Patents by Inventor Michael K. O'Hara

Michael K. O'Hara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7754222
    Abstract: The present invention provides safe vaccines and methods of preparing such vaccines. The vaccines of the present invention contain at least two live mutant viruses of the same family or nucleic acid molecules encoding such viruses, wherein each of the two viruses or the encoding nucleic acids contains a mutation that confers a desirable phenotype and the mutations in the viruses reside in the same genomic site such that the mutant viruses cannot recombine with each other to eliminate the mutations.
    Type: Grant
    Filed: April 4, 2008
    Date of Patent: July 13, 2010
    Assignee: Pharmacia & Upjohn Company, LLC
    Inventors: Siao-Kun Wan Welch, Jay Gregory Calvert, Michael K O'Hara, Xuemei Cao
  • Publication number: 20080286302
    Abstract: The present invention provides safe vaccines and methods of preparing such vaccines. The vaccines of the present invention contain at least two live mutant viruses of the same family or nucleic acid molecules encoding such viruses, wherein each of the two viruses or the encoding nucleic acids contains a mutation that confers a desirable phenotype and the mutations in the viruses reside in the same genomic site such that the mutant viruses cannot recombine with each other to eliminate the mutations.
    Type: Application
    Filed: April 4, 2008
    Publication date: November 20, 2008
    Applicants: PFIZER INC., PFIZER PRODUCTS INC.
    Inventors: Siao-Kun Wan Welsh, Jay Gregory Calvert, Michael K. O'Hara, Xuemei Cao
  • Patent number: 7361357
    Abstract: The present invention provides safe vaccines and methods of preparing such vaccines. The vaccines of the present invention contain at least two live mutant viruses of the same family or nucleic acid molecules encoding such viruses, wherein each of the two viruses or the encoding nucleic adds contains a mutation that confers a desirable phenotype and the mutations in the viruses reside in the same genomic site such that the mutant viruses cannot recombine with each other to eliminate the mutations.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: April 22, 2008
    Assignees: Pfizer Inc., Pfizer Products Inc.
    Inventors: Siao-Kun Wan Welch, Jay Gregory Calvert, Michael K. O'Hara, Xuemei Cao
  • Publication number: 20020058039
    Abstract: Methods to measure the duration of adequate immune memory for animal vaccines involving a retrospective analysis utilizing veterinary vaccine administration histories and clinical histories, and markers of immunity of animals in the field to derive a vaccine's duration of adequate immune memory.
    Type: Application
    Filed: April 19, 2001
    Publication date: May 16, 2002
    Inventors: Michael J. Coyne, Dennis J. Kowalski, David R. McGavin, Michael K. O'Hara