Patents by Inventor Michael K. Bamat

Michael K. Bamat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF CHEMOTHERAPEUTIC AGENT AND ANTIVIRAL AGENT TOXICITY WITH ACYLATED PYRIMIDINE NUCLEOSIDES
    Publication number: 20010025032
    Abstract: The subject invention discloses compounds, compositions and methods for treatment and prevention of toxicity due to chemotherapeutic agents and antiviral agents. Disclosed are acylated derivatives of non-methylated pyrimidine nucleosides. These compounds are capable of attenuating damage to the hematopoietic system in animals receiving antiviral or antineoplastic chemotherapy.
    Type: Application
    Filed: February 16, 1999
    Publication date: September 27, 2001
    Inventors: REID W. VON BORSTEL, MICHAEL K. BAMAT
  • Pyrimidine nucleotide precursors for treatment of systemic inflammation and inflammatory hepatitis
    Patent number: 6232298
    Abstract: Pyrimidine nucleotide precursors including acyl derivatives of cytidine, uridine, and orotate, and uridine phosphorylase inhibitors, and their use in enhancing resistance to sepsis or systemic inflammation are disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 15, 2001
    Assignee: Pro-Neuron, Inc.
    Inventors: Reid W. von Borstel, Michael K. Bamat, Bradley M. Hiltbrand
  • Enhancing blood cell count with oxypurine nucleosides
    Patent number: 6060459
    Abstract: The invention relates to certain oxypurine nucleosides, congeners of such oxypurine nucleosides, and acyl derivatives thereof, and compositions which contain at least one of these compounds. The invention also relates to methods of treating or preventing hematopoietic disorders and modifying hematopoiesis, and treating or preventing inflammatory diseases and bacterial infections by administering a compound or composition of the present invention to an animal.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: May 9, 2000
    Assignee: Pro-Neuron, Inc.
    Inventors: Reid W. von Borstel, Michael K. Bamat, Bradley M. Hiltbrand, James C. Butler, Shyam Shirali
  • Oxypurine nucleosides and their congeners, and acyl derivatives thereof, for improvement of hematopoiesis
    Patent number: 6054441
    Abstract: The invention relates to certain oxypurine nucleosides, congeners of such oxypurine nucleosides, and acyl derivatives thereof, and compositions which contain at least one of these compounds. The invention also relates to methods of treating or preventing hematopoietic disorders and modifying hematopoiesis, and treating or preventing inflammatory diseases and bacterial infections by administering a compound or composition of the present invention to an animal.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: April 25, 2000
    Assignee: Pro-Neuron, Inc.
    Inventors: Reid W. von Borstel, Michael K. Bamat, Bradley M. Hiltbrand, James C. Butler, Shyam Shirali
  • Treatment of chemotherapeutic agent and antiviral agent toxicity with acylated pyrimidine nucleosides
    Patent number: 5968914
    Abstract: The subject invention discloses compounds, compositions and methods for treatment and prevention of toxicity due to chemotherapeutic agents and antiviral agents. Disclosed are acylated derivatives of non-methylated pyrimidine nucleosides. These compounds are capable of attenuating damage to the hematopoietic system in animals receiving antiviral or antineoplastic chemotherapy.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 19, 1999
    Assignee: Pro-Neuron, Inc.
    Inventors: Reid von Borstel, Michael K. Bamat
  • Compositions of chemotherapeutic agent or antiviral agent with acylated pyrimidine nucleosides
    Patent number: 5736531
    Abstract: The subject invention discloses compounds, compositions and methods for treatment and prevention of toxicity due to chemotherapeutic agents and antiviral agents. Disclosed are acylated derivatives of non-methylated pyrimidine nucleosides. These compounds are capable of attenuating damage to the hematopoietic system in animals receiving antiviral or antineoplastic chemotherapy.
    Type: Grant
    Filed: December 30, 1993
    Date of Patent: April 7, 1998
    Assignee: Pro-Neuron, Inc.
    Inventors: Reid W. von Borstel, Michael K. Bamat
  • Acylated pyrimidine nucleosides for treatment of systemic inflammation and inflammatory hepatitis
    Patent number: 5691320
    Abstract: Pyrimidine nucleotide precursors including acyl derivatives of cytidine, uridine, and orotate, and uridine phosphorylase inhibitors, and their use in enhancing resistance to sepsis or systemic inflammation are disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: November 25, 1997
    Assignee: Pro-Neuron, Inc.
    Inventors: Reid W. von Borstel, Michael K. Bamat, Bradley M. Hiltbrand
  • Acylated uridine and cytidine for elevating tissue uridine and cytidine
    Patent number: 5583117
    Abstract: General methods for delivering exogenous cytidine or uridine to the tissue of an animal comprising the administration of acylated cytidine or acylated uridine, respectively, are disclosed. Methods of treating myocardial infarction and cardiac insufficiency comprising the administration of acylated cytidine or acylated uridine, are also disclosed.
    Type: Grant
    Filed: October 25, 1993
    Date of Patent: December 10, 1996
    Assignee: Pro-Neuron, Inc.
    Inventors: Reid von Borstel, Michael K. Bamat
  • Method of delivering exogenous uridine or cytidine using acylated uridine or cytidine
    Patent number: 5470838
    Abstract: Methods of delivering exogenous uridine or cytidine to the tissue of an animal comprising the administration of acyl derivatives of uridine or cytidine, respectively, are disclosed. Also disclosed are methods for treating cardiac insufficiency, myocardial infarction, cirrhosis of the liver, each comprising administration of acyl derivatives of uridine or cytidine.
    Type: Grant
    Filed: December 30, 1992
    Date of Patent: November 28, 1995
    Assignee: Pro-Neuron, Inc.
    Inventors: Reld W. von Borstel, Michael K. Bamat
  • Methods for promoting wound healing with deoxyribonucleosides
    Patent number: 5246708
    Abstract: Methods are provided for promoting wound healing in animals by administering compositions containing two or more of the following 2'-deoxyribonucleosides: 2'-deoxyadenosine, 2'-deoxyguanosine, 2'-deoxy-cytidine, or thymidine. 3'- and 5'-phosphate derivatives of these 2'-deoxynucleosides are also effective in promoting wound healing.
    Type: Grant
    Filed: July 13, 1992
    Date of Patent: September 21, 1993
    Assignee: Pro-Neuron, Inc.
    Inventors: Reid W. von Borstel, Michael K. Bamat