Abstract: The invention relates to novel derivatives of Interleukin-22 (IL-22), particularly those comprising a fatty acid covalently attached to an IL-22 protein, and their use in therapy.

Abstract: The present invention relates to new pharmaceutical agents, and to their use in the treatment of proliferative diseases, such as cancer (in particular, brain cancer).

Abstract: Disclosed herein are system, apparatus, article of manufacture, method and/or computer program product embodiments, and/or combinations and sub-combinations thereof, for a wireless media system including a wireless speaker device and a host device forming a peer-to-peer wireless network. The host device provides audio content to the speaker device, and the speaker device can decode and process the audio content received from the host device. The speaker device can be in various states that consume different level of powers, such as a standby state, a wake state, a connected state. The speaker device can determine the host device is in an inactive state or an active state. When the speaker device determines the host device is in an inactive state, the speaker device can enter the standby state, enable the communication circuit and the audio processing circuit of the speaker device to be in a low power state to save power.

Abstract: The present invention relates to a valve assembly configured to be arranged in a cylinder opening of a gas cylinder, comprising a valve housing having a first housing end and a second housing end, a first housing opening arranged at the first housing end and a second housing opening arranged at the second housing end, the first housing opening having an inner diameter, and a bore extending between the first housing opening and the second housing opening, the bore having an inner face, and an inner valve unit arranged in the bore, said inner valve unit having an inner valve housing, and a first end and a second end, the first end having an outer diameter, the outer diameter being larger than the inner diameter of the first housing opening, the first end being configured to abut the inner face at the first opening, whereby a filling valve is provided, the inner face of the first opening being a filling valve seat, the second end comprising an inlet to the inner valve unit, the inner valve unit further comprisin

Abstract: The present invention relates to a valve assembly configured to be arranged in a cylinder opening of a gas cylinder, comprising a valve housing having a first housing end and a second housing end, a first housing opening arranged at the first housing end and a second housing opening arranged at the second housing end, the first housing opening having an inner diameter, and a bore extending between the first housing opening and the second housing opening, the bore having an inner face, and an inner valve unit arranged in the bore, said inner valve unit having an inner valve housing, and a first end and a second end, the first end having an outer diameter, the outer diameter being larger than the inner diameter of the first housing opening, the first end being configured to abut the inner face at the first opening, whereby a filling valve is provided, the inner face of the first opening being a filling valve seat, the second end comprising an inlet to the inner valve unit, the inner valve unit further comprisin

Abstract: The present invention relates to a method for manufacturing an at least partly hollow MEMS structure. In a first step one or more through-going openings is/are provided in core material. The one or more through-going openings is/are then covered by an etch-stop layer. After this step, a bottom electrically conducting layer, one or more electrically conducting vias and a top electrically conducting layer are created. The bottom layer is connected to the vias and vias are connected to the top layer. The vias are formed by filling at least one of the one or more through-going openings. The method further comprises the step of creating bottom and top conductors in the respective bottom and top layers. Finally, excess core material is removed in order to create the at least partly hollow MEMS structure which may include a MEMS inductor.

Abstract: The present invention relates to a method for manufacturing an at least partly hollow MEMS structure. In a first step one or more through-going openings is/are provided in core material. The one or more through-going openings is/are then covered by an etch-stop layer. After this step, a bottom electrically conducting layer, one or more electrically conducting vias and a top electrically conducting layer are created. The bottom layer is connected to the vias and vias are connected to the top layer. The vias are formed by filling at least one of the one or more through-going openings. The method further comprises the step of creating bottom and top conductors in the respective bottom and top layers. Finally, excess core material is removed in order to create the at least partly hollow MEMS structure which may include a MEMS inductor.

Abstract: The system and method described herein may identify one or more virtual desktop extensions available in a cloud computing environment and launch virtual machine instances to host the available virtual desktop extensions in the cloud. For example, a virtual desktop extension manager may receive a virtual desktop extension request from a client desktop and determine whether authentication credentials for the client desktop indicate that the client desktop has access to the requested virtual desktop extension. In response to authenticating the client desktop, the virtual desktop extension manager may then launch a virtual machine instance to host the virtual desktop extension in the cloud and provide the client desktop with information for locally controlling the virtual desktop extension remotely hosted in the cloud.

Abstract: The system and method for determining fuzzy cause and effect relationships in an intelligent workload management system described herein may combine potential causes and effects captured from various different sources associated with an information technology infrastructure with substantially instantaneous feedback mechanisms and other knowledge sources. As such, fuzzy correlation logic may then be applied to the combined information to determine potential cause and effect relationships and thereby diagnose problems and otherwise manage interactions that occur in the infrastructure. For example, information describing potential causes and potential effects associated with an operational state of the infrastructure may be captured and combined, and any patterns among the information that describes the multiple potential causes and effects may then be identified.

Abstract: The system and method described herein may identify one or more virtual desktop extensions available in a cloud computing environment and launch virtual machine instances to host the available virtual desktop extensions in the cloud. For example, a virtual desktop extension manager may receive a virtual desktop extension request from a client desktop and determine whether authentication credentials for the client desktop indicate that the client desktop has access to the requested virtual desktop extension. In response to authenticating the client desktop, the virtual desktop extension manager may then launch a virtual machine instance to host the virtual desktop extension in the cloud and provide the client desktop with information for locally controlling the virtual desktop extension remotely hosted in the cloud.

Abstract: The system and method described herein may identify one or more virtual desktop extensions available in a cloud computing environment and launch virtual machine instances to host the available virtual desktop extensions in the cloud. For example, a virtual desktop extension manager may receive a virtual desktop extension request from a client desktop and determine whether authentication credentials for the client desktop indicate that the client desktop has access to the requested virtual desktop extension. In response to authenticating the client desktop, the virtual desktop extension manager may then launch a virtual machine instance to host the virtual desktop extension in the cloud and provide the client desktop with information for locally controlling the virtual desktop extension remotely hosted in the cloud.

Abstract: A system and method for a BP monitoring cuff that has an integrated acoustic sensor used to acquire Korotkoff sounds during partial occlusion of the arterial vessel.

Abstract: The system and method for determining fuzzy cause and effect relationships in an intelligent workload management system described herein may combine potential causes and effects captured from various different sources associated with an information technology infrastructure with substantially instantaneous feedback mechanisms and other knowledge sources. As such, fuzzy correlation logic may then be applied to the combined information to determine potential cause and effect relationships and thereby diagnose problems and otherwise manage interactions that occur in the infrastructure. For example, information describing potential causes and potential effects associated with an operational state of the infrastructure may be captured and combined, and any patterns among the information that describes the multiple potential causes and effects may then be identified.

Abstract: The present invention relates to a power generation system PGS comprising—a system intermediate output SIO, —a central controller CC, and—at least two DC/DC converters DD1, DD2, DDn each comprising—a power input PI1, PI2, PIn for connecting to an output of one or more solar cells SC1, SC2, SCn, —a control input CI1, CI2, CIn, and—a power output PO1, PO2, POn, wherein said power outputs PO1, PO2, POn of said at least two DC/DC converters DD1, DD2, DDn are coupled in series to establish an accumulated system output voltage or in parallel to establish an accumulated system output current, or a combination thereof, at said system intermediate output ISO, and wherein said central controller CC is arranged to be able to selectively set, via said control inputs CI1, CI2, CIn, an output state of each of at least two of said DC/DC converters DD1, DD2, DDn.

Abstract: The system and method described herein may identify one or more virtual desktop extensions available in a cloud computing environment and launch virtual machine instances to host the available virtual desktop extensions in the cloud. For example, a virtual desktop extension manager may receive a virtual desktop extension request from a client desktop and determine whether authentication credentials for the client desktop indicate that the client desktop has access to the requested virtual desktop extension. In response to authenticating the client desktop, the virtual desktop extension manager may then launch a virtual machine instance to host the virtual desktop extension in the cloud and provide the client desktop with information for locally controlling the virtual desktop extension remotely hosted in the cloud.

Abstract: The system and method for controlling cloud and virtualized data centers described herein may include a computing environment having a model-driven, service-oriented architecture for creating collaborative threads to manage workloads, and further to creating cloud images having embedded management agents and identity services for validating the cloud images prior to deployment into the cloud and virtualized data centers and controlling, monitoring, and auditing activity associated with the cloud images following deployment into the cloud and virtualized data centers.