically generating a point cloud of radar or LIDAR reflections, a reflection indicating at least one location at which radar or LIDAR interrogating radiation has been reflected. In the method, distribution functions which according to a random distribution provide samples in each case for at least one of the variables contained in the radar or LIDAR reflections are provided; synthetic reflections are generated by drawing samples in each case from the distribution functions for variables contained in the radar or LIDAR reflections, one of multiple distribution functions being selected according to at least one selection random distribution in order to draw each sample; the synthetic reflections are combined to form the sought point cloud.