Patents by Inventor Michael John TOWNSEND

Michael John TOWNSEND has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIAGNOSTIC AND THERAPEUTIC METHODS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS (RA)
    Publication number: 20250257407
    Abstract: The present invention provides prognostic, predictive, and therapeutic methods for the treatment of rheumatoid arthritis (RA). The invention is based, at least in part, on the discovery that the expression level of one or more biomarkers described herein in a sample (e.g., a synovial tissue sample, a synovial fluid sample, or a combination thereof) from an individual having RA can be used in methods of determining whether an individual having RA is likely to exhibit disease progression, identifying an individual having RA who is likely to respond to a treatment including a disease modifying anti-rheumatic drug (DMARD), predicting responsiveness of an individual having RA to a treatment including a DMARD, selecting a therapy for an individual having RA, and treating an individual having RA, as well as related kits.
    Type: Application
    Filed: May 2, 2025
    Publication date: August 14, 2025
    Inventors: Myles LEWIS, Costantino PITZALIS, Nandhini RAMAMOORTHI, Michael John TOWNSEND, Jason HACKNEY
  • Diagnostic and therapeutic methods for the treatment of rheumatoid arthritis (RA)
    Patent number: 12319965
    Abstract: The present invention provides prognostic, predictive, and therapeutic methods for the treatment of rheumatoid arthritis (RA). The invention is based, at least in part, on the discovery that the expression level of one or more biomarkers described herein in a sample (e.g., a synovial tissue sample, a synovial fluid sample, or a combination thereof) from an individual having RA can be used in methods of determining whether an individual having RA is likely to exhibit disease progression, identifying an individual having RA who is likely to respond to a treatment including a disease modifying anti-rheumatic drug (DMARD), predicting responsiveness of an individual having RA to a treatment including a DMARD, selecting a therapy for an individual having RA, and treating an individual having RA, as well as related kits.
    Type: Grant
    Filed: July 23, 2020
    Date of Patent: June 3, 2025
    Assignees: Genentech, Inc., Queen Mary University of London
    Inventors: Myles Lewis, Costantino Pitzalis, Nandhini Ramamoorthi, Michael John Townsend, Jason Hackney
  • DIAGNOSTIC AND THERAPEUTIC METHODS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS (RA)
    Publication number: 20200399703
    Abstract: The present invention provides prognostic, predictive, and therapeutic methods for the treatment of rheumatoid arthritis (RA). The invention is based, at least in part, on the discovery that the expression level of one or more biomarkers described herein in a sample (e.g., a synovial tissue sample, a synovial fluid sample, or a combination thereof) from an individual having RA can be used in methods of determining whether an individual having RA is likely to exhibit disease progression, identifying an individual having RA who is likely to respond to a treatment including a disease modifying anti-rheumatic drug (DMARD), predicting responsiveness of an individual having RA to a treatment including a DMARD, selecting a therapy for an individual having RA, and treating an individual having RA, as well as related kits.
    Type: Application
    Filed: July 23, 2020
    Publication date: December 24, 2020
    Applicants: Genentech, Inc., Queen Mary University of London, Queen Mary University of London
    Inventors: Myles LEWIS, Costantino PITZALIS, Nandhini RAMAMOORTHI, Michael John TOWNSEND, Jason HACKNEY