Patents by Inventor Michael John Heffernan
Michael John Heffernan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11433396Abstract: In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel. Preferably, the hydrogel is heated before an assay is conducted with the cartridge, and pigmented beads in the wells indicate melting or excessive heating, or congealing of the hydrogel, based on pigment color change.Type: GrantFiled: August 5, 2020Date of Patent: September 6, 2022Assignee: Fannin Partners LLCInventors: Leo Linbeck, III, Dev Chatterjee, Michael John Heffernan
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Publication number: 20220192810Abstract: The present invention relates to the application of medical devices that manage urinary incontinence. The inter-bladder/urethra implanted device allows for passive urine leakage above a threshold bladder pressure and subject-controlled opening and closing of a valve to allow urine passage, below the threshold bladder pressure. The valve is preferably a deformable sac which seals against the interior of the urethra when closed. The valve can be opened by withdrawing slightly from the urethra surface. Passive urine leakage to prevent over-pressure can be facilitated by including external channels on the valve sac. In another embodiment, the valve sac has a central passage which expands and contracts for opening and closing, respectively.Type: ApplicationFiled: December 21, 2021Publication date: June 23, 2022Inventors: Leo LINBECK, III, Michael John Heffernan, Deepti Gopinath, Christine Luk, Carine Rizk, Amanda Gibbens
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Patent number: 11110459Abstract: In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel. Preferably, the hydrogel is heated before an assay is conducted with the cartridge, and pigmented beads in the wells indicate melting or excessive heating, or congealing of the hydrogel, based on pigment color change.Type: GrantFiled: November 13, 2018Date of Patent: September 7, 2021Assignee: Fannin Partners LLCInventors: Dev Chatterjee, Leo Linbeck, III, Michael John Heffernan
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Publication number: 20200393453Abstract: In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel.Type: ApplicationFiled: August 5, 2020Publication date: December 17, 2020Inventors: Dev Chatterjee, Leo Linbeck, III, Michael John Heffernan
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Patent number: 10828636Abstract: The invention relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. A microcomputer controls a stepping motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another, where the wells contain different assay reagents. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoded identifier to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient. Concurrently assaying a control allows modification of assay results based on measured field conditions.Type: GrantFiled: October 25, 2017Date of Patent: November 10, 2020Assignee: FANNIN PARTNERS LLCInventors: Leo Linbeck, III, Michael John Heffernan, Dev Chatterjee, Atul Varadhachary
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Patent number: 10737270Abstract: In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel. Preferably, the hydrogel is heated before an assay is conducted with the cartridge, and pigmented beads in the wells indicate melting or excessive heating, or congealing of the hydrogel, based on pigment color change.Type: GrantFiled: November 12, 2018Date of Patent: August 11, 2020Assignee: Fannin Partners, LLCInventors: Leo Linbeck, III, Michael John Heffernan, Dev Chatterjee
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Patent number: 10252268Abstract: The invention herein relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. The assay cartridge includes magnetic beads, sample and control solutions in some wells, and assay reagents in others. A microcomputer controls a DC motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoding to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient.Type: GrantFiled: December 26, 2016Date of Patent: April 9, 2019Assignee: Fannin Partners LLCInventors: Leo Linbeck, III, Michael John Heffernan, Dev Chatterjee
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Publication number: 20190091691Abstract: In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel.Type: ApplicationFiled: November 12, 2018Publication date: March 28, 2019Inventors: Dev Chatterjee, Leo Linbeck, III, Michael John Heffernan
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Publication number: 20190091692Abstract: In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel.Type: ApplicationFiled: November 13, 2018Publication date: March 28, 2019Inventors: Dev Chatterjee, Leo LlNBECK, III, Michael John Heffernan, Brad Ernest Munoz
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Patent number: 10195609Abstract: In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel. Preferably, the hydrogel is heated before an assay is conducted with the cartridge, and pigmented beads in the wells indicate melting or excessive heating, or congealing of the hydrogel, based on pigment color change.Type: GrantFiled: October 25, 2017Date of Patent: February 5, 2019Assignee: Fannin Partners, LLCInventors: Dev Chatterjee, Leo Linbeck, III, Michael John Heffernan, Brad Ernest Munoz, Atul Varadhachary
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Patent number: 10126297Abstract: The invention herein relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. The assay cartridge includes magnetic beads, sample and control solutions in some wells, and assay reagents in others. A microcomputer controls a stepping motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoded identifier to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient.Type: GrantFiled: October 25, 2017Date of Patent: November 13, 2018Assignee: Fannin Partners, LLCInventors: Dev Chatterjee, Leo Linbeck, III, Michael John Heffernan, Atul Varadhachary
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Publication number: 20180113126Abstract: The invention herein relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. The assay cartridge includes magnetic beads, sample and control solutions in some wells, and assay reagents in others. A microcomputer controls a stepping motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoded identifier to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient.Type: ApplicationFiled: October 25, 2017Publication date: April 26, 2018Inventors: Dev Chatterjee, Leo LlNBECK, III, Michael John Heffernan, Atul Varadhachary
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Publication number: 20180111128Abstract: In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel.Type: ApplicationFiled: October 25, 2017Publication date: April 26, 2018Inventors: Dev Chatterjee, Leo LlNBECK, III, Michael John Heffernan, Brad Ernest Munoz, Atul Varadhachary
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Publication number: 20180111123Abstract: The invention relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. A microcomputer controls a stepping motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another, where the wells contain different assay reagents. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoded identifier to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient. Concurrently assaying a control allows modification of assay results based on measured field conditions.Type: ApplicationFiled: October 25, 2017Publication date: April 26, 2018Inventors: Dev Chatterjee, Leo LlNBECK, III, Michael John Heffernan, Atul Varadhachary
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Publication number: 20170102384Abstract: The invention herein relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. The assay cartridge includes magnetic beads, sample and control solutions in some wells, and assay reagents in others. A microcomputer controls a DC motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoding to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient.Type: ApplicationFiled: December 26, 2016Publication date: April 13, 2017Inventors: Dev Chatterjee, Leo LlNBECK, III, Michael John Heffernan
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Patent number: 8252846Abstract: The present invention provides biodegradable particles (e.g., three-dimensional particles) and micelles which can be used to encapsulate active agents for delivering to a subject. The present invention further provides methods for producing and delivering such particles and micelles. Additionally, the invention provides vaccination strategies that encompass the use of the novel particles and micelles.Type: GrantFiled: March 12, 2008Date of Patent: August 28, 2012Assignees: Emory University, Georgia Tech Research Corporation, University of RochesterInventors: Niren Murthy, Bali Pulendran, Robert H. Pierce, Michael John Heffernan, Jihua Hao, Marcin Kwissa, Michael Davis, Stephen C. Yang
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Publication number: 20100062968Abstract: The present invention provides biodegradable particles (e.g., three-dimensional particles) and micelles which can be used to encapsulate active agents for delivering to a subject. The present invention further provides methods for producing and delivering such particles and micelles. Additionally, the invention provides vaccination strategies that encompass the use of the novel particles and micelles.Type: ApplicationFiled: May 10, 2006Publication date: March 11, 2010Inventors: Bali Pulendran, Niren Murthy, Robert H. Pierce, Michael John Heffernan, Jihua Hao, Marcin Kwissa
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Publication number: 20090011993Abstract: The present invention provides biodegradable particles (e.g., three-dimensional particles) and micelles which can be used to encapsulate active agents for delivering to a subject. The present invention further provides methods for producing and delivering such particles and micelles. Additionally, the invention provides vaccination strategies that encompass the use of the novel particles and micelles.Type: ApplicationFiled: March 12, 2008Publication date: January 8, 2009Inventors: Niren Murthy, Bali Pulendran, Robert H. Pierce, Michael John Heffernan, Jihua Hao, Marcin Kwissa, Michael Davis, Stephen C. Yang