Abstract: A surgical stapling assembly is disclosed. The assembly can include a cartridge body having cavities defined therein forming a pattern of openings in the deck of the cartridge body. The pattern can include longitudinally-repeating clusters of cavity ends. The assembly can also include fasteners removably positioned in the cavities. The pattern of openings can comprise openings on a first side of the cartridge body comprising inner openings each defining an inner proximal-to-distal axis oriented parallel to the longitudinal axis, outer openings each defining an outer proximal-to-distal axis obliquely-oriented relative to the longitudinal axis at an outer angle, and intermediate openings each defining an intermediate proximal-to-distal axis obliquely-oriented relative to the longitudinal axis at an intermediate angle, wherein the intermediate angle is different than the outer angle.

Abstract: A multi-function end effector includes a plurality of tool change mechanisms in a housing in which a spindle is also mounted for translation along an axis of the spindle. Each tool change mechanism has a gripper that releasably grips a tool holder in which a tool is mounted. The gripper of each tool change mechanism is movable between a stowed position to a tool-change position in which the gripper is coaxially aligned with the axis of the spindle for placing a tool holder held in the gripper in a position to be received by the spindle and for positioning the gripper to receive a tool holder from the spindle. The tools mounted in the tool holders include a drill bit, a countersink tool, and a fastener insertion tool. The end effector also includes a fastener feed system, a hammer device, and a sealant applicator.