Patents by Inventor Michael John McAdams
Michael John McAdams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220280081Abstract: Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test.Type: ApplicationFiled: August 17, 2020Publication date: September 8, 2022Inventors: Sayeed ANDESHMAND, Thomas H. CAULEY, III, John DIXON, David GLADE, Hédia MAAMAR, Michael John McADAMS, Dzam-Si Jesse NG, David Alexander ROLFE
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Publication number: 20210369160Abstract: Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test.Type: ApplicationFiled: April 14, 2021Publication date: December 2, 2021Inventors: Sayeed ANDESHMAND, Thomas H. CAULEY, III, John DIXON, David GLADE, Hédia MAAMAR, Michael John McADAMS, Dzam-Si Jesse NG, David Alexander ROLFE
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Publication number: 20210251540Abstract: Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test.Type: ApplicationFiled: November 2, 2020Publication date: August 19, 2021Inventors: Sayeed ANDESHMAND, Thomas H. CAULEY, III, John DIXON, David GLADE, Hédia MAAMAR, Michael John McADAMS, Dzam-Si Jesse NG, David Alexander ROLFE
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Patent number: 11008627Abstract: Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test.Type: GrantFiled: October 16, 2019Date of Patent: May 18, 2021Assignee: Talis Biomedical CorporationInventors: Sayeed Andeshmand, Thomas H. Cauley, III, John Dixon, David Glade, Hédia Maamar, Michael John McAdams, Dzam-Si Jesse Ng, David Alexander Rolfe
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Publication number: 20210047678Abstract: Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test.Type: ApplicationFiled: October 16, 2019Publication date: February 18, 2021Inventors: Sayeed ANDESHMAND, Thomas H. CAULEY, III, John DIXON, David GLADE, Hédia MAAMAR, Michael John McADAMS, Dzam-Si Jesse NG, David Alexander ROLFE
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Patent number: 10820847Abstract: Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test.Type: GrantFiled: October 16, 2019Date of Patent: November 3, 2020Assignee: Talis Biomedical CorporationInventors: Sayeed Andeshmand, Thomas H. Cauley, III, John Dixon, David Glade, Hédia Maamar, Michael John McAdams, Dzam-Si Jesse Ng, David Alexander Rolfe
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Patent number: 9322811Abstract: A fluidic connection system may comprise a port which includes a capillary tube receptacle with an end seal face and a threaded wall. The fluidic connection system may also comprise a capillary tube that includes a front end face for sealingly abutting against the end seal face of the port. On the capillary tube, a flange may be affixed at a distance from the front end face of the capillary tube. The fluidic connection system may further comprise a fitting nut that includes an axial hole to allow the capillary tube to pass therethrough and a matching threaded wall corresponding to the threaded wall of the port. The fitting nut may be slidably coupled with the capillary tube behind the flange. The distance at which the flange is affixed may be predetermined such that when the flange is pushed forward by the fitting nut, the front end face of the capillary tube abuts directly against the end seal face of the port.Type: GrantFiled: November 12, 2012Date of Patent: April 26, 2016Assignee: DIONEX CORPORATIONInventors: Michael John McAdams, Milton Liu, George N. Proper
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Patent number: 9188573Abstract: An ion chromatography housing for easy insertion and removal of a plurality of component cartridges is disclosed. Various components of the IC system are provided in the separate component cartridges. The IC housing includes a capillary separation column and may be connected to conventional-scale components of an IC system. A plurality of IC housings may be provided in a compartment with one or more separation columns. The columns may be capillary columns or conventional-scale columns. A method of using the ion chromatography system is also disclosed. The IC system may be utilized to perform two-dimensional ion chromatographic separation.Type: GrantFiled: January 20, 2010Date of Patent: November 17, 2015Assignee: DIONEX CORPORATIONInventors: Yan Liu, Glenn Masami Kuse, Victor Barreto, Gary L. Gleave, Christopher A. Pohl, William Dale Case, Khosro Moshfegh, Michael John McAdams
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Publication number: 20140130580Abstract: A fluidic connection system may comprise a port which includes a capillary tube receptacle with an end seal face and a threaded wall. The fluidic connection system may also comprise a capillary tube that includes a front end face for sealingly abutting against the end seal face of the port. On the capillary tube, a flange may be affixed at a distance from the front end face of the capillary tube. The fluidic connection system may further comprise a fitting nut that includes an axial hole to allow the capillary tube to pass therethrough and a matching threaded wall corresponding to the threaded wall of the port. The fitting nut may be slidably coupled with the capillary tube behind the flange. The distance at which the flange is affixed may be predetermined such that when the flange is pushed forward by the fitting nut, the front end face of the capillary tube abuts directly against the end seal face of the port.Type: ApplicationFiled: November 12, 2012Publication date: May 15, 2014Inventors: Michael John MCADAMS, Milton LIU, George N. PROPER
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Publication number: 20110174063Abstract: An ion chromatography housing for easy insertion and removal of a plurality of component cartridges is disclosed. Various components of the IC system are provided in the separate component cartridges. The IC housing includes a capillary separation column and may be connected to conventional-scale components of an IC system. A plurality of IC housings may be provided in a compartment with one or more separation columns. The columns may be capillary columns or conventional-scale columns. A method of using the ion chromatography system is also disclosed. The IC system may be utilized to perform two-dimensional ion chromatographic separation.Type: ApplicationFiled: January 20, 2010Publication date: July 21, 2011Applicant: Dionex CorporationInventors: Yan LIU, Glenn Masami Kuse, Victor Barreto, Gary L. Gleave, Christopher A. Pohl, William Dale Case, Khosro Moshfegh, Michael John McAdams
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Patent number: D881405Type: GrantFiled: October 23, 2018Date of Patent: April 14, 2020Assignee: Talis Biomedical CorporationInventors: Lance Gordon Hussey, Michael John McAdams, Sobha Pisharody, Marc Valer Serra, Shushuo Wu