Patents by Inventor Michael John Feldhaus

Michael John Feldhaus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for measuring relative amounts of nucleic acids in a complex mixture and retrieval of specific sequences therefrom
    Publication number: 20020172965
    Abstract: The present invention relates to a method for the comparative assessment of the level of specific nucleic acid sequences in samples derived from different sources. More specifically, the invention relates to a method using oligonucleotides covalently linked to a solid support, such as beads, to isolate specific labeled nucleic acid sequences from complex mixtures. The methods disclosed allow quantitative comparisons of the amount of nucleic acid of defined sequence in a plurality of different samples of nucleic acid, e.g., from different cells or tissues or from genetic libraries. Nucleic acids from the samples are labeled in such a fashion that the signals can be distinguished and compared following hybridization to the oligonucleotides on the beads. According to the invention, the solid supports with the hybridized nucleic acid may be retrieved, and the target nucleic acid eluted and analyzed.
    Type: Application
    Filed: February 1, 2002
    Publication date: November 21, 2002
    Applicant: Arcaris, Inc.
    Inventors: Carl Alexander Kamb, Michael John Feldhaus
  • Methods for measuring relative amounts of nucleic acids in a complex mixture and retrieval of specific sequences therefrom
    Patent number: 6060240
    Abstract: The present invention relates to a method for the comparative assessment of the level of specific nucleic acid sequences in samples derived from different sources. More specifically, the invention relates to a method using oligonucleotides covalently linked to a solid support, such as beads, to isolate specific labeled nucleic acid sequences from complex mixtures. The methods disclosed allow quantitative comparisons of the amount of nucleic acid of defined sequence in a plurality of different samples of nucleic acid, e.g., from different cells or tissues or from genetic libraries. Nucleic acids from the samples are labeled in such a fashion that the signals can be distinguished and compared following hybridization to the oligonucleotides on the beads. According to the invention, the solid supports with the hybridized nucleic acid may be retrieved, and the target nucleic acid eluted and analyzed.
    Type: Grant
    Filed: December 13, 1996
    Date of Patent: May 9, 2000
    Assignee: Arcaris, Inc.
    Inventors: Alexander Kamb, Michael John Feldhaus