Patents by Inventor Michael Keeley

Michael Keeley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240417499
    Abstract: Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
    Type: Application
    Filed: August 30, 2024
    Publication date: December 19, 2024
    Inventors: Steve Plotkin, Gregory M. Cruise, Edward Michael Keeley, Renee Yu, Clayton Harris
  • Publication number: 20240383972
    Abstract: The present disclosure relates to methods of slowing cognitive decline in mild-to-moderate and moderate Alzheimer's disease, and other Tau pathologies, using anti-Tau antibodies. The disclosure provides first-in-class immunotherapy for use in reducing clinical decline in mild-to-moderate AD and moderate AD, in particular, significantly reducing rate of decline in cognitive capacity to a clinically meaningful extent, and significantly retaining memory. The disclosure also relates to use of anti-Tau antibodies to intercept cell-to-cell spread of pathological Tau in the brains of patients with AD or related Tauopathies.
    Type: Application
    Filed: February 26, 2024
    Publication date: November 21, 2024
    Inventors: Edmond Huatung Teng, Balazs Toth, Paul Manser, Michael Keeley
  • Patent number: 12077622
    Abstract: Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
    Type: Grant
    Filed: January 24, 2022
    Date of Patent: September 3, 2024
    Assignee: Terumo Corporation
    Inventors: Steve Plotkin, Gregory M. Cruise, Edward Michael Keeley, Renee Yu, Clayton Harris
  • Publication number: 20240108781
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Application
    Filed: October 6, 2023
    Publication date: April 4, 2024
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Patent number: 11801326
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Grant
    Filed: October 6, 2020
    Date of Patent: October 31, 2023
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Publication number: 20230334844
    Abstract: A computer implemented method of performing single pass optical character recognition (OCR) including at least one fully convolutional neural network (FCN) engine including at least one processor and at least one memory, the at least one memory including instructions that, when executed by the at least processor, cause the FCN engine to perform a plurality of steps. The steps include preprocessing an input image, extracting image features from the input image, determining at least one optical character recognition feature, building word boxes using the at least one optical character recognition feature, determining each character within each word box based on character predictions and transmitting for display each word box including its predicted corresponding characters.
    Type: Application
    Filed: June 23, 2023
    Publication date: October 19, 2023
    Inventors: David COLWELL, Michael KEELEY
  • Patent number: 11710302
    Abstract: A computer implemented method of performing single pass optical character recognition (OCR) including at least one fully convolutional neural network (FCN) engine including at least one processor and at least one memory, the at least one memory including instructions that, when executed by the at least processor, cause the FCN engine to perform a plurality of steps. The steps include preprocessing an input image, extracting image features from the input image, determining at least one optical character recognition feature, building word boxes using the at least one optical character recognition feature, determining each character within each word box based on character predictions and transmitting for display each word box including its predicted corresponding characters.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: July 25, 2023
    Assignee: TRICENTIS GMBH
    Inventors: David Colwell, Michael Keeley
  • Publication number: 20220144990
    Abstract: Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
    Type: Application
    Filed: January 24, 2022
    Publication date: May 12, 2022
    Inventors: Steve Plotkin, Gregory M. Cruise, Edward Michael Keeley, Renee Yu, Clayton Harris
  • Patent number: 11261274
    Abstract: Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: March 1, 2022
    Assignee: Terumo Corporation
    Inventors: Steve Plotkin, Gregory M. Cruise, Edward Michael Keeley, Renee Yu, Clayton Harris
  • Publication number: 20210142093
    Abstract: A computer implemented method of performing single pass optical character recognition (OCR) including at least one fully convolutional neural network (FCN) engine including at least one processor and at least one memory, the at least one memory including instructions that, when executed by the at least processor, cause the FCN engine to perform a plurality of steps. The steps include preprocessing an input image, extracting image features from the input image, determining at least one optical character recognition feature, building word boxes using the at least one optical character recognition feature, determining each character within each word box based on character predictions and transmitting for display each word box including its predicted corresponding characters.
    Type: Application
    Filed: November 6, 2020
    Publication date: May 13, 2021
    Inventors: David Colwell, Michael Keeley
  • Publication number: 20210023261
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Application
    Filed: October 6, 2020
    Publication date: January 28, 2021
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Patent number: 10828388
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: November 10, 2020
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Publication number: 20200131287
    Abstract: Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
    Type: Application
    Filed: November 22, 2019
    Publication date: April 30, 2020
    Inventors: Steve Plotkin, Gregory M. Cruise, Edward Michael Keeley, Renee Yu, Clayton Harris
  • Patent number: 10519264
    Abstract: Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: December 31, 2019
    Assignee: Terumo Corporation
    Inventors: Steve Plotkin, Gregory M. Cruise, Edward Michael Keeley, Renee Yu, Clayton Harris
  • Publication number: 20190192726
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Application
    Filed: February 27, 2019
    Publication date: June 27, 2019
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Patent number: 10258716
    Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: April 16, 2019
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Rob Greene, Clayton Harris
  • Patent number: 10194915
    Abstract: Described are devices for implantation comprising a hydrogel filament wherein the hydrogel filament includes a low molecular weight ethylenically unsaturated macromer, an ethylenically unsaturated monomer, and a visualization agent. Methods of making and using these devices are also described.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: February 5, 2019
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael J. Constant, Edward Michael Keeley, Terrance T. Tran
  • Publication number: 20190031798
    Abstract: Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
    Type: Application
    Filed: September 28, 2018
    Publication date: January 31, 2019
    Inventors: Steve Plotkin, Gregory M. Cruise, Edward Michael Keeley, Renee Yu, Clayton Harris
  • Patent number: 10124090
    Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: November 13, 2018
    Assignee: Terumo Corporation
    Inventors: Michael Constant, Edward Michael Keeley, Joshua Garretson, Gregory M. Cruise, Wendy Graczyk
  • Patent number: 10118980
    Abstract: Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: November 6, 2018
    Assignee: Terumo Corporation
    Inventors: Steve Plotkin, Gregory M. Cruise, Edward Michael Keeley, Renee Yu, Clayton Harris