Patents by Inventor Michael Justus

Michael Justus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of making a diisocyanate terminated macromer
    Publication number: 20060281874
    Abstract: A novel macromer or mixture thereof is described herein, comprising benzoyl isocyanate terminal moieties and at least two residues of a water-soluble polymer having a molecular weight ranging from 80 to 10,000 adjacent to the carbonyl group of the benzoyl isocyanate moieties, thereby forming at least two ester linkages in the macromer or mixture thereof. A method for making a diisocyanate macromer is also described herein.
    Type: Application
    Filed: June 28, 2006
    Publication date: December 14, 2006
    Inventors: Benjamin Fitz, Michael Justus, Christopher Westergom
  • Method of making iron(III)gluconate complex
    Publication number: 20060069276
    Abstract: The present invention refers to a method for making iron(III)gluconate complex, preferably alkali iron(III)gluconate complex. The method includes the following steps: (i) mixing a water soluble iron(III)salt in aqueous solution, simultaneously or in any desired sequence, with a member selected from gluconic acid, a water soluble salt of gluconic acid and combinations thereof, and a member selected from an alkali hydroxide, an alkali carbonate, an alkali hydrogen carbonate and combinations thereof, so that the reaction mixture has an acid value (pH-value) within the range of from 7.0 to 12, provided that when alkali hydroxide is used, gluconic acid or a water soluble salt of gluconic acid is provided at the beginning of the reaction or is added to the reaction mixture simultaneously with the alkali hydroxide; (ii) heating the reaction mixture until the iron(III)gluconate complex has formed; and (iii) adding an organic solvent which is miscible with water until the iron(III)gluconate complex is precipitated.
    Type: Application
    Filed: November 14, 2005
    Publication date: March 30, 2006
    Inventors: Michael Justus, Rolf Hanseler
  • Method of making iron(III)gluconate complex
    Patent number: 7005531
    Abstract: The present invention refers to a method for making iron(III)gluconate complex, preferably alkali iron(III)gluconate complex. The method includes the following steps: (i) mixing a water soluble iron(III)salt in aqueous solution, simultaneously or in any desired sequence, with a member selected from gluconic acid, a water soluble salt of gluconic acid and combinations thereof, and a member selected from an alkali hydroxide, an alkali carbonate, an alkali hydrogen carbonate and combinations thereof, so that the reaction mixture has an acid value (pH-value) within the range of from 7.0 to 12, provided that when alkali hydroxide is used, gluconic acid or a water soluble salt of gluconic acid is provided at the beginning of the reaction or is added to the reaction mixture simultaneously with the alkali hydroxide; (ii) heating the reaction mixture until the iron(III)gluconate complex has formed; and (iii) adding an organic solvent which is miscible with water until the iron(III)gluconate complex is precipitated.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: February 28, 2006
    Assignee: Cilag AG
    Inventors: Michael Justus, Rolf Hänseler
  • Method of making iron(III)gluconate complex
    Publication number: 20050256328
    Abstract: The present invention refers to a method for making iron(III)gluconate complex, preferably alkali iron(III)gluconate complex. The method includes the following steps: (i) mixing a water soluble iron(III)salt in aqueous solution, simultaneously or in any desired sequence, with a member selected from gluconic acid, a water soluble salt of gluconic acid and combinations thereof, and a member selected from an alkali hydroxide, an alkali carbonate, an alkali hydrogen carbonate and combinations thereof, so that the reaction mixture has an acid value (pH-value) within the range of from 7.0 to 12, provided that when alkali hydroxide is used, gluconic acid or a water soluble salt of gluconic acid is provided at the beginning of the reaction or is added to the reaction mixture simultaneously with the alkali hydroxide; (ii) heating the reaction mixture until the iron(III)gluconate complex has formed; and (iii) adding an organic solvent which is miscible with water until the iron(III)gluconate complex is precipitated.
    Type: Application
    Filed: November 18, 2004
    Publication date: November 17, 2005
    Inventors: Michael Justus, Rolf Hanseler
  • Process for preparing [S-(R*,S*)]-&bgr;-[[[1-[1-oxo-3(4-piperidinyl)propyl]-3-piperidinyl]carbonyl]amino]-3-pyridinepropanoic acid and derivatives
    Patent number: 6515130
    Abstract: A process for preparing a compound of formula I wherein R1 and R2 are independently selected from the group consisting of hydrogen, lower alkyl and halogen
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: February 4, 2003
    Inventors: Judith H. Cohen, Michael Justus, Cynthia A. Maryanoff, Armin Rössler, Fridtjof Schröder, Kirk L. Sorgi, Frank J. Villani, Jr., Christian Weh
  • Process for preparing [S- (R*, S*) ] -beta- [ [ [1- [1-oxo-3- (4-piperidinyl) propyl] -3-piperidinyl] carbonyl]amino] -3-pyridinepropanoic acid and derivatives
    Publication number: 20020137937
    Abstract: A process for preparing a compound of formula I 1
    Type: Application
    Filed: February 22, 2002
    Publication date: September 26, 2002
    Inventors: Judith H. Cohen, Michael Justus, Cynthia A. Maryanoff, Armin Rossler, Fridtjof Harmen Schroder, Kirk L. Sorgi, Frank J. Villani, Christian Weh