Abstract: The invention relates to a method of segmenting a three-dimensional structure, contained in an object, from one or more two-dimensional images which represent a slice of the object. The method utilizes a deformable model whose surface is formed by a network of meshes which connect network points on the surface of the model to one another. First there are determined the meshes which intersect at least one image and a point on the surface of the structure to be segmented is searched along a search line which traverses the mesh and extends in the image. Subsequently, the position of the network points of the model is calculated anew. These steps are repeated a number of times and the model ultimately obtained, that is, after several deformations, is considered to be the segmentation of the three-dimensional structure from the two-dimensional images.

Abstract: A method of segmenting a selected region from a multi-dimensional dataset, which method comprises the steps of setting up a shape model representing the general outline of the selected region and setting up an adaptive mesh. The adaptive mesh represents an approximate contour of the selected region. The adaptive mesh is initialized on the basis of the shape model. Furthermore, the adaptive mesh is deformed in dependence on the shape model and on feature information of the selected region.

Abstract: The present invention relates to conjugates comprising a compound capable of emitting fluorescence, a linker and a protein. The present invention also concerns the preparation of such conjugates as well as their use.

Abstract: A machine for processing hollow glass objects (8) is described. The machine includes a sequence of like processing units (1) to (15) and (A, B) on which a small number of processing steps can be carried out on the workpiece (8). The workpieces (8) are brought to the processing unit on a clock-driven loading belt (4) and taken therefrom. A workpiece, which is being processed in a unit, is held during the entire sequence by one and the same workpiece holder. Each processing unit includes two separate handling units with which two workpieces run through the workstations time displaced. The machine arrangement permits processing units to be taken out or switched into the line without a production standstill.

Abstract: This invention relates to a process for the preparation of polyether-including chlorins and/or bacteriochlorins, comprising the following steps:(a) bonding a polyether to a porphyrin and(b) reacting the polyether-including porphyrin with a reducing agent.Furthermore, this invention concerns the polyether-including chlorins and bacteriochlorins, obtained by the process, as well as the use thereof for the photodynamic treatment of tumors.