Patents by Inventor Michael John Dipierro

Michael John Dipierro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of 4"-deoxyerythromycins A and B
    Patent number: 5760198
    Abstract: A process for the preparation of 4"-deoxyerythromycins, having the formula: ##STR1## wherein R is H or OH, and R.sup.1 is H or loweralkyl by treatment of the 2'-O-acetyl-4"-imidazolylthionocarbonyl-erythromycin starting material with the radical initiator 4,4'-azobis-(4-cyanovaleric acid), H.sub.3 PO.sub.2 and an organic base in a water-miscible solvent and optionally eliminating the 2'-O-acetyl group. In a preferred embodiment, the water-miscible solvent is an alcohol and the deoxygenation and deacetylation is carried out in one step.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: June 2, 1998
    Assignee: Abbott Laboratories
    Inventors: Shyamal I. Parekh, Alexandra E. Graham, Michael John Dipierro, Albert V. Thomas, David A. Riley