Patents by Inventor Michael K. Mansour

Michael K. Mansour has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for generating universal and custom MHC/HLA-compatible hematopoietic progenitor cells
    Patent number: 11564942
    Abstract: Disclosed herein are methods for generating universal MHC/HLA-compatible hematopoietic progenitor cells and methods for generating custom patient-specific MHC/HLA-compatible hematopoietic progenitor cells. Compositions comprising the universal and custom hematopoietic progenitor cells and therapeutic applications thereof are also disclosed.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: January 31, 2023
    Assignees: The General Hospital Corporation, President and Fellows of Harvard College
    Inventors: Michael K. Mansour, David B. Sykes, David T. Scadden
  • BACTERICIDAL METHODS AND COMPOSITIONS
    Publication number: 20210060351
    Abstract: Methods of the present invention comprise photoinactivation of catalase in combination with low-concentration peroxide solutions and/or ROS generating agents to provide antibacterial effects.
    Type: Application
    Filed: August 28, 2020
    Publication date: March 4, 2021
    Applicants: THE GENERAL HOSPITAL CORPORATION, PULSETHERA CORPORATION
    Inventors: Pu-Ting DONG, Jie HUI, Ji-Xin CHENG, Yifan ZHU, Michael K. MANSOUR
  • METHODS FOR GENERATING UNIVERSAL AND CUSTOM MHC/HLA-COMPATIBLE HEMATOPOIETIC PROGENITOR CELLS
    Publication number: 20190201440
    Abstract: Disclosed herein are methods for generating universal MHC/HLA-compatible hematopoietic progenitor cells and methods for generating custom patient-specific MHC/HLA-compatible hematopoietic progenitor cells. Compositions comprising the universal and custom hematopoietic progenitor cells and therapeutic applications thereof are also disclosed.
    Type: Application
    Filed: February 17, 2017
    Publication date: July 4, 2019
    Applicants: THE GENERAL HOSPITAL CORPORATION, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Michael K. MANSOUR, David B. SYKES, David T. SCADDEN
  • Fungal-derived carbohydrate-conjugated scaffold
    Patent number: 9291616
    Abstract: The present invention provides for compositions and methods for a purified fungal carbohydrate-linked polymer bead platform, which can serve as an artificial fungus-like particle to measure specific patient immune responses to fungal carbohydrate antigens. A specific embodiment comprises a purified ?-1,3-glucan chemically conjugated to a polymer bead.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: March 22, 2016
    Assignee: THE GENERAL HOSPITAL CORPORATION
    Inventors: Jatin M. Vyas, Jenny M. Tam, Michael K. Mansour
  • FUNGAL-DERIVED CARBOHYDRATE-CONJUGATED SCAFFOLD
    Publication number: 20140127267
    Abstract: The present invention provides for compositions and methods for a purified fungal carbohydrate-linked polymer bead platform, which can serve as an artificial fungus-like particle to measure specific patient immune responses to fungal carbohydrate antigens. A specific embodiment comprises a purified ?-1,3-glucan chemically conjugated to a polymer bead.
    Type: Application
    Filed: April 9, 2012
    Publication date: May 8, 2014
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Jatin M. Vyas, Jenny M. Tam, Michael K. Mansour