Abstract: Described is a needle assembly system comprising a needle assembly including a needle and a needle support, and a cover including a distal portion adapted to house at least a distal end of the needle and a proximal portion adapted to house the needle support. The proximal portion includes a first portion and a second portion. The first portion has a first inner diameter substantially equal to an outer diameter of the needle support and the second portion has a second inner diameter greater than the diameter of the needle support.

Abstract: The present invention relates to a drug delivery device for dispensing of a dose of a medicinal product, comprising, a housing, a drive mechanism comprising an axially displaceable piston rod to act on a piston of a cartridge containing the medicinal product to be dispensed, wherein the housing is adapted to support a piercing element which is adapted to penetrate a distal end face of the cartridge exclusively on demand. Furthermore, the drug delivery device comprises means for displacing the cartridge from a proximal stop position to a distal stop position in an axial direction and with respect to the housing, wherein in the distal stop position, the cartridge is connected to the piercing element and wherein in the proximal stop position, the cartridge is disconnected from the piercing element such that a fluid transfer between inside volume of the cartridge and the piercing element is interrupted.

Abstract: A dermal access device for fluid injection comprising a bearing block for fixation of the device onto a patient's skin, a slider movably connected to the bearing block and a hollow needle arranged at the slider for puncturing the skin, wherein the needle creates a puncture angle with respect to the skin surface when puncturing the skin, which does not exceed 25°. A dermal access device for fluid injection comprising a bearing block for fixation of the device onto a patient's skin, a movable slider connected to the bearing block and a hollow needle arranged at the slider for puncturing the skin, wherein the device comprises a first stop for limiting a first moving direction of the slider at a first puncture position of the needle, where the device comprises a second stop at a second puncture position of the needle for limiting the second moving direction of the slider.

Abstract: A counter system for use in a drug delivery device is provided. The counter system comprises a counter element which is a foil, the counter element comprising indentations and indicia associated with the indentations, and a drive member provided with a catch for driving the counter element, wherein the catch engages a first indentation, and wherein, the catch is configured such that, when the drive member moves in a first direction, the counter element does not move and the catch disengages the first indentation and engages a second indentation which is arranged adjacent to the first indentation, and when the drive member moves in a second direction which is opposite to the first direction, the counter element also moves in the second direction.

Abstract: A cartridge holder for a drug delivery device is presented comprising a housing extending in an axial direction and being adapted to receive a cartridge at least partially filled with a medicament, said cartridge being sealed near a distal end by way of a pierceable seal. At least one bearing element is fixed to the housing, and at least one tensioning member is engaged with the bearing element and with the cartridge in an axial direction for transmitting a distally directed injection force from the cartridge to the housing.

Abstract: The present invention is directed at a dose setting mechanism for a drug delivery device, comprising an outer sleeve and an inner sleeve located at least partially within the outer sleeve wherein the outer sleeve is connected to the inner sleeve. To reduce noise excitations of the dose setting mechanism, at least one intermediate element is at least partially located in a clearance between the inner sleeve and the outer sleeve in such way that it reduces the relative movement of the inner sleeve and the outer sleeve along a play between the inner sleeve and the outer sleeve. The invention is further directed to a pen-type injector equipped with a respective dose setting mechanism.

Abstract: The present invention is directed to a method for assembling a drug delivery device with a drive mechanism and a bung movably provided in a cartridge. The drive mechanism includes a piston rod and a bearing for driving the bung in a distal direction, wherein the bearing and the piston rod are configured to be connected via a snap connection and wherein the contact between the drive mechanism and the bung is indicated by a detectable signal produced by the engaging snap connection. The method includes the steps of placing the bearing on the bung, displacing the piston rod towards the bearing such that the snap connection is established, monitoring for the signal and stopping displacement of the piston rod upon detection of the signal. The invention is further directed to drug delivery device produced according to the respective method.

Abstract: A cap for a drug delivery device is provided, the cap comprising a main body and at least one indication element which is moveably retained in the main body, wherein the indication element is configured to be moved from a first position to a second position with respect to the main body, and wherein an information indicated to a user by the cap is changed when the indication element is moved from the first position into the second position. Furthermore, a drug delivery device comprising the previously described cap and an interaction member is provided.

Abstract: The present invention is directed to a drug delivery device with a drive mechanism including a piston rod with a bearing for driving a bung in a cartridge in a distal direction. A movable element is disposed displacably in an axial direction within the drive mechanism. The moveable element is movable between a first position in which a distal end of said movable element protrudes from said bearing and a second position in which a distal end of said movable element lies flush with the distal end of said bearing. The invention is further directed to a method for detecting the contact between the bearing and the movable bung.

Abstract: Described is a needle assembly removal device comprising an inner portion, a channel formed in the inner portion, and an outer portion movably disposed on the inner portion. The channel has a proximal opening. Movement of the outer portion relative to the inner portion in a first direction causes the inner portion to change the proximal opening from a first width to a second width.

Abstract: The present invention is directed to a drug delivery device comprising a cartridge with a movable bung, a drive mechanism including a bearing for driving the bung in a distal direction for delivering a medicament and a piston rod for actuating the bearing. An electric conductor for transmitting an electrical signal is provided, wherein the electric conductor is configured such that a conductive connection is established or interrupted when the piston rod contacts the bearing or when the bearing contacts the bung. The invention is further directed to a method for detecting the contact between the drive mechanism and the movable bung.

Abstract: The present invention is directed to a method for detecting a contact between a drive mechanism and a bung in a drug delivery device. The bung is movably provided in a cartridge and the drive mechanism includes a piston rod and a bearing for driving the bung in a distal direction. The contact is indicated by a change in a vibration behavior, wherein the method includes the steps of inducing vibration excitations into the drug delivery device, displacing the piston rod relative to the bung such that a gap between the bearing and the bung is reduced and monitoring vibration of the drug delivery device. The invention is further directed to drug delivery device produced according to the respective method.

Abstract: A housing component of a drug delivery device to accommodate a drive mechanism, wherein the drive mechanism is operable to interact with a piston of a cartridge containing a medicinal product to be dispensed by the drug delivery device. The housing component comprises at least one radially inwardly extending flange portion to be operably engaged with a piston rod of the drive mechanism, wherein that the flange portion is at least partially structurally strengthened.

Abstract: The present invention relates to a medical device protection assembly and to a respective medical device. The protection assembly comprises at least one reorientation member being connectable with a medical device and being operable to orient the medical device into a predefined orientation in the event the medical device is subject to a free-fall.

Abstract: The present invention relates to a fastening assembly for a medical device and to a respective medical device, wherein the fastening assembly comprises a support structure and a device component releasably fastenable to the support structure by means of mutually corresponding fastening members being adapted to abrogate an interconnection of the device component and the support structure when becoming subject to a force effect or a mechanical impact above a predefined threshold.

Abstract: The present invention relates to a piston for a cartridge for a drug delivery device comprising: at least one annular sealing surface to radially abut against an inner side wall of a cartridge, a distal surface to confine a drug receiving volume of the cartridge, a thrust receiving surface adapted to receive a thrust exerting plunger of a drug delivery device for displacing the piston in a proximal direction relative to the side wall, wherein the thrust receiving surface comprises numerous centering elements protruding from the thrust receiving surface towards the plunger and wherein the centering elements comprise an outer shape and geometry that matches with a corresponding receptacle of the plunger, and wherein the centering elements are arranged and aligned on the circumference of an imaginary annular or circular structure.

Abstract: The present invention relates to a cartridge holder assembly for a drug delivery device as well as to such drug delivery device and to a corresponding method of assembly, wherein the cartridge holder assembly comprises: a cartridge holder (14; 40) adapted to receive a cartridge (12) to be filled with a medicinal product to be dispensed by the drug delivery device, wherein the cartridge holder (14; 40) comprises at least one through opening at a distal end section to receive a piercing element (20) being adapted to penetrate a sealing septum (22) of the cartridge (12), a constriction member (26; 42) being adapted to axially abut against the septum (22) and comprising a through opening (34; 52) to receive the piercing element (20), wherein said through opening (34; 52) is adjustable in diameter.

Abstract: The present invention relates to a cartridge holder assembly for a drug delivery device comprising of a cartridge holder adapted to receive a cartridge filled with a medicament to be dispensed by the drug delivery device, wherein the cartridge holder comprises a first through opening at a distal end section to receive a piercing element adapted to penetrate a sealing member of the cartridge, a support structure adjacently arranged to the first through opening; and a constriction member arranged between the support structure and a distal end face of the cartridge and having a second through opening smaller than the first through opening.

Abstract: The present invention relates to a housing for a drug delivery device, having a first housing component adapted to receive a cartridge at least partially filled with a medicament, and a second housing component adapted to receive a drive mechanism to operably engage with the cartridge for dispensing of a dose of the medicament, wherein the first housing component comprises an insert portion to be inserted in an axial direction into a corresponding receptacle of the second housing component, and wherein the insert portion comprises at least one radially outwardly extending first interlock member to positively engage and to rotationally lock with a correspondingly shaped second interlock member of the receptacle of the second housing component.

Abstract: A drive mechanism of a drug delivery device is presented having, a piston rod to operably engage with a piston of a cartridge containing a medicament, a first functional component and a second functional component whose position or orientation relative to each other is unambiguously correlated to a predefined axial position of the piston rod, wherein the first and/or the second functional component comprise at least one engaging portion to inseparably and to adhesively engage the first and the second functional component with each other for rendering the drive mechanism inoperable when the predefined axial position of the piston rod has been reached.