Patents by Inventor Michael K. Hoffmann

Michael K. Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for modulating immune systems of animals
    Patent number: 5840318
    Abstract: Methods and compositions for modulating the immune system of animals by activating macrophages to release cytokines and down-regulating their sensitivity to bacterial endotoxin and to conversion to cytotoxic phenotypes by the administration of stress response factors released by stressed bacteria.Methods and compositions for protecting the viability of liquid or dried cultures of bacteria by the administration of stress response factors released by stressed bacteria.
    Type: Grant
    Filed: October 29, 1996
    Date of Patent: November 24, 1998
    Assignee: Immunom Technologies, Inc.
    Inventors: William E. Marshall, Michael K. Hoffmann
  • Process for making human antibody producing B-lymphocytes
    Patent number: 4444887
    Abstract: Antibody producing human B-lymphocytes are produced by a process which comprises culturing human B-lymphocytes in a tissue culture medium in the presence of an antigen; helper signal producing agents comprising monocytes or monocyte conditioned medium containing Interleukin 1 (I1-1), and helper T-lymphocytes or helper T-lymphocyte replacing factor; and human serum; and thereafter recovering the antibody producing cells from the medium.
    Type: Grant
    Filed: March 12, 1981
    Date of Patent: April 24, 1984
    Assignee: Sloan-Kettering Institute
    Inventor: Michael K. Hoffmann