Abstract: Provided herein are methods that include introducing into an inner ear of a mammal a therapeutically effective amount of an adeno-associated virus (AAV) vector that includes a nucleotide sequence encoding (a) a polypeptide including an antibody heavy chain variable domain operably linked to a signal peptide and a polypeptide including an antibody light chain variable domain operably linked to a signal peptide; (b) a polypeptide including an antigen-binding antibody fragment operably linked to a signal peptide; or (c) a soluble vascular endothelial growth factor receptor operably linked to a signal peptide.

Abstract: Disclosed herein are methods, an apparatus, and a computer-readable medium product for sharing broadcast resources and validating usage of the broadcast resources according to an agreement between a plurality of broadcast virtual network operators (BVNOs). A method includes determining the plurality of spectrum resources corresponding to a length of a broadcast frame, and creating a plurality of physical layer pipes (PLPs) based on a plurality of internet protocol (IP) flows from the plurality of BVNOs. The method includes constructing the broadcast frame including the plurality of PLPs and generating a broadcast frame record based on transmission of the broadcast frame. The broadcast frame record can identify the plurality of spectrum resources shared between the plurality of BVNOs. The method includes updating the broadcast frame record with identification information of the plurality of BVNOs and the plurality of IP flows corresponding to the plurality of PLPs of the broadcast frame.

Abstract: Systems and methods for relaying in broadcast single-frequency networks are disclosed herein. A single-frequency network can be formed in part using transmitters that receive data via a cooperative relay channel instead of a station-to-transmitter link. In some embodiments, a second channel may use a portion of its transmission time to relay the information to the single-frequency network transmitter using time-division multiplexing. In other embodiments, a second channel may encode the relayed information on a second layer using layer-division multiplexing.

Abstract: Disclosed herein are methods, an apparatus, and a computer-readable medium product for sharing broadcast resources and validating usage of the broadcast resources according to an agreement between a plurality of broadcast virtual network operators (BVNOs). A method includes determining the plurality of spectrum resources corresponding to a length of a broadcast frame, and creating a plurality of physical layer pipes (PLPs) based on a plurality of internet protocol (IP) flows from the plurality of BVNOs. The method includes constructing the broadcast frame including the plurality of PLPs and generating a broadcast frame record based on transmission of the broadcast frame. The broadcast frame record can identify the plurality of spectrum resources shared between the plurality of BVNOs. The method includes updating the broadcast frame record with identification information of the plurality of BVNOs and the plurality of IP flows corresponding to the plurality of PLPs of the broadcast frame.

Abstract: Systems and methods for relaying in broadcast single-frequency networks are disclosed herein. A single-frequency network can be formed in part using transmitters that receive data via a cooperative relay channel instead of a station-to-transmitter link. In some embodiments, a second channel may use a portion of its transmission time to relay the information to the single-frequency network transmitter using time-division multiplexing. In other embodiments, a second channel may encode the relayed information on a second layer using layer-division multiplexing.

Abstract: A time-temperature indicator device comprises a polymeric layer having a first and second surface and a dye composition adhered to said first surface comprising a dye which diffuses into the polymeric layer as a result of a cumulative time-temperature exposure wherein the polymeric layer is formed from a natural or synthetic rubber polymer or copolymer. The device may be attached to a product for monitoring cumulative time-temperature exposure.

Abstract: Photographic elements are disclosed in which exposure to at least one portion of the spectrum is recorded by a silver halide emulsion layer unit as an image having its optical density provided by silver. The layer unit is comprised of a plurality of radiation sensitive silver halide emulsion layers that are responsive to the same region of the spectrum, but differ in sensitivity, including a non-wandering silver halide reducing agent. A molar ratio of reducing agent to silver halide in one of the emulsion layers is less than that stoichiometrically required for complete silver halide reduction to silver. A higher molar ratio of reducing agent to silver halide is contained in a remaining of the two emulsion layers.

Abstract: Relief images can be formed in photographic elements having a tanning developing agent incorporated therein. The tanning developing agents have the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each an alkyl group of at least 3 carbon atoms, or an aryl group,After exposure, the material is treated with an alkaline solution and unhardened areas are removed.