Abstract: Various examples of embodiments of the invention generally relate to automating a clinical workflow, the clinical workflow including an analysis of one or more medical datasets and generation of a medical report based on the analysis. For example, machine-learning algorithms may be used for the analysis. The medical report may be generated based on one or more report templates.

Abstract: One or more example embodiments of the present invention relates to a method for generating a data processing pipeline for a cloud computing system, wherein the data processing pipeline comprises at least one software module for execution in at least one execution environment, wherein the execution environment has allocated execution environment information data. The method includes receiving at least one software module selection of a user, receiving at least one input data selection of a user, receiving at least one user planning input, checking a compliance with at least one of data protection requirements or technical requirements of the data processing pipeline, which is to be generated.

Abstract: Please substitute the new Abstract submitted herewith for the original Abstract: A hinge system of a hood of a vehicle has a hinge which is arranged between the hood and a mating element of the vehicle. The hinge is designed both for opening the hood and for raising the hood when the latter is in the closed state, and includes a lifting-piston actuator for initiating a raising movement of the hood. The lifting-piston actuator has a piston element which can be connected to the hinge and/or the hood in a form-fitting manner in order to limit freedom of movement of the hood.

Abstract: The present invention relates to methods, and devices to analyze the phenotype and/or genotype of cells obtained from tissue samples. In particular, the present invention relates to the analysis of the response of the cells as obtained to the exposure of a drug compound or combinations thereof. The methods of the present invention offer the particular advantage of being time-effective, and suitable for automatization.

Abstract: A medical data management system is for managing medical data. In an embodiment, the system includes a medical data gateway, including a processor connectable to a plurality of input devices, the medical data gateway being connected to a local network. Further, the processor is configured to carry out: collecting medical data, associated to a non-pseudonymized patient identifier and a data source identifier, from an input device; pseudonymizing at least the non-pseudonymized patient identifier of the medical data; exporting the pseudonymized medical data to a remote storage, the remote storage being part of a remote network external to the local network; allowing access to the non-pseudonymized patient identifier to a local application, running in the local network, and/or refusing access to the non-pseudonymized patient identifier to a remote application, running outside of the local network. A corresponding medical data management method is for managing medical data.

Abstract: A computer-implemented methods is for training a machine learning algorithm to detect anomalies in processes. A computer-implemented method is for detecting anomalies in processes. Further, data processing systems and a system are for detecting anomalies in processes. A training dataset of a process is provided including a first number of training usage sequences. A second number of process trees is created based upon the usage sequences by way of a process mining algorithm. The creation of the process trees is subject to a certain randomness.

Abstract: A gateway and a method are provided for securely storing (and/or securely retrieving) medical data the method for storing comprising at least steps of: obtaining, in a secure environment, medical data which include patient property data as well as patient identifier data wherein the patient identifier data indicate at least one patient to which the patient property data correspond; generating, in the secure environment de identified medical data by replacing the patient identifier data in the medical data with non-patient-identifying coded identifiers; generating, in the secure environment, a re-identifying database indicating correspondences between the non-patient-identifying coded identifiers and the patient identifier data; generating n encrypted re-identifying database by applying, in the secure environment, at least one symmetric and/or asymmetric encryption method to the re-identifying database; storing the encrypted re-identifying database and the de-identified medical data on a cloud storage outsi

Abstract: Please substitute the new Abstract submitted herewith for the original Abstract: A hinge system of a hood of a vehicle has a hinge which is arranged between the hood and a mating element of the vehicle. The hinge is designed both for opening the hood and for raising the hood when the latter is in the closed state, and includes a lifting-piston actuator for initiating a raising movement of the hood. The lifting-piston actuator has a piston element which can be connected to the hinge and/or the hood in a form-fitting manner in order to limit freedom of movement of the hood.

Abstract: The present invention relates to a method of characterizing a composition comprising two or more active drug compounds, the method comprising the steps of: a) a composition selection screen (CSS), in which screen a candidate composition comprising two or more active drug compounds is tested against a 3D microtissue derived from one or more cell line, and b) a composition validation screen (CVS), in which screen the candidate composition of step b) is tested against a 3D microtissue derived from a primary patient sample.

Abstract: Various examples of embodiments of the invention generally relate to automating a clinical workflow, the clinical workflow including an analysis of one or more medical datasets and generation of a medical report based on the analysis. For example, machine-learning algorithms may be used for the analysis. The medical report may be generated based on one or more report templates.

Abstract: A method is for inserting a further data block into a first ledger, the first ledger including data blocks. In an embodiment, the method includes receiving a further medical dataset via an interface; determining the further data block via a calculation unit. The further data block includes the further medical dataset and a further link information. The further link information includes a hash of at least one of the data blocks of the first ledger. Finally, in an embodiment the method includes inserting the further data block into the first ledger via the calculation unit.

Abstract: A method for generating a combined contrast medium and blood vessel representation of contrast-enhanced image data of breast tissue to be examined includes capturing first and second contrast-medium-influenced x-ray projection measurement data of the breast tissue with respective differing first and second x-ray energies. First and second image data sets are reconstructed based respectively on the first and second measurement data. A dual-energy image data set is ascertained based on the first and the second image data sets. A blood vessel image is ascertained based on at least one image data set. A blood vessel image is represented together with the dual-energy image data set in a combined contrast medium and blood vessel representation. An image data generating system is also provided.

Abstract: A method image scans a female breast in the context of projective digital mammography or tomosynthesis with prefiltered x-ray radiation. From a single scanning two spatially superimposing images are created on the basis of pixel-by-pixel or pixel-group-by-pixel-group different x-ray energy spectra. An x-ray mammography system contains a radiator-detector system having an x-ray tube with a filter for generating a prefiltered x-ray radiation having a first radiation spectrum and a radiation detector containing a multiplicity of partial areas which generate individual image pixels. The radiator-detector system is configured to the effect that the partial areas receive pixel-by-pixel or pixel-group-by-pixel-group different radiation spectra, such that the two images from different x-ray spectra are received with a single scanning of the female breast.

Abstract: A hinge device of a front hood of a motor vehicle is adjustable from a normal position into a protective position in the event of a collision. A front-hood surface and a lifting device with an actuator contact surface and a front-hood contact surface are provided on a front-hood-fastening part. An actuator surface can be brought to bear against the actuator contact surface and the front-hood contact surface can be brought to bear against the front-hood surface during an adjustment from the normal position into the protective position. The distance, which is provided substantially in the actuating direction of the actuator on the lifting device, between the front-hood contact surface and the actuator contact surface is greater than the distance between the actuator surface and the front-hood hinge-lever contact surface. Furthermore, a correspondingly equipped motor vehicle and a method for opening out the hinge device are provided.

Abstract: An operating method assists a diagnosing practitioner with describing the location of a target structure in a tomosynthesis image data record of a compressed breast of a patient. The target structure is localized by a first spatial information item. The method includes: a) ascertaining a first shape information item describing at least one first, compressed breast shape in the tomosynthesis image data record, b) determining a second shape information item describing the breast in a non-compressed breast shape, from the first shape information item, c) mapping the position of the target structure from the compressed breast shape and to the non-compressed breast shape using at least the second shape information item for ascertaining a second spatial information item relating to the non-compressed breast shape, and d) transforming the second spatial information item into a pictogram information item facilitating an abstracted pictorial representation and/or describing the latter.

Abstract: A hinge device of a front hood of a motor vehicle is adjustable from a normal position into a protective position in the event of a collision. A front-hood surface and a lifting device with an actuator contact surface and a front-hood contact surface are provided on a front-hood-fastening part. An actuator surface can be brought to bear against the actuator contact surface and the front-hood contact surface can be brought to bear against the front-hood surface during an adjustment from the normal position into the protective position. The distance, which is provided substantially in the actuating direction of the actuator on the lifting device, between the front-hood contact surface and the actuator contact surface is greater than the distance between the actuator surface and the front-hood hinge-lever contact surface. Furthermore, a correspondingly equipped motor vehicle and a method for opening out the hinge device are provided.

Abstract: A method for generating a combined projection image from a medical inspection object, includes steps of capturing a set of initial projection images; reconstructing a first and a second three-dimensional volume from the set of initial projection images; generating a first re-projection image from the first three-dimensional volume and a second re-projection image from the second three-dimensional volume; weighting the first re-projection image and the second re-projection image; and combining the weighted first re-projection image and second re-projection image for generating the combined projection image.

Abstract: A method for generating a synthetic two-dimensional mammogram with enhanced contrast for structures of interest includes acquiring a three-dimensional digital breast tomosynthesis volume having a plurality of voxels. A three-dimensional relevance map that encodes for the voxels the relevance of the underlying structure for a diagnosis is generated. A synthetic two-dimensional mammogram is calculated based on the three-dimensional digital breast tomosynthesis volume and the three-dimensional relevance map.

Abstract: A method for generating a combined contrast medium and blood vessel representation of contrast-enhanced image data of breast tissue to be examined includes capturing first and second contrast-medium-influenced x-ray projection measurement data of the breast tissue with respective differing first and second x-ray energies. First and second image data sets are reconstructed based respectively on the first and second measurement data. A dual-energy image data set is ascertained based on the first and the second image data sets. A blood vessel image is ascertained based on at least one image data set. A blood vessel image is represented together with the dual-energy image data set in a combined contrast medium and blood vessel representation. An image data generating system is also provided.

Abstract: A periodic time-varying model of a guide wire, other device, or vessel is created from higher contrast CINE acquisition. A multivariate curve regression is used for periodic, phase dependent motion modeling. This model is then used to locate or track the guide wire, other device or vessel in lower contrast fluoroscopy images during intervention.