Patents by Inventor Michael Keil

Michael Keil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method For Production Of 1-Alkyl-3-Phenyluracils
    Publication number: 20080293941
    Abstract: The present invention relates to a process for preparing 1-alkyl-3-phenyluracils of the formula I where the variables R1 to R7 are as defined in the description by reacting 3-phenyluracils of the formula II and alkylating agents of the formula III R1-L1 ??III, with one another, wherein during the entire reaction the pH is kept in a range from 1 to 6 by adding base a little at a time.
    Type: Application
    Filed: May 18, 2006
    Publication date: November 27, 2008
    Applicant: BASF AKTIENGESELLSCHAFT
    Inventors: Joachim Gebhardt, Sandra Lohr, Michael Keil, Thomas Schmidt, Jan Hendrik Wevers, Helmut Zech, Rudolf Haberler
  • Method For The Production Of 1,3,5-Trifluoro-2,4,6-Trichlorobenzene From Fluorobenzene Derivatives
    Publication number: 20080214878
    Abstract: Method for the production of 1,3,5-trifluoro-2,4,6-trichlorobenzene from fluorobenzene comprising steps A) and B): A) chlorination of fluorobenzene derivatives of formula (II), in which X=fluorine of H, Z=nitro, bromo or chloro and n=0 or 1-4 and B) fluorination of the distillation residue and separation by distillation of the 1,3,5-trifluoro-2,4,6-trichlorobenzene thus produced.
    Type: Application
    Filed: April 21, 2006
    Publication date: September 4, 2008
    Applicant: BASF Aktiengesellschaft
    Inventors: Michael Rack, Sebastian Peer Smidt, Manuel Budich, Volker Maywald, Michael Keil, Bernd Wolf
  • Method for Production of Substituted Phenylmalonate Esters, Novel Phenylmalonate Esters and Use Thereof
    Publication number: 20080200675
    Abstract: A process for preparing substituted phenylmalonic esters of the formula in which R is alkyl and Q is halogen, alkyl, alkoxy, haloalkyl or haloalkoxy and the index m is an integer from 1 to 5, where the groups Q can be identical or different if the index m is greater than 1, comprising steps A), B) and C): A) reaction of compounds of the formula II, in which the variables are as defined for formula I to give compounds of the formula III, B) conversion of the compounds of the formula III into ketals of the formula IV in which R? is C1-C4-alkyl or benzyl, C) hydrolysis of the compounds of the formula IV to give compounds of the formula I; novel phenylmalonic ester derivatives, and their use as intermediates.
    Type: Application
    Filed: June 23, 2006
    Publication date: August 21, 2008
    Applicant: BASF Aktiengesellschaft
    Inventors: Norbert Gotz, Volker Maywald, Michael Keil
  • Method for Producing 5-Halo-2,4,6-Trifluoroisophthalic Acid
    Publication number: 20080146839
    Abstract: The invention relates to a method for producing 5-halo-2,4,6-tifluoroisophthalic acid of formula (I), wherein X represents F, Cl, Br, or I, by hydrolysis of 5-halo-2,4,6-trifluoroisophthalodinitrile of formula (II). Said invention is characterised in that in a first step, isophthalodinitrile (II) or a solution containing isophthalodinitrile (II) is reacted with a concentrated sulphuric acid at room temperature in order to form a 5-halo-2,4,6-trifluoroisophthalodiamide of general formula (III), and is, subsequently, heated and in a second step, isophthalic acid (I) is produced after additional heating and addition of water.
    Type: Application
    Filed: March 16, 2006
    Publication date: June 19, 2008
    Applicant: BASF Aktiengesellschaft
    Inventors: Michael Rack, Sebastian Peer Smidt, Manuel Budich, Volker Maywald, Michael Keil, Bernd Wolf
  • PUNCTURING SYSTEM FOR WITHDRAWING A BODY FLUID
    Publication number: 20080082023
    Abstract: The present invention provides a puncturing system for withdrawing body fluid. The puncturing system comprises a disposable puncturing unit, which includes a needle element for piercing into skin and a puncturing depth reference element with a skin contact area. The system includes a puncturing instrument which has a puncturing drive, wherein the puncturing drive is coupled by a coupling mechanism to the puncturing unit for driving the needle element to a puncturing depth, the puncturing depth being determined by the distance in the piercing direction between the skin contact area and the position of the tip of the needle at a reversal point of the puncturing movement. The puncturing depth reference element is connected to the needle element such that the puncturing depth reference element moves with the needle element during at least part of the puncturing movement.
    Type: Application
    Filed: September 1, 2007
    Publication date: April 3, 2008
    Inventors: Frank Deck, Ortrud Quarder, Thomas Weiss, Christian Horauf, Michael Keil, Ahmet Konya, Herbert Harttig, Felix Baader, Hans List, Karl-Peter Ebert
  • Method for the Production of 3-Phenyl (Thio) Uracils and Dithiouracils
    Publication number: 20080033174
    Abstract: The present invention relates to a process for preparing 3-phenyl(thio)uracils and -dithiouracils of the formula I where the variables are each as defined in the description, and also intermediates for their preparation.
    Type: Application
    Filed: July 13, 2005
    Publication date: February 7, 2008
    Applicant: BASF Aktiengesellschaft
    Inventors: Sandra Lohr, Joachim Gebhardt, Guido Mayer, Michael Keil, Thomas Schmidt, Bernd Wolf
  • Method for producing alkyl nitrites and alkyl dinitrites
    Patent number: 7314948
    Abstract: In a continuous process for the preparation of alkyl nitrites and dinitrites, an alkanol or dialkanol is first mixed with an aqueous mineral acid, the reaction mixture obtained is then reacted with an inorganic nitrite and the product obtained can then be isolated immediately.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: January 1, 2008
    Assignee: BASF Aktiengesellschaft
    Inventors: Steffen Kudis, Rene Lochtman, Manfred Ehresmann, Michael Keil, Joachim Gebhardt, Michael Rack, Ralf Schimetzek
  • Preparation of isoxazolin-3-ylacylbenzene
    Patent number: 7309802
    Abstract: A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: December 18, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Götz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Baumann
  • Preparation of -4-thioalkybrobenzene derivatives
    Patent number: 7301034
    Abstract: A process for preparing 4-thioalkylbromobenzene derivatives of the formula I where: R1 is C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, C3-C8-cycloalkyl, halogen, R2 is C1-C6-alkyl, C1-C6-alkoxy, C3-C8-cycloalkyl, C2-C6-alkenyl, cyano or a heterocyclic radical, R3 is C1-C6-alkyl, which comprises reacting a compound of the formula II, in which R1 and R2 are as defined above, with a dialkyl disulfide of the formula III R3—S—S—R3III in the presence of a nitrite and a catalyst in a suitable solvent is described.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: November 27, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Rene Lochtman, Michael Keil, Joachim Gebhardt, Michael Rack, Wolfgang von Deyn
  • Method for the production of benzophenones
    Patent number: 7253323
    Abstract: A process for preparing benzophenones of the formula I, where X may be chlorine, hydroxyl, methoxy or C1-C6-alkylcarbonyloxy, and Y may be chlorine or bromine, by reacting an acid chloride of the formula II where X and Y are as defined above with 3,4,5-trimethoxytoluene, which comprises carrying out the reaction in the presence of a) an aromatic hydrocarbon as a diluent and b) from 0.01 to 0.2 mol % of an iron catalyst, based on the acid chloride, c) at a temperature between 60° C. and the boiling point of the particular diluent.
    Type: Grant
    Filed: December 1, 2003
    Date of Patent: August 7, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Volker Maywald, Nico Hoffmann, Michael Keil, Uwe Josef Vogelbacher, Jan Hendrik Wevers
  • Preparation of Isoxazolin-3-Ylacylbenzene
    Publication number: 20070161800
    Abstract: A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.
    Type: Application
    Filed: March 11, 2007
    Publication date: July 12, 2007
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Gotz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Boumann
  • Mehtod for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils
    Publication number: 20060293520
    Abstract: A process is described for preparing 3-phenyl(thio)uracils or 3-phenyldithiouracils of the formula I, by reacting a phenyl iso(thio)cyanate of the formula II with an enamine of the formula III and, if appropriate, in a further step, the resulting 3-phenyl(thio)uracil or 3-phenyldithiouracil of the formula I where R1=R1a, when R1=hydrogen, is reacted with an aminating agent of the formula IV to give 3-phenyl(thio)uracils or 3-phenyldithiouracils of the formula I where R1=amino where the variables R1, R1a, R2, R3, R4, X1, X2, X3, Ar, A and L1 are each as defined in claim 1.
    Type: Application
    Filed: December 1, 2004
    Publication date: December 28, 2006
    Applicant: BASF AKTIENGESELLSCHAFT
    Inventors: Gerhard Hamprecht, Michael Puhl, Bernd Wolf, Michael Keil, Robert Reinhard, Werner Steitz, Guido Mayer
  • Method for producing o-chloromethyl benzoic acid chlorides
    Patent number: 7034181
    Abstract: The invention relates to a method for producing o-chloromethyl benzoic acid chlorides of formula (I), in which R1 to R4 can be the same or different and represent hydrogen C1–C4 alkyl, halogen or trifluoromethyl, by reaction benzo condensed lactones of formula (II), in which R1 to R4 have the above-mentioned meaning, with thionyl chloride. The inventive method is characterized in that the reaction is carried out in the presence of catalytic quantities of a Lewis acid and in the presence of catalytic quantities of a phosphine derivative.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: April 25, 2006
    Assignee: BASF Aktiengesellschaft
    Inventors: Roland Götz, Norbert Götz, Michael Keil, Bernd Wolf, Adrian Steinmetz, Armin Stamm, Jochem Henkelmann
  • Method for producing 3-trifluoromethylphenyl-4-cyanobenzyl ketone
    Patent number: 6992206
    Abstract: A process is described for preparing 3-trifluoromethylphenyl 4-cyanobenzyl ketone by reacting a C1–C2-alkyl 3-trifluoromethylbenzoate with 4-tolunitrile in an aprotic polar solvent or an aprotic polar solvent mixture in the presence of at least an equimolar amount of a base which is selected from potassium alkoxides of primary C1–C4-alkanols.
    Type: Grant
    Filed: April 25, 2003
    Date of Patent: January 31, 2006
    Assignee: BASF Aktiengesellschaft
    Inventors: Stefan Engel, Michael Keil, Christian Ott, Michael Rack
  • Method for the production of benzophenonen
    Publication number: 20060009659
    Abstract: A process for preparing benzophenones of the formula I, where X may be chlorine, hydroxyl, methoxy or C1-C6-alkylcarbonyloxy, and Y may be chlorine or bromine, by reacting an acid chloride of the formula II where X and Y are as defined above with 3,4,5-trimethoxytoluene, which comprises carrying out the reaction in the presence of a) an aromatic hydrocarbon as a diluent and b) from 0.01 to 0.2 mol % of an iron catalyst, based on the acid chloride, c) at a temperature between 60° C. and the boiling point of the particular diluent.
    Type: Application
    Filed: December 1, 2003
    Publication date: January 12, 2006
    Applicant: BASF Aktiengesellschaft
    Inventors: Volker Maywald, Nico Hoffmann, Michael Keil, Uwe Vogelbacher, Jan Wevers
  • Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their Preparation
    Publication number: 20060004220
    Abstract: A process for preparing phenyl iso(thio)cyanates of the formula I in which a compound of the formula II or its HCl adduct is reacted with a phosgenating agent where W is oxygen or sulfur and Ar and A are as defined in claim 1 is described. Moreover, the invention relates to the use of the phenyl iso(thio)cyanates for preparing crop protection agents.
    Type: Application
    Filed: October 29, 2003
    Publication date: January 5, 2006
    Inventors: Gerhard Hamprecht, Michael Puhl, Bernd Wolf, Norbert Gotz, Michael Keil, Robert Reinhard, Ingo Sagasser, Werner Seitz
  • Method for producing 3-trifluromethylphenyl-4-cyanobenzyl ketone
    Publication number: 20050171373
    Abstract: A process is described for preparing 3-trifluoromethylphenyl 4-cyanobenzyl ketone by reacting a C1-C2-alkyl 3-trifluoromethylbenzoate with 4-tolunitrile in an aprotic polar solvent or an aprotic polar solvent mixture in the presence of at least an equimolar amount of a base which is selected from potassium alkoxides of primary C1-C4-alkanols.
    Type: Application
    Filed: April 25, 2003
    Publication date: August 4, 2005
    Inventors: Stefan Engel, Michael Keil, Christian Ott, Michael Rack
  • Method for producing 2-chloromethylphenyl acetic acid derivatives
    Publication number: 20050113597
    Abstract: A process for preparing 2-(chloromethyl)phenylacetic acid derivatives of the formula I, where X is C1-C4-alkoxy or methylamino, by ether cleavage of compounds of the formula II, where R is C1-C4-alkyl, C1-C4-alkoxy, C1-C2-haloalkyl, C1-C4-alkylcarbonyl, C1-C4-alkylcarbonyloxy, halogen, nitro or cyano and X is as defined above comprises carrying out the reaction in the presence of hydrogen chloride and an inert solvent, and adding a catalyst to the reaction mixture selected from the group consisting of iron, indium and halides, oxides and triflates thereof.
    Type: Application
    Filed: February 6, 2003
    Publication date: May 26, 2005
    Inventors: Guido Mayer, Oliver Cullmann, Bernd Wolf, Michael Keil
  • Method for producing alkyl nitrites and alkyl dinitrites
    Publication number: 20040199003
    Abstract: In a continuous process for the preparation of alkylnitrites and dinitrites, an alkanol or dialkanol is first mixed with an aqueous mineral acid, the reaction mixture obtained is then reacted with an inorganic nitrite and the product obtained can then be isolated immediately.
    Type: Application
    Filed: January 29, 2004
    Publication date: October 7, 2004
    Inventors: Steffen Kudis, Rene Lochtman, Manfred Ehresmann, Michael Keil, Joachim Gebhardt, Michael Rack, Ralf Schimetzek
  • Method for producing o-chloromethyl benzoic acid chlorides
    Patent number: 6727385
    Abstract: A process for preparing o-chloromethylbenzoyl chlorides of the formula I, in which R1 to R4 can be identical or different and are hydrogen, C1-C4-alkyl, halogen or trifluoromethyl, by reacting benzo-fused lactones of the formula II, in which R1 to R4 are as defined above, with thionyl chloride, which comprises carrying out the reaction in the presence of catalytic amounts of boric acid, boric anhydride, borate, boronic acid or boronic acid esters and catalytic amounts of a quaternary ammonium salt is described.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: April 27, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: Roland Götz, Norbert Götz, Michael Keil, Bernd Wolf, Adrian Steinmetz, Armin Stamm, Jochem Henkelmann