Patents by Inventor Michael Joseph Mamounas

Michael Joseph Mamounas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPIES FOR TREATMENT OF BREAST CANCER
    Publication number: 20230088701
    Abstract: Provided are combination therapies comprising a PI3K inhibitor (e.g., inavolisib), a CDK4/6 inhibitor (e.g., palbociclib), and fulvestrant; and methods of treating hormone receptor positive and HER2 negative (HR+/HER2?) locally advanced or metastatic breast cancer in a patient (preferably a patient with a PIC3CA mutant patient) comprising administering a therapeutically effective amount of inavolisib, or a pharmaceutically acceptable salt thereof, a CDK4/6 inhibitor (e.g., palbociclib), and fulvestrant or letrozole.
    Type: Application
    Filed: June 3, 2022
    Publication date: March 23, 2023
    Applicant: Genentech, Inc.
    Inventors: Jennifer O'Hara Lauchle, Michael Joseph Mamounas, Jennifer Lee Schutzman, Lori Sickels Friedman, Jian Huang