Patents by Inventor Michael Jung

Michael Jung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Device for regulating the passage of energy
    Patent number: 10114264
    Abstract: The present application relates to a device for regulating the passage of light through a light-transmitting area which comprises a switching layer comprising a liquid-crystalline medium comprising at least one dichroic dye, where the parameters degree of light transmission and degree of anisotropy of the device are selected in a certain manner.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: October 30, 2018
    Assignee: Merck Patent GmbH
    Inventors: Michael Junge, Andreas Beyer, Ursula Patwal
  • Device for regulating the passage of energy
    Patent number: 10108058
    Abstract: The present application relates to a device for regulating the passage of energy which is characterised in that it comprises at least two switching layers S(1) and S(2) arranged one behind the other, where the switching layers comprise a liquid-crystalline medium comprising at least one dichroic compound.
    Type: Grant
    Filed: April 9, 2014
    Date of Patent: October 23, 2018
    Assignee: Merck Patent GmbH
    Inventors: Michael Junge, Andreas Beyer, Ursula Patwal
  • Diarylhydantoin Compounds
    Publication number: 20180086718
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: July 20, 2017
    Publication date: March 29, 2018
    Applicant: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael Jung, Charlie D. Chen, Samedy Ouk, Derek Welsbie, Chris Tran, John Wongvipat, Dongwon Yoo
  • Cutting tool
    Patent number: 9902043
    Abstract: A cutting tool includes a plurality of cut-off wheels which are arranged alongside one another coaxially along a common rotation axis. Each of the plurality of cut off wheels comprises a blade body which comprises a plurality of cutting segments distributed around a circumference of the blade body, each blade body defining a central cutting plane. Some of the plurality of cutting segments are configured to protrude axially out of the central cutting plane. The plurality of cutting segments are arranged so that a segment gap exists between two cutting segments arranged adjacent to one another in a direction of rotation. At least a first of the plurality of cutting segments arranged in a first axial position is configured to be larger than a second of the plurality of cutting segments arranged in a second axial position which differs from the first axial position.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: February 27, 2018
    Assignee: RHODIUS SCHLEIFWERKZEUGE GMBH & CO. KG
    Inventor: Michael Jung
  • TRICYCLIC GYRASE INHIBITORS
    Publication number: 20170369498
    Abstract: Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.
    Type: Application
    Filed: July 7, 2017
    Publication date: December 28, 2017
    Applicants: Merck Sharp & Dohme Corp., LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Daniel Bensen, Zhiyong Chen, John Finn, Thanh T. Lam, Suk J. Lee, Xiaoming Li, Douglas W. Phillipson, Leslie W. Tari, Michael Trzoss, Junhu Zhang, Felice C. Lightstone, Toan B. Nguyen, Sergio E. Wong, Paul Aristoff, Michael Jung
  • METHOD, SYSTEM AND APPARATUS FOR MANAGING COMMUNICATION SESSIONS USING JOINT STORAGE
    Publication number: 20170244842
    Abstract: According to embodiments described in the specification, a method, system and apparatus for managing communication sessions using joint storage. One of a policy server and a charging server, connected to each other via a core mobile network, stores a database containing both charging data and policy data. The other of the policy server and the charging server, rather than maintaining a distinct database, routes read and write operations to the server storing the database.
    Type: Application
    Filed: October 10, 2014
    Publication date: August 24, 2017
    Inventor: Michael JUNG
  • Tricyclic gyrase inhibitors
    Patent number: 9732083
    Abstract: Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: August 15, 2017
    Assignees: MERCK SHARP & DOHME CORP., LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Daniel Bensen, Zhiyong Chen, John Finn, Thanh To Lam, Suk Joong Lee, Xiaoming Li, Douglas W. Phillipson, Leslie William Tari, Michael Trzoss, Junhu Zhang, Felice C. Lightstone, Toan B. Nguyen, Sergio E. Wong, Paul Aristoff, Michael Jung
  • Liquid-crystalline medium
    Patent number: 9701905
    Abstract: The application relates to a liquid-crystalline medium comprising at least one dichroic dye having a rylene structure which absorbs red light. The application furthermore relates to a device, preferably a device for the regulation of the passage of energy through a light-transmitting area, which contains the liquid-crystalline medium.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: July 11, 2017
    Assignee: Merck Patent GmbH
    Inventors: Michael Junge, Andreas Beyer, Ursula Patwal, Peer Kirsch, Susann Beck, Casper Laurens Van Oosten, Felix Fritz Rudolf Schlosser
  • Liquid crystalline medium and liquid crystal device
    Patent number: 9650573
    Abstract: The present invention relates a liquid crystalline medium comprising one or more liquid crystalline compounds, one or more dichroic dyes, and one or more compounds capable of promoting or inducing homeotropic alignment to the adjacent liquid crystal medium at a given temperature selected from the group of compounds (A), having a three-dimensional structure, a molecular weight of greater than 450 Da, and one or more anchor groups, or the group of organic compounds (B) having one or more ring groups, and one or more anchor groups. The invention furthermore relates to a temperature-reactive device for the regulation of light transmission, containing such liquid crystalline medium, and a process for the temperature-dependent control of light transmission through the layer of such liquid-crystalline medium.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: May 16, 2017
    Assignee: Merck Patent GmbH
    Inventors: Graziano Archetti, Michael Junge, Ming-Chou Wu
  • Switch element comprising a liquid-crystalline medium
    Patent number: 9617473
    Abstract: The present invention relates to a switch element, which is thermoresponsive and which switches between a less transmissive state for radiant energy and a more transmissive state for radiant energy, and which comprises a liquid-crystalline medium. The invention furthermore relates to the use of the switch element for the regulation of radiant energy flow between interior spaces and the environment and for the regulation of the temperature of interior spaces. The invention furthermore relates to a liquid-crystalline medium, characterised in that it comprises 5-95% of a compound of the formula (I), in particular for use in the switch elements according to the invention.
    Type: Grant
    Filed: July 27, 2011
    Date of Patent: April 11, 2017
    Assignee: Merck Patent GmbH
    Inventor: Michael Junge
  • Device for regulating the passage of energy
    Patent number: 9535271
    Abstract: The present invention relates to a device for regulating the passage of energy through a light-transmitting area, comprising a first polarization layer, a second polarization layer and a switching layer which is arranged between the two polarization layers and changes the polarization properties of polarized light as a function of temperature, where the two polarization layers are characterized by a suitable choice of their transmission in the transmission direction and their degree of polarization. The invention furthermore relates to a process for the production of the device according to the invention and to the use of the device for influencing light transmission and/or the passage of energy into an interior as a function of temperature.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: January 3, 2017
    Assignee: MERCK PATENT GMBH
    Inventors: Michael Junge, Andreas Beyer
  • Switch element comprising a liquid crystalline medium
    Patent number: 9507185
    Abstract: The invention relates to a temperature-controlled switching element for the regulation of light transmission. The invention furthermore relates to a mixture comprising at least one liquid-crystalline compound, at least one monomer compound which represents a monofunctional compound, and at least one monomer compound which represents a multifunctional compound. The invention again furthermore relates to the use of the said mixture for the production of the switching element according to the invention.
    Type: Grant
    Filed: September 25, 2012
    Date of Patent: November 29, 2016
    Assignee: Merck Patent GmbH
    Inventors: Michael Junge, Andreas Beyer
  • METHODS AND COMPOSITIONS FOR DELIVERY OF ACTIVE AGENTS
    Publication number: 20160250354
    Abstract: A lipid particle can include a cationic lipid. The cationic lipid can include one or more hydrophobic tails, which can include one or more sites of unsaturation. The sites of unsaturation can include cycloalkyl groups, e.g., cyclopropyl, cyclobutyl, cyclopentyl, or cyclohexyl groups. The lipid particle is suitable for delivering an active agent.
    Type: Application
    Filed: January 29, 2016
    Publication date: September 1, 2016
    Applicant: TEKMIRA PHARMACEUTICALS CORPORATION
    Inventors: Muthiah Manoharan, Kallanthotthathil Rajeev, Muthusamy Jayaraman, Michael Jung
  • Optical switch element comprising a liquid-crystalline medium
    Patent number: 9416314
    Abstract: The present invention relates to an optical switch element, comprising a liquid-crystalline medium for the temperature-dependent regulation of radiant energy flow. The invention furthermore relates to the use of the optical switch element for the regulation of radiant energy flow between interior spaces and the environment and for the regulation of the temperature of interior spaces. The invention furthermore relates to a liquid-crystalline medium, characterized in that it comprises 5-95% of a compound of the formula (I), in particular for use in the optical switch elements according to the invention.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: August 16, 2016
    Assignee: Merck Patent GmbH
    Inventor: Michael Junge
  • SURGICAL GUIDANCE SYSTEMS, DEVICES, AND METHODS
    Publication number: 20160220314
    Abstract: Surgical systems and methods for avoiding injury to an anatomical structure are disclosed. According to some aspects, an implantable device configured to emit a detectable field may be attached to the anatomical structure. A proximity sensor may be attached to a distal end of a surgical instrument and may be configured to detect the detectable field. A control unit in communication with the proximity sensor may be configured to use the proximity sensor to determine if the distal end of the surgical instrument is within a predetermined distance of the implantable device. If so, a notification such as a vibration or alarm may be provided to a user of the surgical instrument so that the user can maneuver the surgical instrument to limit or prevent contact with the anatomical structure.
    Type: Application
    Filed: March 12, 2015
    Publication date: August 4, 2016
    Inventors: Justin Huelman, Andrew Wu, Michael Jung, Marc Child, Vidit Sharma, Addason Mccaslin
  • CUTTING TOOL
    Publication number: 20160221154
    Abstract: A cutting tool includes a plurality of cut-off wheels which are arranged alongside one another coaxially along a common rotation axis. Each of the plurality of cut off wheels comprises a blade body which comprises a plurality of cutting segments distributed around a circumference of the blade body, each blade body defining a central cutting plane. Some of the plurality of cutting segments are configured to protrude axially out of the central cutting plane. The plurality of cutting segments are arranged so that a segment gap exists between two cutting segments arranged adjacent to one another in a direction of rotation. At least a first of the plurality of cutting segments arranged in a first axial position is configured to be larger than a second of the plurality of cutting segments arranged in a second axial position which differs from the first axial position.
    Type: Application
    Filed: September 9, 2014
    Publication date: August 4, 2016
    Applicant: RHODIUS SCHLEIFWERKZEUGE GMBH & CO. KG
    Inventor: MICHAEL JUNG
  • OXYSTEROLS THAT ACTIVATE LIVER X RECEPTOR SIGNALING AND INHIBIT HEDGEHOG SIGNALING
    Publication number: 20160206631
    Abstract: This invention relates, e.g., to compositions comprising oxysterol compounds represented by Formula I or Formula II, e.g., comprising one or more of Oxy 16, Oxy 22, Oxy30, Oxy 31, Oxy35, Oxy37, Oxy43, Oxy44, Oxy45 or Oxy47. The compounds are shown to be Hedgehog pathway inhibiting, and to act as agonists for liver X receptor (LXR). Also disclosed are methods of using compositions of the invention to inhibit Hedgehog signaling effects, such as cell proliferation, including treating subjects in need thereof, and pharmaceutical compositions and kits for implementing methods of the invention.
    Type: Application
    Filed: November 18, 2015
    Publication date: July 21, 2016
    Applicants: JOHNS HOPKINS UNIVERSITY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Farhad PARHAMI, Michael JUNG, Khanhlinh NGUYEN, Dongwon YOO, William MATSUI
  • Switch element comprising a liquid-crystalline medium
    Patent number: 9371483
    Abstract: The present invention relates to a switch element, which is thermoresponsive and which switches between a less transmissive state for radiant energy and a more transmissive state for radiant energy, and which comprises a liquid-crystalline medium. The invention furthermore relates to the use of the switch element for the regulation of radiant energy flow between interior spaces and the environment and for the regulation of the temperature of interior spaces. The invention furthermore relates to a liquid-crystalline medium, characterized in that it comprises 5-60% of a compound of the formula (I), in particular for use in the switch elements according to the invention.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: June 21, 2016
    Assignee: MERCK PATENT GMBH
    Inventor: Michael Junge
  • Spraygun for producing cured coating films and methods of use thereof
    Patent number: 9339832
    Abstract: Described is a method and an apparatus for producing cured coating films on a substrate surface. Specifically, a portable spraygun may be used to initiate radiation cure without the operative having to be protected from radiation. The spraygun comprises a supply channel for a radiation-curable coating composition, a needle, a reserve for the radiation-curable coating composition, and, optionally, a supply channel for a gas.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: May 17, 2016
    Assignee: BASF SE
    Inventors: Wolfgang Schrof, Thomas Meier, Christian Michael Jung, Antoine Carroy, Werner-Alfons Jung, Peter Hoffmann, Tobias Hintermann, Caroline Lordelot, Olof Wallquist
  • Premature-termination-codons readthrough compounds
    Patent number: 9255088
    Abstract: Premature termination codons readthrough compounds, composition thereof, and methods of making and using the same are provided.
    Type: Grant
    Filed: February 11, 2013
    Date of Patent: February 9, 2016
    Assignee: The Regents of the University of California
    Inventors: Richard Gatti, Liutao Du, Robert Damoiseaux, Chih-Hung Lai, Michael Jung, Jin-Mo Ku, Carmen Bertoni