Abstract: Exemplary embodiments of the present disclosure relate to devices, systems, and methods for tissue resection in a body lumen of a patient, and may include a body extending along an axis and a distal cap positioned distally of the body and coupled to a shaft extending along the axis. The body and the distal cap may be movable relative to each other. An anchoring mechanism may be capable of engaging the body and the distal cap proximate a selected tissue for resection in the body lumen. A tissue capture device may be deployable from the tissue resection device such that a selected tissue for resection is securable by the tissue capture device. The tissue resection device may further include a tissue resecting device for resecting the selected tissue for resection.

Abstract: Exemplary embodiments of the present disclosure relate to devices, systems, and methods for tissue resection in a body lumen of a patient, and may include an elongate body having a cavity at a distal end and a tissue retractor extendable distally from the distal end of the elongate body. The tissue retractor may include an expansion mechanism. The expansion mechanism may include a plurality of arms each having a first end coupled around a distal cap and expandable radially outward from the distal cap such that an anchoring mechanism on a second end of the arms is engageable with selected tissue for resection of the body lumen. The tissue resection device may further include a tissue resecting device.

Abstract: Exemplary embodiments of the present disclosure relate to devices, systems, and methods for tissue resection in a body lumen of a patient, and may include a body extending along an axis and a distal cap positioned distally of the body and coupled to a shaft extending along the axis. The body and the distal cap may be movable relative to each other. An anchoring mechanism may be capable of engaging the body and the distal cap proximate a selected tissue for resection in the body lumen. A tissue capture device may be deployable from the tissue resection device such that a selected tissue for resection is securable by the tissue capture device. The tissue resection device may further include a tissue resecting device for resecting the selected tissue for resection.

Abstract: Exemplary embodiments of the present disclosure relate to devices, systems, and methods for tissue resection in a body lumen of a patient, and may include an elongate body having a cavity at a distal end and a tissue retractor extendable distally from the distal end of the elongate body. The tissue retractor may include an expansion mechanism. The expansion mechanism may include a plurality of arms each having a first end coupled around a distal cap and expandable radially outward from the distal cap such that an anchoring mechanism on a second end of the arms is engageable with selected tissue for resection of the body lumen. The tissue resection device may further include a tissue resecting device.

Abstract: A system for treating tissue includes a first anchoring device including a first anchoring element at a distal end thereof for anchoring the first anchoring device in a first target portion of tissue extending about a periphery of a tissue defect to be treated and a first suture receiving feature at a proximal end thereof. The system also includes a second anchoring device including a second anchoring element at a distal end thereof for anchoring the second anchoring device in a second target portion of tissue about the periphery of the tissue defect and a second suture receiving feature at a proximal end thereof. Furthermore, the system includes a suture configured to be passed through the first and second suture receiving features such that a tension applied to the suture draws the first and second anchoring devices toward one another to close the tissue defect.