Patents by Inventor Michael John Dunkley
Michael John Dunkley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11484671Abstract: An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule.Type: GrantFiled: January 28, 2019Date of Patent: November 1, 2022Inventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Mark Glusker, Steve Paboojian
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Publication number: 20200197636Abstract: An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule.Type: ApplicationFiled: January 28, 2019Publication date: June 25, 2020Applicant: BGP Products Operations GmbHInventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Mark Glusker, Steve Paboojian
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Patent number: 10207066Abstract: An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule.Type: GrantFiled: April 9, 2004Date of Patent: February 19, 2019Assignee: BGP Products Operations GmbHInventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Mark Glusker, Steve Paboojian
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Patent number: 8069851Abstract: An aerosolization apparatus comprises a housing defining a chamber having a plurality of air inlets. The chamber contains an aerosolizable pharmaceutical formulation or is sized to receive a receptacle which contains an aerosolizable pharmaceutical formulation. A shield covers at least one of the air inlets or a portion of at least one of the air inlets. The shield prevents blockage of the air inlet by a user grasping the apparatus and inadvertently covering the air inlet. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the receptacle.Type: GrantFiled: June 22, 2009Date of Patent: December 6, 2011Assignee: Novartis AGInventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Sameer Shirgoankar
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Publication number: 20090260623Abstract: An aerosolization apparatus comprises a housing defining a chamber having a plurality of air inlets. The chamber contains an aersolizable pharmaceutical formulation or is sized to receive a receptacle which contains an aerosolizable pharmaceutical formulation. A shield covers at least one of the air inlets or a portion of at least one of the air inlets. The shield prevents blockage of the air inlet by a user grasping the apparatus and inadvertently covering the air inlet. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the receptacle.Type: ApplicationFiled: June 22, 2009Publication date: October 22, 2009Applicant: NOVARTIS PHARMA AGInventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Sameer Shirgoankar
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Patent number: 7559325Abstract: An aerosolization apparatus comprises a housing defining a chamber having a plurality of air inlets. The chamber contains an aersolizable pharmaceutical formulation or is sized to receive a receptacle which contains an aerosolizable pharmaceutical formulation. A shield covers at least one of the air inlets or a portion of at least one of the air inlets. The shield prevents blockage of the air inlet by a user grasping the apparatus and inadvertently covering the air inlet. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the receptacle.Type: GrantFiled: April 9, 2004Date of Patent: July 14, 2009Assignee: Novartis Pharma AGInventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon Harcourt, Sameer Shirgoankar
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Publication number: 20080115785Abstract: An inhaler for producing an inhalable aerosol of a powdered medicament includes an aerosolizing device in the form of a vortex chamber 1. The vortex chamber 1 has a tangential inlet port 3 and an axial port 2. The ratio of the diameter of the vortex chamber 1 to the diameter of the exit port 2 is between 4 and 12. The length of the exit port 2 is less than its diameter. The cross-section of the inlet port 3 is rectangular and is defined at the bottom and at the radially outermost edge by the walls of the vortex chamber 1. The cross-sectional area of the inlet conduit 7, which supplies the medicament in a gas flow to the inlet port 3, decreases in the direction towards the vortex chamber 1. The inlet conduit 7 may be curved. The inhaler is capable of repeatably producing an aerosol of a medicament with a high proportion of particles in the range 1 to 3 microns, while using a 20 relatively small amount of energy.Type: ApplicationFiled: October 31, 2007Publication date: May 22, 2008Applicant: Vectura Delivery Devices LimitedInventors: Stephen William Eason, Quentin John Harmer, Matthew Neil Sarkar, John Pinon, Michael John Dunkley, Roger William Clarke, Stephen Henry Hill
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Patent number: 6967002Abstract: A method and apparatus for producing a sterile medical solution is disclosed. The method includes providing at least two components, a first component including bicarbonate ions and a second component including glucose or calcium ions, preheating the first component to a first temperature and the second component to a second temperature, heat sterilizing the first and second components separately to a third and fourth temperatures respectively, the third and fourth temperatures being sterilizing temperatures for the first and second components, maintaining the first and second components approximately at their respective third and fourth temperatures, so as to sterilize the first and second components, cooling the first and second components and delivering the first and second components to a mixing device.Type: GrantFiled: April 4, 2000Date of Patent: November 22, 2005Assignee: Gambro Lundia ABInventors: Raymond Anthony Edgson, Michael John Dunkley, Richard J. Hammond, Eric Wilkinson
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Patent number: 6818179Abstract: Methods and apparatus for sterilizing heat sensitive fluids are provided. The methods include providing a first heat sensitive fluid component, providing a second fluid component, heating the second fluid component to a temperature greater than a predetermined sterilizing temperature, mixing the first heat sensitive fluid component with the heated second fluid component to heat the first heat sensitive fluid components and provide a mixed fluid at a temperature at least up to the predetermined sterilizing temperature, and maintaining the mixed fluid at that temperature for a predetermined sterilizing period. Apparatus for carrying out this method is also provided.Type: GrantFiled: April 15, 2002Date of Patent: November 16, 2004Assignee: Gambro Lundia ABInventors: Raymond Anthony Edgson, Michael John Dunkley, Richard J. Hammond, Eric Wilkinson
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Publication number: 20040215129Abstract: A method and apparatus for peritoneal dialysis are described The method includes draining a spent fluid from a patient into a second bag in a pressure chamber including a first bag for containing a fresh fluid for supply to a patient and a second bag for containing a spent fluid drained from a patient, by applying a reduced pressure to the second bag while weighing the first and second bags so as to control the draining of the spent fluid and supplying the fresh fluid to the first bag at a predetermined replenishment flow rate during draining of the spent fluid from the patient into the second bag independently of the influence of the reduced pressure. Apparatus for conducting such a method is also included.Type: ApplicationFiled: December 22, 2003Publication date: October 28, 2004Applicant: Gambro ABInventors: Raymond Anthony Edgson, Michael John Dunkley, Richard J. Hammond, Eric Wilkinson
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Publication number: 20040211419Abstract: An inhaler for producing an inhalable aerosol of a powdered medicament includes an aerosolising device in the form of a vortex chamber 1. The vortex chamer 1 has a tangential inlet port 3 and an axial port 2. The ratio of the diameter of the vortex chamber 1 to the diameter of the exit port 2 is between 4 and 12. The length of the exit port 2 is less than its diameter. The cross-section of the inlet port 3 is rectangular and is defined at the bottom and at the radially outermost edge by the walls of the vortex chamber 1. The cross-sectional area of the inlet conduit 7, which supplies the medicament in a gas flow to the inlet port 3, decreases in the direction towards the vortex chamber 1. The inlet conduit 7 may be curved. The inhaler is capable of repeatably producing an aerosol of a medicament with a high proportion of particles in the range 1 to 3 microns, while using a 20 relatively small amount of energy.Type: ApplicationFiled: June 17, 2004Publication date: October 28, 2004Inventors: Stephen William Eason, Quentin John Harmer, Michael John Dunkley, Matthew Neil Sarkar, John Pinon, Michael John Dunkley, Roger William Clarke, Stephen Henry Hill
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Patent number: 6579494Abstract: A device for preparing a sterile liquid includes structure for validating a sterilization treatment applied to the liquid. The validating structure includes structure for calculating, from at least one operating parameter of the device, a parameter representing a sterilizing value for the sterilization treatment, and structure for comparing the calculated parameter to a threshold value corresponding to the sterility of the liquid.Type: GrantFiled: March 29, 2000Date of Patent: June 17, 2003Assignee: Hospal IndustrieInventors: Jacques Chevallet, Thierry Court, Michael John Dunkley, Alain Frugier, Lennart Jonsson, Nicholas John Kerry, Hiram Rada, Jean-Louis Romarie
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Patent number: RE47526Abstract: An aerosolization apparatus comprises a housing defining a chamber having a plurality of air inlets. The chamber contains an aerosolizable pharmaceutical formulation or is sized to receive a receptacle which contains an aerosolizable pharmaceutical formulation. A shield covers at least one of the air inlets or a portion of at least one of the air inlets. The shield prevents blockage of the air inlet by a user grasping the apparatus and inadvertently covering the air inlet. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the receptacle.Type: GrantFiled: December 5, 2013Date of Patent: July 23, 2019Assignee: BGP ProductsInventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Sameer Shirgaonkar