Patents by Inventor Michael John Dunkley

Michael John Dunkley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200197636
    Abstract: An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule.
    Type: Application
    Filed: January 28, 2019
    Publication date: June 25, 2020
    Applicant: BGP Products Operations GmbH
    Inventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Mark Glusker, Steve Paboojian
  • Patent number: 10207066
    Abstract: An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule.
    Type: Grant
    Filed: April 9, 2004
    Date of Patent: February 19, 2019
    Assignee: BGP Products Operations GmbH
    Inventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Mark Glusker, Steve Paboojian
  • Patent number: 8069851
    Abstract: An aerosolization apparatus comprises a housing defining a chamber having a plurality of air inlets. The chamber contains an aerosolizable pharmaceutical formulation or is sized to receive a receptacle which contains an aerosolizable pharmaceutical formulation. A shield covers at least one of the air inlets or a portion of at least one of the air inlets. The shield prevents blockage of the air inlet by a user grasping the apparatus and inadvertently covering the air inlet. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the receptacle.
    Type: Grant
    Filed: June 22, 2009
    Date of Patent: December 6, 2011
    Assignee: Novartis AG
    Inventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Sameer Shirgoankar
  • Publication number: 20090260623
    Abstract: An aerosolization apparatus comprises a housing defining a chamber having a plurality of air inlets. The chamber contains an aersolizable pharmaceutical formulation or is sized to receive a receptacle which contains an aerosolizable pharmaceutical formulation. A shield covers at least one of the air inlets or a portion of at least one of the air inlets. The shield prevents blockage of the air inlet by a user grasping the apparatus and inadvertently covering the air inlet. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the receptacle.
    Type: Application
    Filed: June 22, 2009
    Publication date: October 22, 2009
    Applicant: NOVARTIS PHARMA AG
    Inventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Sameer Shirgoankar
  • Patent number: 7559325
    Abstract: An aerosolization apparatus comprises a housing defining a chamber having a plurality of air inlets. The chamber contains an aersolizable pharmaceutical formulation or is sized to receive a receptacle which contains an aerosolizable pharmaceutical formulation. A shield covers at least one of the air inlets or a portion of at least one of the air inlets. The shield prevents blockage of the air inlet by a user grasping the apparatus and inadvertently covering the air inlet. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the receptacle.
    Type: Grant
    Filed: April 9, 2004
    Date of Patent: July 14, 2009
    Assignee: Novartis Pharma AG
    Inventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon Harcourt, Sameer Shirgoankar
  • Publication number: 20080115785
    Abstract: An inhaler for producing an inhalable aerosol of a powdered medicament includes an aerosolizing device in the form of a vortex chamber 1. The vortex chamber 1 has a tangential inlet port 3 and an axial port 2. The ratio of the diameter of the vortex chamber 1 to the diameter of the exit port 2 is between 4 and 12. The length of the exit port 2 is less than its diameter. The cross-section of the inlet port 3 is rectangular and is defined at the bottom and at the radially outermost edge by the walls of the vortex chamber 1. The cross-sectional area of the inlet conduit 7, which supplies the medicament in a gas flow to the inlet port 3, decreases in the direction towards the vortex chamber 1. The inlet conduit 7 may be curved. The inhaler is capable of repeatably producing an aerosol of a medicament with a high proportion of particles in the range 1 to 3 microns, while using a 20 relatively small amount of energy.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 22, 2008
    Applicant: Vectura Delivery Devices Limited
    Inventors: Stephen William Eason, Quentin John Harmer, Matthew Neil Sarkar, John Pinon, Michael John Dunkley, Roger William Clarke, Stephen Henry Hill
  • Patent number: 6967002
    Abstract: A method and apparatus for producing a sterile medical solution is disclosed. The method includes providing at least two components, a first component including bicarbonate ions and a second component including glucose or calcium ions, preheating the first component to a first temperature and the second component to a second temperature, heat sterilizing the first and second components separately to a third and fourth temperatures respectively, the third and fourth temperatures being sterilizing temperatures for the first and second components, maintaining the first and second components approximately at their respective third and fourth temperatures, so as to sterilize the first and second components, cooling the first and second components and delivering the first and second components to a mixing device.
    Type: Grant
    Filed: April 4, 2000
    Date of Patent: November 22, 2005
    Assignee: Gambro Lundia AB
    Inventors: Raymond Anthony Edgson, Michael John Dunkley, Richard J. Hammond, Eric Wilkinson
  • Patent number: 6818179
    Abstract: Methods and apparatus for sterilizing heat sensitive fluids are provided. The methods include providing a first heat sensitive fluid component, providing a second fluid component, heating the second fluid component to a temperature greater than a predetermined sterilizing temperature, mixing the first heat sensitive fluid component with the heated second fluid component to heat the first heat sensitive fluid components and provide a mixed fluid at a temperature at least up to the predetermined sterilizing temperature, and maintaining the mixed fluid at that temperature for a predetermined sterilizing period. Apparatus for carrying out this method is also provided.
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: November 16, 2004
    Assignee: Gambro Lundia AB
    Inventors: Raymond Anthony Edgson, Michael John Dunkley, Richard J. Hammond, Eric Wilkinson
  • Publication number: 20040211419
    Abstract: An inhaler for producing an inhalable aerosol of a powdered medicament includes an aerosolising device in the form of a vortex chamber 1. The vortex chamer 1 has a tangential inlet port 3 and an axial port 2. The ratio of the diameter of the vortex chamber 1 to the diameter of the exit port 2 is between 4 and 12. The length of the exit port 2 is less than its diameter. The cross-section of the inlet port 3 is rectangular and is defined at the bottom and at the radially outermost edge by the walls of the vortex chamber 1. The cross-sectional area of the inlet conduit 7, which supplies the medicament in a gas flow to the inlet port 3, decreases in the direction towards the vortex chamber 1. The inlet conduit 7 may be curved. The inhaler is capable of repeatably producing an aerosol of a medicament with a high proportion of particles in the range 1 to 3 microns, while using a 20 relatively small amount of energy.
    Type: Application
    Filed: June 17, 2004
    Publication date: October 28, 2004
    Inventors: Stephen William Eason, Quentin John Harmer, Michael John Dunkley, Matthew Neil Sarkar, John Pinon, Michael John Dunkley, Roger William Clarke, Stephen Henry Hill
  • Publication number: 20040215129
    Abstract: A method and apparatus for peritoneal dialysis are described The method includes draining a spent fluid from a patient into a second bag in a pressure chamber including a first bag for containing a fresh fluid for supply to a patient and a second bag for containing a spent fluid drained from a patient, by applying a reduced pressure to the second bag while weighing the first and second bags so as to control the draining of the spent fluid and supplying the fresh fluid to the first bag at a predetermined replenishment flow rate during draining of the spent fluid from the patient into the second bag independently of the influence of the reduced pressure. Apparatus for conducting such a method is also included.
    Type: Application
    Filed: December 22, 2003
    Publication date: October 28, 2004
    Applicant: Gambro AB
    Inventors: Raymond Anthony Edgson, Michael John Dunkley, Richard J. Hammond, Eric Wilkinson
  • Patent number: 6579494
    Abstract: A device for preparing a sterile liquid includes structure for validating a sterilization treatment applied to the liquid. The validating structure includes structure for calculating, from at least one operating parameter of the device, a parameter representing a sterilizing value for the sterilization treatment, and structure for comparing the calculated parameter to a threshold value corresponding to the sterility of the liquid.
    Type: Grant
    Filed: March 29, 2000
    Date of Patent: June 17, 2003
    Assignee: Hospal Industrie
    Inventors: Jacques Chevallet, Thierry Court, Michael John Dunkley, Alain Frugier, Lennart Jonsson, Nicholas John Kerry, Hiram Rada, Jean-Louis Romarie
  • Patent number: RE47526
    Abstract: An aerosolization apparatus comprises a housing defining a chamber having a plurality of air inlets. The chamber contains an aerosolizable pharmaceutical formulation or is sized to receive a receptacle which contains an aerosolizable pharmaceutical formulation. A shield covers at least one of the air inlets or a portion of at least one of the air inlets. The shield prevents blockage of the air inlet by a user grasping the apparatus and inadvertently covering the air inlet. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the receptacle.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: July 23, 2019
    Assignee: BGP Products
    Inventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Sameer Shirgaonkar