Abstract: An apparatus for cooling one or more samples includes a cryostat with a first wall forming an inner chamber with an opening for receiving the one or more samples. A second wall forms an outer chamber adapted to insulate the inner chamber and a channel leading to the opening of the inner chamber. A seal selectively seals the opening to the inner chamber, and a cryocooler thermally links to the inner chamber, such as by way of a flexible strap. The inner chamber may entirely surround the outer chamber, and yet via the channel allow for the removal of the one or more samples from the inner chamber while maintaining the evacuated outer chamber. The inner chamber may also be fully contained within the outer chamber, which may be evacuated. Related methods are also disclosed.

Abstract: Methods, apparatuses, and systems for transcribing and performing analysis on patient data are disclosed. Data is collected from one or more medical professionals as well as sensors and imaging devices positioned on or oriented towards a patient. An analysis is performed on the patient data and the data is presented to a medical professional via a verbal interface in a conversational manner, allowing the medical professional to provide additional data such as observations or instructions which may be used for further analysis or to perform actions related to the patient's care.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: A cocrystal having the formula LiX·aM, or a solvate or hydrate thereof, wherein X is a conjugate base of an organic acid, M is a neutral organic molecule, and a is from 0.5 to 4, pharmaceutical compositions comprising such cocrystals, cocrystal solvates, or cocrystal hydrates, and methods of preparing such cocrystals, cocrystal solvates, or cocrystal hydrates, and such pharmaceutical compositions.

Abstract: Methods and systems are disclosed for generating AR experiences. The methods and systems access a first component of a plurality of components implemented by the messaging application, the plurality of components comprising an AR experience, each of the plurality of components being configured to be separately launched by the messaging application. The methods and systems store a first state of the first component in a data structure that is shared across the plurality of components; launching. The methods and system launch, by the messaging application, a second component of the plurality of components in response to determining that an interaction has been performed using the first component; and configure a second state of the second component based on the interaction that has been performed using the first component.

Abstract: A system creating an autostereoscopic augmented reality (AR), virtual reality (VR), or other visual display experience involving 3D images, presented to a viewer without glasses or other head-gear. The system includes a projection screen, which includes a reflective surface formed using retroreflective material. The system includes a projection assembly and a beamsplitter, which is disposed between an outlet of the projection assembly and the projection screen. The system includes a physical scenic space facing a lower side of the beamsplitter and a viewing space facing an upper side of the beamsplitter. A controller operates the projector assembly to project left and right eye images toward the projection screen. The left and right eye images are then directed to left and right eye positions so a viewer with eyes positioned at the left and right eye positions perceives a virtual object concurrently with light from the physical scenic space.

Abstract: The present disclosure relates generally to the field of immunology, and particularly relates to compositions, methods, and systems for the analysis and generation of antigen-binding molecules produced by immune cells obtained from tissue samples (e.g., antibodies produced by B cells in tumor tissue samples or TCRs produced by T cells in tumor tissue samples) using spatial methodologies, and for the production and characterization of recombinant antigen-binding molecules (e.g., antibodies, TCRs) with desired properties.

Abstract: The present invention is directed to certain pyridopyrimidine and pyrimido[4,5-d]pyrimidine inhibitors of Kirsten rat sarcoma virus (KRAS) oncoproteins, and more particularly to compounds of Formula I as well as compositions comprising Formula I and methods of using the compound of Formula I for the treatment or prevention of a disease, disorder, or medical condition mediated through KRAS, especially the KRAS G12D oncoprotein.

Abstract: Presented herein are techniques for receiving a plurality of streams by an implantable component of an implantable medical device system from a plurality of wireless sources and mixing the plurality of streams to generate stimulation signals for use in stimulating a recipient of the implantable medical device system.

Abstract: A shelter system for a truck includes a platform assembly that can pivot back-and-forth between a stowed position and a deployed position. The platform assembly spans a bed of a truck when in the stowed position. The platform assembly is disposed over a cab of the truck when in the deployed position. A tent covers the platform assembly when the platform assembly is in the deployed position.

Abstract: A scanner arrangement for a temperature measurement system for measuring a temperature of a measured surface is disclosed. The scanner arrangement includes a first temperature sensor and a reference assembly. The reference assembly includes an opening including a reference surface, a second temperature sensor in contact with and for measuring the temperature of the reference surface, and a heater for heating the reference surface in accordance with control signals from a controller. The first temperature sensor has a field of view covering a portion of the measured surface and the reference surface. In embodiments, the temperature measurement system is integrated into a photo-thermal treatment unit providing a cooling air stream and laser energy, controlled by the controller. The opening and reference surface cooperate such that the reference surface is protected from direct exposure to the cooling air stream and the laser energy.

Abstract: A method of operating a gas turbine combustor includes: selectively directing fuel and a first air supply through a fuel nozzle assembly in a head end section to produce a first fuel/air mixture, which is ignited within a liner to produce combustion gases; selectively directing a second fuel/air mixture through the liner from at least one first injector disposed at a first axial location; selectively directing a third fuel/air mixture through the liner from at least one second injector disposed at a downstream, second axial location. Each of the fuel nozzle assembly, the first injector(s), and the second injector(s) receives only a respective air supply from a compressor discharge plenum. The second injector(s) receive a respective air supply that is greater than each of the respective air supplies of the fuel nozzle assembly and the first injector(s).

Abstract: Described herein are systems, devices, methods, and media for connecting a user for transmitting multimedia from electronic devices to emergency service providers. In some embodiments, a method for transmitting multimedia from an electronic device to an emergency service provider by an emergency management system includes the steps of: detecting an emergency alert indicative of an emergency; wherein each sensor within the set of pertinent sensors is determined to be associated with the emergency; obtaining a first set of multimedia contents from the set of pertinent sensors; determining, based on at least one of the set of pertinent sensors and the first set of multimedia contents, a set of relevant sensors from the set of pertinent sensors; and transmitting a second set of multimedia contents from the set of relevant sensors to an emergency service provider.

Abstract: A system and method for generating and transmitting emergency messages and for maintaining real-time emergency communications sessions between users and emergency dispatch centers. A system receives data transmitted from a user device and constructs an emergency message related to a specific type of emergency scenario as well as the location, meta-data and background information of the user. The generated emergency message is transmitted via a communications network and delivered to an appropriate emergency dispatch center. The method enables the user to deliver a detailed request for help regardless of his or her location or, in another instance, delivers the basic emergency response related information for the user. The generated emergency message is universally compatible with emergency communications center infrastructure so long as the communications centers possess basic voice call equipment.

Abstract: One embodiment of the present invention sets forth a technique for inserting content into a media program. The technique includes determining a plurality of markers corresponding to a plurality of locations within a media program. The technique also includes for each marker included in the plurality of markers, automatically analyzing a first set of intervals within the media program that lead up to the marker and a second set of intervals within the media program that immediately follow the marker and determine a set of audio characteristics associated with the first set of intervals and the second set of intervals. The technique further includes generating a plurality of scores for the plurality of markers based on the set of audio characteristics for each marker and inserting additional content at one or more markers included in the plurality of markers based on the plurality of scores.

Abstract: A component for a vehicle interior may comprise a composite structure comprising a fiber panel and a cover. The fiber panel may comprise a conductor. The conductor may provide a functional circuit for the composite structure. The conductor may comprise a pattern of electrically conductive threads. Conductive thread may be within the fiber panel. Conductive thread may be stitched into/onto the fiber panel. The conductor may comprise a stitch pattern comprising conductive thread comprising the functional circuit. The functional circuit may comprise a user interface, an input device, an output device, and/or a circuit element. The composite structure may comprise a resin structure for the fiber panel adjacent to the functional circuit. The component may comprise a trim panel, instrument panel, door panel, overhead panel, console, overhead console, floor console, interior trim component, pillar trim, operator control, steering control/wheel, etc.

Abstract: A visual perception device is described. The visual perception device has corrective optics for viewing virtual and real-world content. An insert for the corrective optics is attached using a magnetic set, pins and/or a nose piece. Interchangeable nose pieces allow for height adjustments to accommodate different users. The visual perception device has pliable components to absorb forces exerted on a nose piece and a protective barrier for limiting electric shock or ingress of dirt.

Abstract: A hose assembly for use with a tankless water heater. The hose assembly includes a flexible hose, a first connector assembly, and a second connector assembly. The first connector assembly is fluidly coupled with the flexible hose and includes a first fitting. The first fitting is rotatably coupled with the first connector assembly such that the first fitting is independently rotatable relative to the flexible hose. The second connector assembly is fluidly coupled with the flexible hose opposite to the first connector assembly.

Abstract: A ceiling tile system capable of mitigating radio-frequency and acoustic waves from passing therethrough including a set of conductive grid bars; and a set of ceiling tiles each having a layer of conductive material and a layer of acoustic insulation.